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20 Best Medicine For Tooth And Gum Pain (2022 Updated)

There are a variety of medicines that can be used for tooth and gum pain. Over-the-counter options include ibuprofen, acetaminophen, and aspirin. There are also numbing gels or creams that can be applied directly to the gums.

If the pain is severe, a doctor may prescribe a stronger pain reliever or antibiotic.

20 Best Medicine For Tooth And Gum Pain

Product Image Product Name Features Price

Dentek Instant Pain Relief, Advanced Kit

  • Comes with angled applicators for easy and precise application
  • The oral anesthetic provides temporary relief from toothaches and sore gums

Orajel Instant Pain Relief, Severe Toothache & Gum Relief Plus, Fast-Acting Liquid – 0.45 fl oz

  • Product Description
  • #1 Oral Pain Reliever for Toothache* New Look! Instant Pain Relief* Maximum Strength
  • Product Benefits

Orajel 4X Severe Toothache Oral Pain Reliever Cream – 0.33 oz

  • Developed to temporarily soothe oral pain, irritation, and injuries
  • The essence of gelatin helps in the natural healing of your teeth

Orajel Toothache & Gum, Instant Pain Relief, Nighttime, Formula with Chamomile, Cream – 0.25 oz

  • 3X More Active Ingredients.
  • New Formula!
  • Safety-Sealed Tube Tip.

Red Cross Complete Medication Kit, Toothache – 0.125 fl oz

  • Product Description
  • Fast Toothache Pain ReliefToothache MedicationCotton pelletsMetal Tweezers
  • Product Benefits

Orajel Maximum Double Relief Toothache Gel – 0.42 oz tube

  • Do not use if tube tip is cut prior to opening.
  • This preparation is intended for use in cases of toothache, only as a temporary expedient until a physician can be consulted.

Orajel Pain Reliever Gel, Toothache, Immediate, Regular Strength – 0.25 oz

  • Provides instant, effective relief from toothache pain
  • The gel form allows users to have more control of product placement during application

Orajel Instant Pain Relief for Severe Toothache, Cooling Gel, 0.25 oz by MyOTCStore

  • This high absorbing formula helps provide a quick relief
  • Formulated to provide temporary relief from toothache
  • The gel form is easy to apply

Anbesol Pain Relief, Instant, Maximum Strength, Liquid – 0.41 fl oz

  • Instant pain relief for toothaches, gum pain, canker sores & denture pain
  • Anbesol Maximum Strength is available in liquid forms

Hylands 4Kids Oral Pain Relief, 65 mg, Quick-Dissolving Tablets – 125 tablets

  • Product Description.
  • Natural ReliefHomeopathicToothache, Sensitive Teeth, Sweloling Gums, Oral Discomfort.
  • Product Benefits.

Orajel Dental Gel 5.3g Rapid Toothache Relief

  • Orajel Dental Gel can be used to rapidly relieve the pain caused
  • Broken tooth or a tooth that may require a filling
  • For direct application to the source of toothache

