When you shop through links on our site, we may earn an affiliate commission. This educational content is not intended to be a substitute for professional advice.

Best Flea And Tick Medicine For Puppies (2024 Updated)

If you’re looking for a way to protect your beloved puppies from fleas and ticks, you’ll be glad to know that there are many flea and tick medicines available on the market. However, with so many options to choose from, choosing the right medicine can be challenging. Before buying, there are several factors you need to consider to ensure that you make the best decision for your furry friends.

First and foremost, you need to think about the age and weight of your puppies. The flea and tick medicines for puppies range from those suitable for young pups to those suitable for adult dogs, so it’s important to choose a product that is age and weight-appropriate. Additionally, you should consider the severity of the flea and tick problem in your area. If there are lots of fleas and ticks, you may need a stronger medication than you would if the problem was less severe.

Before making a purchase, you may have questions about the different flea and tick medications available, such as “what are the active ingredients?” or “how long does the medicine last?” You may also be wondering about the best way to apply the medicine or whether it will irritate your puppy’s skin. All of these are valid concerns, and it’s important to research thoroughly to ensure that you choose the best medicine for your puppies.

10 Best Flea And Tick Medicine For Puppies

# Product Image Product Name Product Notes Check Price
1
This product is ideal for flea and tick prevention and control for small dogs weighing 4-10 lbs, with a 4-month supply.
2
The product is ideal for preventing fleas, ticks, and mosquitoes on dogs of varying sizes through topical treatment.
3
The product is ideal for preventing fleas and ticks in dogs weighing 5-15 lbs with a 3-monthly treatment.
4
The product is ideal for preventing and treating fleas, ticks, and mosquitoes in small dogs weighing between 4-10 pounds.
5
This product is ideal for treating fleas and ticks in small dogs that weigh between 5-22 lbs.
6
The product is ideal for preventing and treating fleas, ticks, and mosquitoes in medium-sized dogs weighing between 11-20 lbs.
7
This product is ideal for preventing and treating fleas, ticks, and mosquitoes on large dogs weighing 21-55 pounds.
8
This product is ideal for preventing and treating flea and tick infestations in small dogs that weigh between 5-22 lbs.
9
Ideal for preventing and treating flea and tick infestations on large dogs weighing 45-88 lbs.
10
This product is ideal for preventing and treating fleas and ticks on dogs over 18 lbs for up to 8 months.
This product is ideal for flea and tick prevention and control for small dogs weighing 4-10 lbs, with a 4-month supply.
The product is ideal for preventing fleas, ticks, and mosquitoes on dogs of varying sizes through topical treatment.
The product is ideal for preventing fleas and ticks in dogs weighing 5-15 lbs with a 3-monthly treatment.
The product is ideal for preventing and treating fleas, ticks, and mosquitoes in small dogs weighing between 4-10 pounds.
This product is ideal for treating fleas and ticks in small dogs that weigh between 5-22 lbs.
The product is ideal for preventing and treating fleas, ticks, and mosquitoes in medium-sized dogs weighing between 11-20 lbs.
This product is ideal for preventing and treating fleas, ticks, and mosquitoes on large dogs weighing 21-55 pounds.
This product is ideal for preventing and treating flea and tick infestations in small dogs that weigh between 5-22 lbs.
Ideal for preventing and treating flea and tick infestations on large dogs weighing 45-88 lbs.
This product is ideal for preventing and treating fleas and ticks on dogs over 18 lbs for up to 8 months.

1. Flea-Free Fido: 4-Month Supply For Small Dogs

TevraPet Activate II for Dogs is a reliable flea and tick control solution that uses Imidacloprid, Permethrin, and Pyriproxyfen, which are the same active ingredients used in K9 Advantix II. This affordable flea and tick treatment includes four monthly doses, providing long-lasting protection.

