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Best Over The Counter Medicine For Knee Pain (2024 Updated)

If you’re looking for relief from knee pain, you may be considering over the counter medicine as a solution. However, before you make your purchase, there are a few factors you should consider.

Firstly, it’s important to understand the cause of your knee pain. Are you experiencing acute pain from an injury, or is it chronic due to an underlying condition such as arthritis? Different types of over the counter medicine are designed to target specific types of pain, so it’s important to choose one that’s aligned with your needs.

Secondly, you should consider any existing medications you’re taking. Certain over the counter medicines may interact with other medications, which could result in negative side effects. Be sure to speak with your doctor or pharmacist if you’re unsure about which medicine is best for you.

Finding the right over the counter medicine for knee pain can be a daunting task. Here are a few questions to ask yourself before making your purchase: What are the active ingredients in the medicine? Are there any potential side effects? How long does it typically take to feel relief? By asking these questions and doing your research, you’ll be one step closer to finding the right product for your knee pain.

10 Best Over The Counter Medicine For Knee Pain

# Product Image Product Name Product Notes Check Price
1
This product is ideal for supporting everyday health by reducing aches and discomfort, improving joint, bone, and tissue health.
2
The product is ideal for providing powerful topical relief for arthritis pain without the need for a prescription.
3
The product is ideal for providing quick and easy hot and cold therapy for knee injuries or pain.
4
The supplement is ideal for supporting joint health and reducing inflammation and discomfort in back, knees, and hands.
5
This supplement is ideal for relieving sciatic nerve pain in the lower lumbar, hip, thigh, leg, and foot.
6
Ideal for relieving arthritis knee pain through heat and vibration therapy with adjustable settings and AC adapter power.
7
The product is ideal for improving memory, focus, concentration, cognitive function, and includes vitamins and clinically tested nootropics.
8
This product is ideal for supporting joint mobility, comfort, strength, flexibility, and bone health.
9
This product is ideal for improving memory and supporting healthy brain function.
10
The product is ideal for reducing the appearance of wrinkles, treating acne, and relieving muscle and joint pain throughout the body.
This product is ideal for supporting everyday health by reducing aches and discomfort, improving joint, bone, and tissue health.
The product is ideal for providing powerful topical relief for arthritis pain without the need for a prescription.
The product is ideal for providing quick and easy hot and cold therapy for knee injuries or pain.
The supplement is ideal for supporting joint health and reducing inflammation and discomfort in back, knees, and hands.
This supplement is ideal for relieving sciatic nerve pain in the lower lumbar, hip, thigh, leg, and foot.
Ideal for relieving arthritis knee pain through heat and vibration therapy with adjustable settings and AC adapter power.
The product is ideal for improving memory, focus, concentration, cognitive function, and includes vitamins and clinically tested nootropics.
This product is ideal for supporting joint mobility, comfort, strength, flexibility, and bone health.
This product is ideal for improving memory and supporting healthy brain function.
The product is ideal for reducing the appearance of wrinkles, treating acne, and relieving muscle and joint pain throughout the body.

1. Turmeric Mobility: Full Body Support Capsules

Inflamma-X is a full-body soothing supplement that contains a unique blend of clinically tested ingredients, including turmeric, boswellia, bromelain, tart cherry, and protease enzymes. This supplement balances enzymes in the body, providing relief from everyday aches and discomfort.

When taken consistently over 6 or more weeks, Inflamma-X enhances comfort and ease of movement. Users may experience early benefits within the first 2-3 weeks, such as enhanced joint flexibility and relief from aches and discomfort.

For optimal results, take 2 capsules daily on an empty stomach. Although the serving size is calculated for the average adult, it's recommended to consult with a healthcare provider to determine the appropriate serving size for your body.

LifeSeasons, the manufacturer of Inflamma-X, was created to make it easier and more affordable to achieve good health. Their products combine nature and science to create effective blends of vitamins, minerals, herbs, and nutrients. Each ingredient undergoes a rigorous testing process to ensure their purity, potency, and effectiveness, providing you with the best possible health results.