Orajel Dental Gel 5.3g Rapid Toothache Relief

  • Orajel Dental Gel can be used to rapidly relieve the pain caused
  • Broken tooth or a tooth that may require a filling
  • For direct application to the source of toothache
Dentek Instant Pain Relief, Advanced Kit
  • Comes with angled applicators for easy and precise application
  • The oral anesthetic provides temporary relief from toothaches and sore gums
Orajel Instant Pain Relief, Severe Toothache & Gum Relief Plus, Fast-Acting Liquid – 0.45 fl oz
  • Product Description
  • #1 Oral Pain Reliever for Toothache* New Look! Instant Pain Relief* Maximum Strength
  • Product Benefits
Orajel 4X Severe Toothache Oral Pain Reliever Cream – 0.33 oz
  • Developed to temporarily soothe oral pain, irritation, and injuries
  • The essence of gelatin helps in the natural healing of your teeth
Orajel Toothache & Gum, Instant Pain Relief, Nighttime, Formula with Chamomile, Cream – 0.25 oz
  • 3X More Active Ingredients.
  • New Formula!
  • Safety-Sealed Tube Tip.
Red Cross Complete Medication Kit, Toothache – 0.125 fl oz
  • Product Description
  • Fast Toothache Pain ReliefToothache MedicationCotton pelletsMetal Tweezers
  • Product Benefits
Orajel Maximum Double Relief Toothache Gel – 0.42 oz tube
  • Do not use if tube tip is cut prior to opening.
  • This preparation is intended for use in cases of toothache, only as a temporary expedient until a physician can be consulted.
Orajel Pain Reliever Gel, Toothache, Immediate, Regular Strength – 0.25 oz
  • Provides instant, effective relief from toothache pain
  • The gel form allows users to have more control of product placement during application
Orajel Instant Pain Relief for Severe Toothache, Cooling Gel, 0.25 oz by MyOTCStore
  • This high absorbing formula helps provide a quick relief
  • Formulated to provide temporary relief from toothache
  • The gel form is easy to apply
Anbesol Pain Relief, Instant, Maximum Strength, Liquid – 0.41 fl oz
  • Instant pain relief for toothaches, gum pain, canker sores & denture pain
  • Anbesol Maximum Strength is available in liquid forms
Hylands 4Kids Oral Pain Relief, 65 mg, Quick-Dissolving Tablets – 125 tablets
  • Product Description.
  • Natural ReliefHomeopathicToothache, Sensitive Teeth, Sweloling Gums, Oral Discomfort.
  • Product Benefits.
Orajel Dental Gel 5.3g Rapid Toothache Relief
  • Orajel Dental Gel can be used to rapidly relieve the pain caused
  • Broken tooth or a tooth that may require a filling
  • For direct application to the source of toothache
Orajel Dental Gel 5.3g Rapid Toothache Relief
  • Orajel Dental Gel can be used to rapidly relieve the pain caused
  • Broken tooth or a tooth that may require a filling
  • For direct application to the source of toothache

1. Dentek Instant Pain Relief, Advanced Kit

Dentek Instant Pain Relief, Advanced Kit

  • Comes with angled applicators for easy and precise application
  • The oral anesthetic provides temporary relief from toothaches and sore gums
  • Its mint flavor offers a fresh feel upon application

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Product Details

Specifications

Details
Area of Application Gums
Number of Applicators 50
Recommended Age Group Adult
Disposable Yes
Gender Unisex

Reviews From Real Customers

sofia.b

2. Orajel Instant Pain Relief, Severe Toothache & Gum Relief Plus, Fast-Acting Liquid – 0.45 fl oz

Orajel Instant Pain Relief, Severe Toothache & Gum Relief Plus, Fast-Acting Liquid - 0.45 fl oz

  • Product Description
  • #1 Oral Pain Reliever for Toothache* New Look! Instant Pain Relief* Maximum Strength
  • Product Benefits
  • Ingredients
  • Special Note

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CVS Pharmacy

Product Details

Specifications

Details
Units in Package 1
Unit Size 0.45 fl oz
Indications Uses: For the temporary relief of pain due to canker sores; minor injury of the mouth and gums; minor irritation of the mouth and gums caused by dentures.
Directions Directions: Remove imprinted safety seal from bottle cap. Adults and Children 2 Years of Age and Over: Apply product with cotton swab or finger to the affected area. Use up to 4 times daily or as directed by a physician or healthcare provider. Children Under 12 Years of Age: Should be supervised in the use of this product. Children Under 2 Years of Age: Ask a physician or healthcare provider.
Ingredients Active Ingredients: Benzocaine (20%), Menthol (0.1%). Purpose: Oral Pain Reliever, Oral Pain Reliever. Inactive Ingredients: Alcohol (54.5% by Volume), Flavor, Polyethylene Glycol, Red 40, Sodium Saccharin, Water, Yellow 5.