Veterinarian-approved, TevraPet Activate II actively repels and kills fleas and ticks on contact, ensuring your dog is protected from potential flea-borne illnesses. By breaking the flea life cycle, the insect growth regulator (IGR) in the topical drops starts killing flea eggs and larvae within 12 hours of application, preventing infestations from occurring.

The easy-to-apply solution is designed to be applied to the base of your dog's neck, and it provides continuous protection for up to 30 days per application. The waterproof formula ensures that the solution will remain effective even after your dog gets wet or bathed. TevraPet Activate II is made in the USA to the highest quality standards to ensure your pet's safety.

Pros

  • Uses the same active ingredients as K9 Advantix II
  • Provides long-lasting protection with four monthly doses
  • Actively repels and kills fleas and ticks on contact
  • Prevents infestations by breaking the flea life cycle
  • Easy to apply to the base of your dog's neck
  • Waterproof formula ensures that the solution will remain effective even after your dog gets wet or bathed
  • Made in the USA with the highest quality standards

2. Bug Buster Drops: Protect Your Pooch

The Beloved Pet Armor Plus for Dogs is an advanced formula that has been tried and trusted by many pet owners. It is made with two tough and effective killing ingredients, fipronil and pyriproxyfen, which are similar to the active ingredients found in Frontline Plus and NexGard. Fipronil kills adult fleas and ticks, while pyriproxyfen kills flea eggs and larvae, mosquitoes, and chewing lice. This fast-acting and long-lasting protection is suitable for dogs and puppies 8 weeks and older.

This flea and tick defense kills fleas within 24 hours and ticks within 48 hours. It is effective against all stages of brown dog ticks, American dog ticks, lone star ticks, and deer ticks, including those that may transmit Lyme disease, Rocky Mountain spotted fever, babesiosis, ehrlichiosis, and anaplasmosis.

The Beloved Pet Armor Plus for Dogs also helps break the flea life cycle. It can temporarily suppress flea activity to stop existing infestations and prevent the establishment of new infestations. This product is an excellent replacement for chewable oral pills, collars, tablets, sprays, and chews.

The product is easy to apply and long-lasting. Simply put a single dose of the medication on the dog's skin at the base of the neck, and it will quickly spread over their coat. The waterproof topical treatment provides protection against fleas and ticks for up to three (4) months and prevents re-infestation for up to 4 weeks.

Beloved Pet Armor Plus for Dogs is produced in a GMP facility that is certified to meet the highest safety standards. The product is EPA approved and registered under the Federal Insecticide, Fungicide, and Rodenticide Act. Pet owners can rest assured that they are giving their dogs the highest quality, multi-product possible.

Pros

  • Effective in killing adult fleas and ticks as well as flea eggs and larvae, mosquitoes, and chewing lice.
  • Fast-acting and long-lasting protection for up to three (4) months.
  • Easy to apply and waterproof.
  • Breaks the flea life cycle, preventing the establishment of new infestations.
  • Suitable for dogs and puppies 8 weeks and older.
  • Produced in a GMP facility, certified to meet the highest safety standards.
  • EPA approved and registered under the Federal Insecticide, Fungicide, and Rodenticide Act.

Cons

  • – May cause skin irritation or other adverse reactions in some dogs.
  • – Not suitable for dogs younger than 8 weeks old.
  • – Not suitable for other pets like cats.

3. Hartz 3-Month Flea Defense For Small Dogs

Say goodbye to flea and tick infestations with the fast-acting and patented Pro-cision Flo applicator. This monthly treatment includes 3 easy-to-use, single-dose tubes that penetrate both short and long fur for direct skin application. It is formulated for use on adult dogs and puppies 12 weeks of age and older.

The topical drop formula contains an adulticide that kills fleas, deer ticks, brown dog ticks, and mosquitoes on contact. Additionally, it contains an insect growth regulator (IGR) that prevents flea eggs from hatching, thus breaking the flea life cycle. The treatment provides a comprehensive solution by killing and repelling fleas and ticks for up to 30 days.