Pros

  • Contains a unique blend of clinically tested ingredients
  • Balances enzymes in the body to provide relief from everyday aches and discomfort
  • Enhances comfort and ease of movement when taken consistently over 6 or more weeks
  • Early benefits may be experienced within the first 2-3 weeks, such as enhanced joint flexibility
  • LifeSeasons products combine nature and science to create effective blends of vitamins, minerals, herbs, and nutrients

Cons

  • – May not provide immediate relief from aches and discomfort

2. Powerful Arthritis Pain Relief Gel – Voltaren (2-Pack)

The Voltaren Arthritis Pain Gel is an effective solution for those who are looking for powerful topical pain relief. It comes with two 3.5 oz/1 g tubes that will help reduce stiffness, aches and pains that arise due to arthritis. The product is clinically proven to relieve arthritis pain and improve mobility, making it a prescription strength arthritis pain relief product.

This nonsteroidal anti-inflammatory gel is the number one doctor recommended topical pain relief brand that provides an alternative to pills. It combines the benefits of an arthritis cream and gel for arthritis pain management. The Diclofenac Sodium Topical Gel penetrates deep to attack arthritis pain directly at the source of inflammation, treating arthritis pain rather than just masking it. With Voltaren, you can experience long-lasting relief from arthritis pain and get back to your daily activities without any discomfort.

Pros

  • Number one doctor recommended topical pain relief brand
  • Clinically proven to relieve arthritis pain
  • Improves mobility and reduces stiffness, aches, and pains
  • Provides long-lasting relief from arthritis pain
  • Nonsteroidal anti-inflammatory gel that treats arthritis pain rather than just masking it

3. Hyperice X Knee: Instant Hot/cold Therapy Device

The Hyperice X is a versatile pain relief device that uses cold and heat therapy to tackle inflammation, tension, and aches. It provides long-lasting relief without the need to change temperature, making it a convenient and hassle-free option for anyone in need of pain relief. The device is lightweight, cordless, and travel-friendly, making it easy to use at home or on the go, without any prep or cords. The device is app-controlled, allowing users to set the temperature to their desired level and enjoy fully automated contrast therapy.

The Hyperice X has a patented temperature control system that allows it to change from cold to hot in just 60 seconds. It has an adaptive fit that moves with the user, providing full coverage and maximum relief. The device is also TSA-approved, making it easy to carry on flights and take with you wherever you go.

Whether you are suffering from a sports injury, chronic pain, or just need relief from everyday aches and pains, the Hyperice X is a great option that is easy to use and provides long-lasting relief. With its app-controlled system, lightweight design, and long battery life, it is a top choice for anyone looking for a convenient and effective pain relief solution.

Pros

  • Provides long-lasting relief without any change in temperature
  • Adaptive fit that moves with the user
  • App-controlled temperature for convenience
  • Patented temperature control system
  • Lightweight and cordless design
  • Travel-friendly and TSA-approved

4. Joint Defender Capsules: Antioxidant Support & Relief

The Joint Health and Function Expert formula is a premium supplement designed to provide a solid foundation for healthy joint function. It contains five essential nutrients including Glucosamine, Chondroitin, MSM, Turmeric, and Boswellia. By working together, they help to reduce joint discomfort and promote comfortable movement.

The inflammation-balancing properties of Turmeric, Boswellia, Glucosamine, and Chondroitin work to reduce joint discomfort, while also maintaining cartilage health, supporting joint flexibility, and reducing daily joint stiffness. This supplement is ideal for those with an active lifestyle, as it can increase joint mobility, allowing them to enjoy activities they love.

This supplement is made in the USA and manufactured in a GMP-certified facility with globally-sourced ingredients. It is non-GMO, gluten-free, dairy-free, sugar-free, and soy-free. Additionally, it does not contain any shellfish, pork, or shark cartilage. The convenient flip-top bottle allows for easy on-the-go nutrition.

Pros

  • Contains five essential nutrients that work together to support healthy joint function
  • Reduces joint discomfort and promotes comfortable movement
  • Maintains cartilage health and supports joint flexibility
  • Ideal for those with an active lifestyle
  • Made in the USA in a GMP-certified facility with globally-sourced ingredients
  • Non-GMO, gluten-free, dairy-free, sugar-free, and soy-free
  • Does not contain any shellfish, pork, or shark cartilage
  • Convenient flip-top bottle for on-the-go nutrition