Reviews From Real Customers

Alexandra ND
ameaney

3. Orajel 4X Severe Toothache Oral Pain Reliever Cream – 0.33 oz

Orajel 4X Severe Toothache Oral Pain Reliever Cream - 0.33 oz

  • Developed to temporarily soothe oral pain, irritation, and injuries
  • The essence of gelatin helps in the natural healing of your teeth
  • Get relief from toothaches and gum pain with the mineral oil extracts

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Target

Product Details

Specifications

Details
Units in Package 1
Unit Size 0.33 oz
Indications Uses: For the temporary relief of pain due to minor irritation or injury of the mouth and gums. First aid to help prevent infection in minor oral irritation.
Directions Adults and Children 2 Years of Age and Over: Apply to affected area up to 4 times daily or as directed by a dentist or doctor up to 4 times daily or as directed by a dentist or doctor. Children Under 12 Years of Age: Ask a doctor before use. Should be supervised in the use of this product. Children Under 2 Years of Age: Do not use.
Ingredients Active Ingredients: Benzalkonium Chloride (0.1%), Benzocaine (20%), Menthol (0.26%), Zinc Chloride (0.15%). Purposes: Oral Antiseptic, Oral Pain Reliever, Oral Pain Reliever, Oral Astringent. Inactive Ingredients: Ammonium Glycyrrhizate, Flavor, PEG-8, PEG-75, PEG/PPG 116/66 Copolymer, Poloxamer 407, Sodium Saccharin, Sorbic Acid, Titanium Dioxide, Water.

Reviews From Real Customers

jessica.h
Oceanbreezes
TheFishingAnt

4. Orajel Toothache & Gum, Instant Pain Relief, Nighttime, Formula with Chamomile, Cream – 0.25 oz

Orajel Toothache & Gum, Instant Pain Relief, Nighttime, Formula with Chamomile, Cream - 0.25 oz

  • 3X More Active Ingredients.
  • New Formula!
  • Safety-Sealed Tube Tip.
  • Instant Pain Relief.
  • Long-Lasting Cream.

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Walmart
Walgreens.com

Product Details

Specifications

Details
Units in Package 1
Unit Size 0.25 oz
Indications Uses: For the temporary relief of pain due to minor irritation or injury of the mouth and gums. First aid to help prevent infection in minor oral irritation.
Directions Adults and Children 2 Years of Age and Over: Apply to affected area up to 4 times daily or as directed by a dentist or doctor. Children Between 2 and 12 Years of Age: Ask a doctor before use. Should be supervised in the use of this product. Children Under 2 Years of Age: Do not use.
Ingredients Active Ingredients: Benzalkonium Chloride (0.13%), Benzocaine (20%), Menthol (0.26%), Zinc Chloride (0.15%). Purposes: Oral Pain Reliever, Oral Pain Reliever, Oral Pain Reliever, Oral Astringent. Inactive Ingredients: Ammonium Glycyrrhizate, Chamomile, Flavor, PEG-8, PEG-75, PEG/PPG 116/66 Copolymer, Poloxamer 407, Sodium Saccharin, Sorbic Acid, Titanium Dioxide, Water.

5. Red Cross Complete Medication Kit, Toothache – 0.125 fl oz

Red Cross Complete Medication Kit, Toothache - 0.125 fl oz

  • Product Description
  • Fast Toothache Pain ReliefToothache MedicationCotton pelletsMetal Tweezers
  • Product Benefits
  • Ingredients
  • Special Note

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Amazon
Walmart
Walgreens.com
Rite Aid

Product Details

Specifications

Details
Units in Package 1
Unit Size 0.125 fl oz
Indications Temporarily relieves throbbing, persistent toothache due to a cavity until a dentist can be seen.
Directions Rinse tooth with water to remove any food particles from the cavity. Using tweezers immerse cotton pellet in medication. To prevent dripping, squeeze gently between fingers to remove excess liquid. Place pellet in tooth cavity for one minute without touching surrounding tissues, then remove. Supervise children using this product. Adults and Children 12 Years and Over: Use to 4 times daily or as directed by a dentist or doctor. Children Under 12 Years: Ask a dentist or doctor.
Ingredients Active Ingredient: Eugenol (85%). Inactive Ingredient: Sesame Oil.