The Pro-cision Flo applicator is highly effective in killing flea eggs before they hatch, making it an ideal solution for flea prevention. However, it is important to note that this product is designed for use on dogs only and should not be used on cats or kittens.

This product is an excellent choice for pet owners seeking a fast-acting and reliable flea and tick treatment. It is easy to apply and provides long-lasting protection for your furry friend.

Pros

  • Fast-acting topical drop formula kills fleas, flea eggs, deer ticks, and brown dog ticks, plus repels mosquitoes for 30 days
  • Contains both an adulticide and an insect growth regulator (IGR) for comprehensive flea and tick control
  • Patented Pro-cision Flo applicator easily penetrates short and long fur for direct skin application
  • Provides long-lasting protection for up to 30 days
  • Kills flea eggs before they hatch, breaking the flea life cycle
  • Easy-to-use, single-dose tubes for hassle-free application
  • Ideal for pet owners seeking a reliable flea and tick treatment

Cons

  • – Designed for use on dogs only and should not be used on cats or kittens
  • – May cause skin irritation in some dogs
  • – Requires monthly application for continuous protection

4. Tiny Wonder: Vet-Recommended Flea & Tick Prevention

K9 Advantix II Small Dog 30-day treatment & prevention is a highly effective solution to protect dogs weighing between 4 to 10 lbs. from fleas, ticks, mosquitoes, biting flies, and lice. This vet-recommended formula not only kills fleas within just 12 hours of application but also repels and kills on contact, ensuring that fleas do not need to bite the dog to die. This powerful formula is easy to apply as a topical treatment and is fragrance-free. Moreover, it becomes waterproof after 24 hours, so you don't need to worry about reapplication after your dog takes a bath or goes for a swim. With no prescription required, K9 Advantix II is an affordable and easy-to-use solution to keep your furry friend safe and healthy from pesky parasites all year round.

Protect your small dog from a range of parasites with K9 Advantix II Small Dog 30-day treatment & prevention. This formula is specially designed to safeguard dogs weighing between 4 to 10 lbs. against fleas, ticks, mosquitoes, biting flies, and lice. The vet-recommended formula kills and repels on contact, ensuring that fleas die without biting your dog. The easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours, making it a convenient solution for pet owners. K9 Advantix II Small Dog 30-day treatment & prevention is an affordable and effective way to protect your dog from parasites without the need for a prescription.

K9 Advantix II Small Dog 30-day treatment & prevention is a must-have for small dog owners who want to protect their furry friends from parasites. This veterinary-recommended formula is designed to kill and repel fleas, ticks, mosquitoes, biting flies, and lice quickly and effectively. The fragrance-free topical treatment is easy to apply and becomes waterproof after 24 hours, making it a convenient solution for pet owners. With no prescription required, K9 Advantix II Small Dog 30-day treatment & prevention is an affordable way to keep your dog healthy and happy all year round.

Pros

  • Kills fleas within 12 hours of application
  • Repels and kills on contact, ensuring that fleas do not need to bite the dog to die
  • Easy-to-apply topical treatment
  • Fragrance-free
  • Waterproof after 24 hours
  • No prescription required

5. Frontline Plus For Dogs Flea And Tick Treatment (Small Dog, 5-22 Lbs.) 3 Doses (Orange Box)

FRONTLINE Plus for Dogs is a highly effective and fast-acting flea and tick topical that provides a month-long protection from flea and tick infestations. It is specifically formulated with fipronil and (S)-methoprene to kill adult fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. By breaking the flea life cycle, this product ensures that your dog stays protected from fleas and ticks.

You can trust FRONTLINE Plus to be highly effective in preventing further infestations of fleas and ticks. It is easy to apply with just one monthly dose, and has been trusted by pet owners for over 20 years. It can be used on puppies as young as eight weeks and weighing 5 pounds or more. It has also been formulated to be waterproof, ensuring that it remains effective even after your dog has been in water.