5. Sciatica Relief With Ala Vitamins – 10x Strength

Sciaticare is a doctor and neurologist recommended supplement that provides soothing comfort from the occasional jolting nerve pain or muscle weakness from your lower back to your buttocks and down to your leg, feet and toes. This supplement contains a powerful combination of non-chemical nutrients that support your lower lumbar nerves and soothe the discomfort of cramps and sharp nerve pain. The unique proprietary blend of powerful synergistic critical ingredients including R-ALA (10X more powerful than synthetic ALA), Acetyl L-Carnitine HCL, and Benfotiamine makes it one of the most comprehensive and potent nerve support formulas available today. Simply take 2 capsules 2x a day with meals. Capsule contents can be sprinkled on food if you prefer. Sciaticare is absolutely unique and is 10x stronger and more effective than the common, cheaper and synthetic form of Alpha Lipoic Acid (ALA) used in almost all other sciatic nerve supplement brands. There are no side effects as the formula is the best sciatic intensive soothing products with no added milk, eggs, wheat, tree nuts, peanuts, fish, shellfish, or ingredients from these sources. Be assured of no reactions if you are sensitive to these foods. Sciaticare capsules work to effectively soothe the occasional burning, shooting, numbing pain felt in the lower back, buttocks, legs, and calves. If you're not satisfied with this product, Sciaticare offers a 100% money-back guarantee.

Pros

  • Doctor and neurologist recommended supplement for sciatic nerve occasional pain
  • Provides soothing comfort from the occasional jolting nerve pain or muscle weakness
  • Powerful combination of non-chemical nutrients that support your lower lumbar nerves and soothe the discomfort of cramps and sharp nerve pain
  • Unique proprietary blend of powerful synergistic critical ingredients including R-ALA (10X more powerful than synthetic ALA), Acetyl L-Carnitine HCL, and Benfotiamine makes it one of the most comprehensive and potent nerve support formulas available today
  • No added milk, eggs, wheat, tree nuts, peanuts, fish, shellfish, or ingredients from these sources
  • Effective in soothing the occasional burning, shooting, numbing pain felt in the lower back, buttocks, legs, and calves
  • 100% money-back guarantee

6. Warm And Soothe: Heated Vibration Knee Brace

The PKSTONE knee brace wrap is designed to provide relief from arthritis knee pain and aid in injury recovery. It comes equipped with three heating and vibrating levels that can be controlled individually, or together for maximum effect. The heating function promotes circulation, relieves muscle soreness and cramps, and reduces joint pain, stiffness, and swelling. The knee massager is fast heating, providing almost instant relief to your knees.

The PKSTONE knee massager is a great gift for anyone suffering from chronic knee pain, meniscal tear, or muscular aches. It comes with an AC charger that can be plugged into a wall socket for use. The knee massager is perfect for use while watching TV or reading a book at home. The comfortable high-quality neoprene material ensures durability and warmth, making it an ideal choice for daily use.

Pros

  • Three heating and vibrating levels for customizable relief
  • Promotes circulation and reduces joint pain, stiffness, and swelling
  • Fast heating for instant relief
  • Can be used while watching TV or reading a book
  • High-quality neoprene material ensures durability and warmth

Cons

  • – May not fit all knee sizes

7. Neuriva Focus Capsules – Boost Brain Power Fast!

If you are looking to support your brain health, then the Nootropic Brain Support Capsules are a great option. These capsules contain Neurofactor, which is a whole fruit extract that has been clinically tested and shown to increase levels of the vital neuroprotein BDNF brain-derived neurotrophic factor. BDNF is known to support the connections between brain cells. The plant-sourced PS phosphatidylserine helps fuel memory and learning, while B Vitamins help support cognitive function.

The clinically tested Neurofactor helps support focus, concentration, and accuracy, making it perfect for those who need to stay sharp during the day. These capsules are also formulated with trustworthy ingredients, as they are vegetarian, gluten-free, GMO-free and decaffeinated. Additionally, they are guaranteed for freshness, purity, and labeled potency.

To get the most out of these capsules, adults 18 years and older should take one capsule daily at bedtime. For even better results, download the NEURIVA BRAIN GYM app from the App Store or Google Play to start assessing your skills and building your brain fitness routine. Please note that these statements have not been evaluated by the Food and Drug Administration, and this product is not intended to diagnose, treat, cure or prevent any disease.

Pros

  • Contains clinically tested Neurofactor which increases levels of the vital neuroprotein BDNF brain-derived neurotrophic factor
  • Plant-sourced PS phosphatidylserine helps fuel memory and learning
  • B Vitamins help support cognitive function
  • Vegetarian, gluten-free, GMO-free and decaffeinated
  • Guaranteed for freshness, purity, and labeled potency

Cons

  • – Results may vary from person to person

8. Joint Support Tablets For Mobility And Comfort.

Move Free Advanced with MSM is a dietary supplement that combines heritage joint support ingredients with the clinically studied mineral complex Uniflex. This product helps support the five signs of joint health, which are joint mobility, comfort, strength, flexibility, and lubrication. It also provides extra cartilage support to the joints.