Reviews From Real Customers

HSmith
Maximoose
JJJJJJHHHHH

6. MediNatura Periodontal & Tooth Pain Relief 100 Tabs

MediNatura Periodontal & Tooth Pain Relief 100 Tabs

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Walmart – Swanson Health Products
Swanson Health Products

Product Details

Specifications

Details
Effectiveness 4.4 / 5

Reviews From Real Customers

Dean
BarbaraT
WaltraudH

7. Orajel Maximum Double Relief Toothache Gel – 0.42 oz tube

Orajel Maximum Double Relief Toothache Gel - 0.42 oz tube

  • Do not use if tube tip is cut prior to opening.
  • This preparation is intended for use in cases of toothache, only as a temporary expedient until a physician can be consulted.
  • Do not use continuously.
  • Instant pain relief.
  • No. 1 pharmacist recommended for toothache relief.

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Product Details

Specifications

Details
Units in Package 1
Unit Size 0.42 oz
Indications Uses: For the temporary relief of pain due to minor irritation or injury of the mouth and gums.
Directions Adult and Children 2 Year of Age and Over: Apply to affected area up to 4 times daily or as directed by a dentist or doctor. Children Between 2 and 12 Years of Age: Ask a doctor before use. Should be supervised in the use of this product. Children Under 2 years of Age: Do not use.
Ingredients Active Ingredients: Benzocaine (20%), Menthol (0.26%), Zinc Chloride (0.15%). Purposes: Oral Pain Reliever, Oral Astringent. Inactive Ingredients: Ammonium Glycyrrhizate, Flavor, PEG-8, PEG-75, Sodium Saccharin, Sorbic Acid, Water.

Reviews From Real Customers

orajel.com
jess.l
christina.v

8. Orajel Severe Toothache & Gum Relief Plus Triple Medicated Gel

Orajel Severe Toothache & Gum Relief Plus Triple Medicated Gel

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Amazon
CTC Health

Product Details

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Jesseg817
Moon child
Painfully Frustrated

9. Red Cross Toothache Medication Drops

Red Cross Toothache Medication Drops

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Product Details

Specifications

Details
Assembled Product Weight 0.8 lb

10. Orajel Pain Reliever Gel, Toothache, Immediate, Regular Strength – 0.25 oz

Orajel Pain Reliever Gel, Toothache, Immediate, Regular Strength - 0.25 oz

  • Provides instant, effective relief from toothache pain
  • The gel form allows users to have more control of product placement during application
  • Orajel toothache gel goes right to the source of the pain for instant relief
  • For the temporary relief of pain due to toothaches

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Midnight Wine & Spirits
Rocklin Bottle Shop

Product Details

Specifications

Details
Units in Package 1
Unit Size 0.25 oz
Indications Temporarily relieves pain due to toothaches.
Directions Do not use if tube tip is cut prior to opening. Cut open tip of tube on score mark. Adults and children 2 years and older: Apply a small amount of product to the cavity and around gum surrounding the teeth. Use up to 4 times daily or as directed by a dentist or doctor. Children under 12 years: Should be supervised in the use of this product. Children under 2 years: Ask a dentist or doctor.
Ingredients Active Ingredient: Benzocaine (10%). Inactive Ingredients: Flavor, Polyethylene Glycol, Sodium Saccharin, Sorbic Acid.