FRONTLINE Plus is also available in a formula designed for cats and kittens that are 8 weeks of age and weigh over 1.5lbs. This makes it easy to protect all the dogs and cats in your house from flea and tick infestations.

To effectively control flea and tick infestations, it is important to treat all dogs or cats in your household monthly. With FRONTLINE Plus, you can ensure that your pets stay protected all year round. Subscribe and save today to make it easier for you to keep your pets protected and never run out of FRONTLINE Plus.

Pros

  • Fast-acting and highly effective flea and tick topical
  • Kills adult fleas, flea eggs, flea larvae, chewing lice, and ticks
  • Trusted by pet owners for over 20 years
  • Waterproof and remains effective even after water exposure
  • Easy to apply with just one monthly dose

Cons

  • – May cause skin irritation in some dogs
  • – May not be effective for all dogs

6. K9 Advantix Ii: Flea, Tick & Mosquito Hero!

The K9 Advantix II Medium Dog 30-day treatment and prevention is a highly effective and vet-recommended solution to protect dogs weighing 11-20 lbs from fleas, ticks, mosquitoes, biting flies, and lice. This product is designed to kill fleas within 12 hours of application, preventing them from biting your dog to die. It is also a repellent, which means that fleas, ticks, and other insects are kept at bay before they even have a chance to bite.

This fragrance-free and waterproof topical treatment is easy to apply, making it a convenient solution for busy pet owners. It requires no prescription, so you can purchase it online or in-store with ease. You can trust K9 Advantix II to protect your furry friend from harmful pests, keeping them healthy and happy for longer.

Pros

  • Highly effective in protecting dogs from fleas, ticks, mosquitoes, biting flies, and lice
  • Kills fleas within 12 hours of application
  • Repels fleas, ticks, and other insects before they can bite
  • Fragrance-free and waterproof after 24 hours
  • Easy-to-apply topical treatment
  • No prescription needed

7. Vet-Recommended Flea Treatment For Large Dogs.

The K9 Advantix II Large Dog 30-day treatment & prevention is an effective solution that protects dogs weighing between 21-55 lbs from fleas, ticks, mosquitoes, biting flies, and lice. This product is highly recommended by vets and is a popular choice among pet owners. The formula kills fleas within 12 hours of application and repels them, so that they do not have to bite your dog and die. This helps to prevent flea infestations and keeps your dog healthy and comfortable.

The easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours, making it convenient for pet owners who want to ensure their dogs stay protected against fleas and ticks. The product does not require a prescription and is safe to use on dogs that are at least 7 weeks old. With regular use, the K9 Advantix II Large Dog 30-day treatment & prevention will keep your dog protected from fleas, ticks, and other harmful insects all year round. It is a cost-effective solution that will save you money in the long run by preventing costly flea infestations and vet bills.

Pros

  • Effective solution that protects dogs from fleas, ticks, mosquitoes, biting flies, and lice
  • Kills fleas within 12 hours of application and repels them
  • Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
  • No prescription needed

Cons

  • – May cause skin irritation in some dogs
  • – May not be suitable for dogs with certain medical conditions

8. Petarmor Plus: Fast-Acting Flea & Tick Defense

PetArmor Plus is a reliable, waterproof flea and tick topical prevention designed for dogs. It is an effective solution that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application, providing long-lasting protection to your furry companion.

This vet quality formula contains the same active ingredients as FRONTLINE Plus for Dogs, fipronil and (S)-methoprene, ensuring a trusted solution to protect your pet from fleas and ticks.

PetArmor Plus works by effectively breaking the flea life cycle, unlike other flea and tick treatments that may only temporarily suppress flea activity. This treatment kills flea eggs and larvae to prevent re-infestation, making it a reliable solution for flea control.

With PetArmor Plus, you can be assured that your pet is protected from fleas and ticks. The fast-acting, long-lasting formula starts killing fleas within 24 hours, and one application lasts up to 30 days. A 6-dose package lasts up to six months, making it a cost-effective solution for flea and tick prevention.