The supplement contains Glucosamine, Chondroitin, Calcium Fructoborate, and MSM, which are essential building blocks of the joints. Glucosamine helps in the formation of cartilage that supports joint lubrication & smooth movement, while also supporting joint comfort, mobility, and flexibility. Chondroitin is a building block of cartilage that supports joint strength by resisting compression in the joints. MSM is a source of sulfur found in the body that is vital in the formation of collagen in joints, which supports the structure of cartilage.

Move Free Advanced with MSM has exclusive state-of-the-art technology that allows the same amount of powerful ingredients to be packed into a smaller tablet, making it easier to swallow. The recommended dosage is three tablets once a day with a meal or one tablet three times daily with meals. Each box of Move Free Advanced Glucosamine & Chondroitin, MSM provides 120 servings.

Move Free is a brand that started in the fitness community, helping athletes who experienced joint discomfort. Their goal is to keep people moving and to help support their joint health.

The flavor type of this product is unflavored, making it easy to take with meals or water.

Pros

  • Contains clinically studied mineral complex Uniflex that helps support joint comfort in as little as 14 days
  • Helps support the five signs of joint health – mobility, comfort, strength, flexibility, and lubrication
  • Provides extra cartilage support to the joints
  • Contains Glucosamine, Chondroitin, Calcium Fructoborate, and MSM, which are essential building blocks of the joints
  • Exclusive state-of-the-art technology allows the same amount of powerful ingredients to be packed into a smaller tablet, making it easier to swallow
  • Each box provides 120 servings, making it a good value for money

Cons

  • – May not be suitable for individuals with shellfish allergies as it contains Glucosamine derived from shellfish
  • – May cause mild stomach discomfort for some people

9. Memory Boost Pro: Brain Health & Function Support

Prevagen is a dietary supplement that has undergone extensive safety testing and demonstrated the ability to improve cognitive function in subgroups of participants who were cognitively normal or mildly impaired. The active ingredient in Prevagen is Apoaequorin, which is unique and has been proven safe by third-party experts. The supplement comes in an easy-to-swallow capsule and is recommended to be taken once a day in the morning, with or without food, for best results. A 7-day pill minder is also included to help you stay organized.

In a double-blinded, placebo-controlled trial, Prevagen was shown to improve cognitive function in adults over 40 years old who took one capsule daily for 90 days. The group taking Prevagen showed improvement according to computer-based testing. Additionally, Prevagen was the #1 recommended Memory Support brand in a 2022-2023 survey of pharmacists who recommend memory support products.

Made in the USA, Prevagen Extra Strength is BPA free and features letters and braille for each day of the week.

Pros

  • Improves cognitive function in subgroups of participants who were cognitively normal or mildly impaired
  • The active ingredient, Apoaequorin, has undergone extensive safety testing and is proven safe by third-party experts
  • Comes in an easy-to-swallow capsule and is recommended to be taken once a day in the morning, with or without food, for best results
  • Includes a 7-day pill minder to help you stay organized
  • Made in the USA and BPA free, with letters and braille for each day of the week

10. Cellumalite: 3-In-1 Led Therapy For Radiant Skin & Body

The Celluma LITE is an exceptional device that is FDA cleared and made in the USA. It is a perfect size for targeting specific areas of the body such as the face for anti-aging and acne, shoulders, and joints such as elbows, wrists, and knees for pain relief. The device can be used almost anywhere on the body for various treatments.

The Aches & Pain Mode of the device helps to reduce muscle pain and aid in strength conditioning, making it the perfect device to use before and after a workout.

The Celluma LITE measures 16” x 8” overall with a treatment area of 14” x 6”, making it an ideal size for at-home use. With a 2-year Manufacturer’s Limited Warranty, you can enjoy the benefits of this device for thousands of uses.

The Celluma LITE is the same technology you would find in a doctor's office or MedSpa, but in an over-the-counter size for your convenience. It is easy-to-use, portable, and lightweight, making it a perfect at-home solution for all your treatment needs.