Reviews From Real Customers

kat.t
jessica.g
evangeline.h

11. Orajel Instant Pain Relief, Fast-Acting Gel – 0.125 oz

Orajel Instant Pain Relief, Fast-Acting Gel - 0.125 oz

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Product Details

Specifications

Details
Units in Package 1
Unit Size 0.125 oz
Indications Uses: For the temporary relief of pain due to toothaches. To help protect against infection in minor oral irritation.
Directions Directions: Cut open tip of tube on score mark. Adults and Children 2 Years of Age and Over: Apply a small amount of product to the cavity and around gum surrounding the teeth. Use up to 4 times daily or as directed by a physician or healthcare provider. Children Under 12 Years of Age: Should be supervised in the use of this product. Children Under 2 Years of Age: Ask a physician or healthcare provider.
Ingredients Active Ingredients: Benzocaine (20%), Benzalkonium Chloride (0.1%). Purpose: Oral Pain Reliever, Antiseptic. Inactive Ingredients: Ammonium Glycyrrhizate, Flavor, Polyethylene Glycol, Sodium Saccharin, Sorbic Acid.

12. Orajel Instant Pain Relief for Severe Toothache, Cooling Gel, 0.25 oz by MyOTCStore

Orajel Instant Pain Relief for Severe Toothache, Cooling Gel, 0.25 oz by MyOTCStore

  • This high absorbing formula helps provide a quick relief
  • Formulated to provide temporary relief from toothache
  • The gel form is easy to apply

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CVS Pharmacy

Product Details

Specifications

Details
Product Type Pain reliever
Product Form Gel
Container Type Tube
Recommended Age Group Adult, children

13. Orajel 4X Medicated for Toothache & Gum Cream – 0.33oz

Orajel 4X Medicated for Toothache & Gum Cream - 0.33oz

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Bonanza – Ep Household Llc

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14. Benzodent Dental Pain Relieving Cream Topical Anesthetic 1 Ounce Tube

Benzodent Dental Pain Relieving Cream Topical Anesthetic 1 Ounce Tube

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Paragon Essentials

Product Details

Specifications

Details
Active Ingredients Benzocaine
Item Form Cream
Age Range (Description) 2 years +
Dimensions 1 × 1.06 × 1.13 in

Reviews From Real Customers

Sylvia

15. Equate 4X Medicated Toothache & Gum Relief Oral Pain Gel, 0.25 oz

Equate 4X Medicated Toothache & Gum Relief Oral Pain Gel, 0.25 oz

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Natasha

16. Anbesol Pain Relief, Instant, Maximum Strength, Liquid – 0.41 fl oz

Anbesol Pain Relief, Instant, Maximum Strength, Liquid - 0.41 fl oz

  • 0.41 oz

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Product Details

Specifications

Details
Units in Package 1
Unit Size 0.41 fl oz
Indications Uses: Temporarily relieves pain associated with the following mouth and gum irritations: toothache; sore gums; canker sores; braces; minor dental procedures; dentures..
Directions General directions: See new warnings information. Do not use if plastic blister or backing material is broken or if backing material is separated from plastic. Read and keep card for complete warnings and information. Age group directions: Adults and Children 2 Years of Age and Older:: Wipe liquid on with cotton, or cotton swab, or fingertip. Apply to the affected area up to 4 times daily or as directed by a doctor/dentist. Children Under 12 Years of Age:: Adult supervision should be given in the use of this product. Children Under 2 Years of Age:: Do not use.
Ingredients Active Ingredients: Benzocaine (20 ). Purpose: Oral anesthetic. Inactive Ingredients: Benzyl Alcohol, D&C Yellow 10, FD&C Blue 1, FD&C Red 40, Methylparaben, Natural Flavor, Polyethylene Glycol, Polysorbate 80, Propylene Glycol, Saccharin

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Andronicus
christina.p
Marewartin

17. Hylands 4Kids Oral Pain Relief, 65 mg, Quick-Dissolving Tablets – 125 tablets

Hylands 4Kids Oral Pain Relief, 65 mg, Quick-Dissolving Tablets - 125 tablets

  • Product Description.
  • Natural ReliefHomeopathicToothache, Sensitive Teeth, Sweloling Gums, Oral Discomfort.
  • Product Benefits.
  • Temporarily relieves the symptoms of gum or tooth sensitivity, swelling of gums, tooth and oral pain and discomfort.
  • Ingredients.