This flea and tick treatment is easy to use and comes with three (3) waterproof topical applications that provide your pet with flea protection and control for three (3) months, ensuring that your dog stays healthy, happy, and free from pesky fleas and ticks.

Pros

  • Effective at killing fleas, flea eggs, flea larvae, ticks, and chewing lice.
  • Contains the same active ingredients as FRONTLINE Plus for Dogs.
  • Breaks the flea life cycle to prevent re-infestation.
  • Fast-acting and long-lasting formula starts killing fleas within 24 hours.
  • One application lasts up to 30 days, and a 6-dose package lasts up to six months.
  • Easy to use and comes with three waterproof topical applications.

9. Frontline Plus For Dogs Flea And Tick Treatment (Large Dog, 45-88 Lbs.) 3 Doses (Purple Box)

Protect your furry friend from fleas and ticks with FRONTLINE Plus for Dogs. This fast-acting, waterproof flea and tick topical is formulated to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease. With fipronil and (S)-methoprene as active ingredients, it kills existing adult fleas, flea eggs, and flea larvae, and prevents further infestations for flea control.

FRONTLINE Plus for Dogs is trusted by pet owners for over 20 years and can be used on puppies as young as eight weeks old, weighing 5 pounds or more. Applying a single monthly dose provides protection from fleas and ticks for 30 days. This formula is also available for cats and kittens over eight weeks of age and weighing 1.5lbs or more, ensuring that all furry companions in your household are protected from flea and tick infestations.

To effectively control fleas and ticks, treat all dogs or cats in your household with FRONTLINE Plus monthly. This will prevent the establishment of new flea infestations and keep your pets protected year-round. Subscribe and save today to ensure that you never run out of FRONTLINE Plus and to make it easier to keep your furry friends protected.

Pros

  • Fast-acting and waterproof formula kills fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
  • Prevents further infestations for flea control
  • Trusted by pet owners for over 20 years
  • Can be used on puppies as young as eight weeks old, weighing 5 pounds or more
  • A single monthly dose provides protection for 30 days
  • Available for cats and kittens over eight weeks of age and weighing 1.5lbs or more

Cons

  • – May cause skin irritation in some pets

10. Vet-Recommended Seresto Collar: Flea & Tick Protection

Introducing Seresto Flea and Tick Collar, a premium flea and tick protection for dogs and puppies that comes vet-recommended without the hefty price tag. This flea collar is designed to kill and repel fleas for eight continuous months, making it a long-lasting choice for pet owners. As the number one selling non-prescription flea and tick brand, it is stocked by over 8,000 vet clinics, according to Elanco Animal Health's data on file.

Seresto Flea and Tick Collar starts working within 24 hours to kill and repel fleas by contact, preventing pests from having to bite your dog to die. This hassle-free, non-greasy, and easy-to-use flea and tick protection ensures your pet is safe and free from flea and tick infestations.

With its premium quality and effectiveness, Seresto Flea and Tick Collar is a must-have for pet owners who want to keep their furry friends healthy and protected from fleas and ticks.

Pros

  • Vet-recommended flea and tick protection
  • Long-lasting for up to eight months
  • Number one selling non-prescription flea and tick brand
  • Effective within 24 hours
  • Hassle-free and non-greasy
  • Easy-to-use

Best Flea And Tick Medicine For Puppies FAQs

At what age can puppies be given flea and tick medicine?

Puppies can usually be given flea and tick medicine at around 8 weeks of age. However, it is important to consult with a veterinarian before administering any medication to your puppy. Flea and tick medication can come in various forms such as topical treatments, collars, and oral medications. It is important to choose the appropriate medication for your puppy's age, weight, and health condition. Fleas and ticks can cause various health problems for your puppy, such as skin irritation, anemia, and even Lyme disease. Therefore, it is crucial to protect your puppy from these parasites. Additionally, regular grooming and cleaning of your puppy's living area can also help prevent flea and tick infestations. Overall, it is important to prioritize your puppy's health and well-being by taking preventative measures against flea and tick infestations.