Pros

  • FDA cleared
  • Made in the USA
  • Perfect size for targeted areas
  • Aches & Pain Mode for muscle pain relief
  • 2-year Manufacturer’s Limited Warranty
  • Same technology as found in a doctor's office or MedSpa
  • Portable and lightweight

Best Over The Counter Medicine For Knee Pain FAQs

Are there any side effects of taking over-the-counter medicines for knee pain?

Yes, there can be side effects of taking over-the-counter medicines for knee pain. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, are commonly used to relieve knee pain. However, prolonged use of these medicines can cause side effects such as stomach ulcers, kidney damage, and increased risk of heart attack or stroke. Acetaminophen, another commonly used medication for pain relief, can cause liver damage if taken in large doses or combined with alcohol. Topical creams and gels can also cause skin irritation or allergic reactions.

It is important to read the labels and follow the recommended dosages of over-the-counter medicines. If the pain persists or becomes severe, it is best to consult a doctor. They can help identify the underlying cause of the knee pain and prescribe appropriate medication or refer to a specialist if necessary. In addition to medication, lifestyle changes such as weight management, exercise, and physical therapy can also help manage knee pain.

Can over-the-counter medicines provide long-term relief for knee pain?

Over-the-counter medicines are typically used for short-term relief of knee pain. They can provide temporary relief by reducing inflammation and pain, but they are not recommended for long-term use. Long-term use of over-the-counter pain relievers may cause side effects, such as stomach ulcers, liver damage, and kidney problems.

If you are experiencing long-term knee pain, it is important to consult with a medical professional to determine the underlying cause of the pain. Depending on the cause, there may be additional treatments available, such as physical therapy, injections, or surgery.

In addition to seeking medical advice, there are other measures you can take to manage knee pain in the long-term. Maintaining a healthy weight, stretching regularly, and using proper form during physical activity can all help to reduce knee pain over time.

How do I choose the right over-the-counter medicine for my knee pain?

Choosing the right over-the-counter medicine for knee pain can be a daunting task, especially with so many options available. The first thing to consider is the type of pain you are experiencing. Is it a dull ache or sharp pain? Is it caused by inflammation or injury? Once you have identified the type of pain, you can choose a medicine that targets that specific issue.

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen are effective at reducing inflammation and relieving pain caused by conditions like arthritis. Acetaminophen is another option that can relieve pain without reducing inflammation.

It is important to read the labels carefully and follow the recommended dosage to avoid any potential side effects. If you have any preexisting medical conditions or are taking other medications, it is best to consult with a healthcare professional before taking any over-the-counter medicine.

In addition to medication, it is important to rest your knee and apply ice to reduce swelling. Gentle stretching and physical therapy exercises can also help alleviate pain and improve mobility.

What are the best over-the-counter medicines for knee pain relief?

Knee pain is a common ailment that can be caused by a variety of factors, including injury, arthritis, and overuse. When it comes to finding relief from knee pain, there are a number of over-the-counter medications that can help.

One of the most commonly used over-the-counter drugs for knee pain relief is nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen. These medications work by reducing inflammation and relieving pain. Another option is acetaminophen, which is a pain reliever that can help alleviate knee pain, although it doesn't reduce inflammation.

Topical pain relievers like creams and gels can also be effective for knee pain relief. These products contain ingredients like menthol or capsaicin that can provide a cooling or warming sensation to the affected area, helping to dull the pain.

It's important to note that while over-the-counter medications can be effective for knee pain relief, they may not be suitable for everyone. Always read the label and follow the recommended dosage instructions. If you have any underlying medical conditions or are taking other medications, it's best to consult with a healthcare professional before taking any new medications.

What is the recommended dosage for over-the-counter medicines for knee pain?

The recommended dosage for over-the-counter medications for knee pain may vary depending on the type of medication and the severity of the pain. Generally, it is recommended to follow the instructions on the label or as instructed by a healthcare professional. Common over-the-counter medications for knee pain include acetaminophen, ibuprofen, and naproxen. For acetaminophen, the recommended dosage is usually 500 to 1000 milligrams every 4 to 6 hours as needed, but it is important not to exceed 4000 milligrams in 24 hours. For ibuprofen and naproxen, the recommended dosage is usually 200 to 400 milligrams every 4 to 6 hours as needed, but it is important not to exceed 1200 milligrams in 24 hours for ibuprofen and 660 milligrams in 24 hours for naproxen. It is important to note that over-the-counter medications should not be used for prolonged periods of time without consulting a healthcare professional.

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