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Organic Basic Food

Product Details

Specifications

Details
Units in Package 125
Indications Uses: Temporarily relieves the symptoms of gum or tooth sensitivity, swelling of gums, tooth and oral pain and discomfort.
Directions Directions: Hyland’s Oral Pain Relief Tablets are very soft and will dissolve almost instantly in the mouth. Children 2 Years to Under 6 Years of Age: Dissolve 2 tablets on tongue every 15 minutes for 4 doses, then hourly until relieved. Children 6 Years to Under 12 Years of Age: Dissolve 3 tablets on tongue every 15 minutes for 4 doses, then hourly until relieved. Adults and Children 12 Years and Over: Dissolve 4 tablets on tongue every 15 minutes for 4 doses, then hourly until relieved.
Ingredients Active Ingredients: Arnica Montana 30X HPUS, Calcarea Carbonica 12X HPUS, Calcarea Phospherica 12X HPUS, Chamomilla 12X HPUS, Coffea Cruda 6X HPUS, Ferrum Phosphoricum 12X HPUS. Purpose: Tooth Pain, Sensitive or Swelling Gums, HPUS Indicates That the Active Ingredients Are in the Official Homeopathic Pharmacopoeia of the United States; Tooth Pain, Sensitive Gums or Teeth, HPUS Indicates That the Active Ingredients: Are in the Official Homeopathic Pharmacopoeia of the United States; Sensitive Gums or Teeth, Oral Pain, HPUS Indicates That the Active Ingredients: Are in the Official Homeopathic Pharmacopoeia of the United States; Tooth Pain, Sensitive Gums or Teeth, HPUS Indicates That the Active Ingredients: Are in the Official Homeopathic Pharmacopoeia of the United States; Tooth Pain, Irritability, HPUS Indicates That the Active Ingredients: Are in the Official Homeopathic Pharmacopoeia of the United States; Tooth Pain, Oral Discomfort, Swelling of Gums, HPUS Indicates That the Active Ingredients: Are in the Official Homeopathic Pharmacopoeia of the United States; Inactive Ingredients: Acacia Gum, Lactose.
Warnings Warnings: Do not use: more than directed; if your child has a known allergy to any ingredient in this product. Other warnings: As with any drug, ask a doctor before use if pregnant or breast-feeding. Consult a physician if: symptoms persist for more than 72 hours or worsen; swelling increases, rash or fever develops; irritation, pain or redness persists or worsens. Keep this and all medications out of the reach of children. In case of accidental overdose, contact a medical professional or Poison Control Center immediately. Do not use if imprinted tamper band is broken or missing. In case of emergency, contact a medical professional or Poison Control Center immediately. Hyland’s may also be contacted for emergency information about our products 24 hours a day, 7 days per week at (800) 624-9659.

18. Orajel Dental Gel 5.3g Rapid Toothache Relief

Orajel Dental Gel 5.3g Rapid Toothache Relief

  • Orajel Dental Gel can be used to rapidly relieve the pain caused
  • Broken tooth or a tooth that may require a filling
  • For direct application to the source of toothache
  • Suitable for adults and children 12 years and above

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Neen1973
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janejame-50

19. Orajel Dental Gel 5.3g Rapid Toothache Relief

Orajel Dental Gel 5.3g Rapid Toothache Relief

  • Orajel Dental Gel can be used to rapidly relieve the pain caused
  • Broken tooth or a tooth that may require a filling
  • For direct application to the source of toothache
  • Suitable for adults and children 12 years and above

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Britishonlinesupermarket.com

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20. Orajel Dental Gel for Toothache – 5.3g

Orajel Dental Gel for Toothache - 5.3g

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Conclusion

The conclusion of medicine for tooth and gum pain is that there is no one-size-fits-all solution. There are a variety of over-the-counter and prescription medications that can provide relief, but the best approach depends on the underlying cause of the pain.

In some cases, home remedies may be all that is needed to ease discomfort.

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