Can I use human flea and tick medicine on my puppy?

It is not recommended to use human flea and tick medicine on your puppy. This is because human medication is formulated for human physiology and may not be suitable for use on animals. Flea and tick medications designed for humans may cause adverse reactions or side effects in dogs, leading to serious health problems.

It is always best to consult with a veterinarian before administering any medication to your puppy. Your vet will be able to prescribe the right flea and tick medication that is safe and effective for your puppy's age, weight, and breed. They may also recommend preventative measures to avoid future infestations.

Remember, flea and tick infestations can cause serious illnesses and discomfort for your puppy, so it is important to take preventive measures and ensure that they receive proper care. Always seek professional advice before administering any medication to your furry friend.

How frequently should I administer flea and tick medicine for my puppy?

As a responsible pet owner, it's crucial to protect your puppy from flea and tick infestations. These pesky parasites can cause a range of health problems, including skin irritation, anemia, and even transmit diseases. Therefore, it's essential to administer flea and tick medication to your puppy regularly.

The frequency of giving flea and tick medicine to your puppy depends on several factors, such as the medication's type, your puppy's age, lifestyle, and health condition. Generally, flea and tick preventives come in various forms, such as topical solutions, collars, and oral tablets. Each product has a different duration of effectiveness, ranging from a few weeks to several months.

For example, some oral flea and tick medications need to be given once a month, while others may last up to three months. In contrast, topical solutions typically require application every 30 days. Additionally, if your puppy spends a lot of time outdoors, in wooded areas, or with other animals, it may require more frequent treatments.

It's vital to consult with your veterinarian to determine the best flea and tick medication and the optimal frequency of administration for your puppy. Remember to follow the product label instructions, and never give your puppy any medication without a veterinarian's recommendation. By providing your puppy with regular flea and tick medication, you can keep them healthy, happy, and free from pesky parasites.

What are the possible side effects of flea and tick medicine on puppies?

Flea and tick medicine is an essential part of puppy care, as it helps to protect them from these pesky insects. However, like any medication, these treatments can have potential side effects that pet owners should be aware of. Some common side effects of flea and tick medicine on puppies include vomiting, diarrhea, lethargy, and loss of appetite. In rare cases, more severe side effects such as seizures, tremors, and even death can occur. It's important to carefully follow the instructions on the medication and consult with a veterinarian to ensure that the dosage is appropriate for your puppy's age and weight. Additionally, it's important to monitor your puppy for any signs of discomfort or adverse reactions after administering the treatment. If you notice any unusual behavior or symptoms, it's important to contact your veterinarian immediately. Overall, while flea and tick medicine is an important tool in protecting your puppy from these pests, it's important to use it with caution and be mindful of any potential side effects.

What is the safest flea and tick medicine for puppies?

When it comes to choosing a flea and tick medicine for puppies, safety should be the top priority. Puppies' immune systems are not fully developed, making them more vulnerable to harmful chemicals found in some flea and tick products. Therefore, it's essential to select a product that is safe and effective for your puppy.

One of the safest flea and tick medicine for puppies is Frontline Plus. It's a topical medication that kills fleas, ticks, and lice within 24 hours of application. Frontline Plus contains two active ingredients, fipronil and (S)-methoprene, which are safe for puppies over eight weeks old. It's easy to apply and is effective for up to 30 days.

Another safe option is NexGard, an oral medication that kills fleas and ticks. It's also effective against the Lone Star tick, which is common in some regions. NexGard contains afoxolaner, which is safe for puppies over eight weeks old. It's easy to administer and is effective for up to 30 days.

However, it's always best to consult with your veterinarian before giving any medication to your puppy. They can recommend the best flea and tick medicine for your puppy based on their age, weight, and overall health.

Leave a Comment