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20 Best Eye Drops For Chronic Dry Eye (2022 Updated)

There are several different types of eye drops that can be used to treat chronic dry eye. Artificial tears are the most common type of eye drop used to treat this condition. They can help to lubricate the eyes and reduce the symptoms of dry eye.

Other types of eye drops that may be used include anti-inflammatory eye drops, eye ointments, and lubricating gels.

20 Best Eye Drops For Chronic Dry Eye

Product Image Product Name Features Price

Alcon Bion Tears Eye Drops, Lubricant, Severe Dry Eye, Single-Use Vials – 28 pack …

  • Relieves dryness of the eye.
  • Temporarily relieves the burning and irritation from dry eyes.
  • Mimics the composition of human tears.

Refresh Tears Lubricant Eye Drops

  • For temporary relief of burning, itching and discomfort due to dryness of the eye or exposure to wind or sun
  • May be used as a protectant against further irritation

Thera Tears Lubricant Eye Drops – 1 fl oz bottle

  • 1 Fl Oz

Ocusoft Retaine MGD Complete Dry Eye Relief Lubricant Eye Drops – 30 count, 0.01 …

  • Preservation-free
  • Relieves irritation
  • Long-lasting comfort

Similasan iVizia Eye Drops, Lubricant, Sterile, For Dry Eyes – 0.16 fl oz

  • 0.16 Fl Oz

Refresh Tears Lubricant Eye Drops – 2 pack, 0.5 fl oz droppers

  • Original strength formula.
  • Relieves mild symptoms of eye dryness.
  • Instantly moisturizes and lubricates.

Blink Tears Lubricating Eye Drops – 0.5 fl oz bottle

  • 0.5 Fl Oz

Visine Dry Eye Relief Lubricant Eye Drops – 0.5 fl oz bottle

  • Soothes dry eyes
  • Includes ingredients found in natural tears
  • Contains glycerin, hypromellose, and polyethylene glycol 400

Systane Complete Eye Drops Eye Drops, 10 Ml

  • 10 ml

Systane Ultra Lubricant Eye Drops 60

  • 60 Ct

Similasan Eye Drops, Dry Eye Relief, Sterile – 10 ml

  • Relieves symptoms of dry eye
  • For redness of eyes and lids
  • Helps with reflex watering

GenTeal Lubricant Eye Drops Moderate – .5 FL OZ

  • Moderate dry eye symptom relief
  • Fast soothing relief
  • Quick relief from moderate irritation and discomfort

Refresh Optive Lubricant Eye Drops – 0.5 fl oz bottle

  • For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun
  • Effectively relieves dry eye symptoms that may occur following Lasik surgery

Refresh Eye Drops, Lubricant, Classic, Single-Use Containers – 50 pack, 0.01 fl oz containers

  • Computer use and reading
  • Wind and sun
  • Certain medications

HYLO-GEL Eye Drops 10ml

  • DUAL provides protection againstenvironmental allergens and relief for itching and burning eyes.
  • DUAL eye drops are suitable for adults andchildren from the age of 6 years and can also be used during pregnancy andbreast-feeding.

Vizulize Intense Dry Eye Drops 10ml

  • Formulated to be naturally kind to eyes, Vizulize Intensive Dry Eye Drops are pH balanced to the eye’s tear fluid so as not to sting on application.

Refresh Optive Advanced Lubricant Eye Drops

  • Doctor recommended artificial tear brand.
  • Delivers innovative, triple action, lipid-enhanced tear provides the low blur and comfort of an aqueous tear.

Optiben Irritated Eyes Sterile Eye Dryness Bottle 15ml

  • Dry Eye (Bottle 15 ml ) prepared eye that moisturizes and refreshes the eye.Features: Optiben Irritated Eyes Sterile.
  • Hypromellose or HPMC (Methocel E4 Premium /Methocel F4M Premium) Buy Optiben Irritated Eyes Sterile.
Alcon Bion Tears Eye Drops, Lubricant, Severe Dry Eye, Single-Use Vials – 28 pack …
  • Relieves dryness of the eye.
  • Temporarily relieves the burning and irritation from dry eyes.
  • Mimics the composition of human tears.
Refresh Tears Lubricant Eye Drops
  • For temporary relief of burning, itching and discomfort due to dryness of the eye or exposure to wind or sun
  • May be used as a protectant against further irritation
Thera Tears Lubricant Eye Drops – 1 fl oz bottle
  • 1 Fl Oz
Ocusoft Retaine MGD Complete Dry Eye Relief Lubricant Eye Drops – 30 count, 0.01 …
  • Preservation-free
  • Relieves irritation
  • Long-lasting comfort
Similasan iVizia Eye Drops, Lubricant, Sterile, For Dry Eyes – 0.16 fl oz
  • 0.16 Fl Oz
Refresh Tears Lubricant Eye Drops – 2 pack, 0.5 fl oz droppers
  • Original strength formula.
  • Relieves mild symptoms of eye dryness.
  • Instantly moisturizes and lubricates.
Blink Tears Lubricating Eye Drops – 0.5 fl oz bottle
  • 0.5 Fl Oz
Visine Dry Eye Relief Lubricant Eye Drops – 0.5 fl oz bottle
  • Soothes dry eyes
  • Includes ingredients found in natural tears
  • Contains glycerin, hypromellose, and polyethylene glycol 400
Systane Complete Eye Drops Eye Drops, 10 Ml
  • 10 ml
Systane Ultra Lubricant Eye Drops 60
  • 60 Ct
Similasan Eye Drops, Dry Eye Relief, Sterile – 10 ml
  • Relieves symptoms of dry eye
  • For redness of eyes and lids
  • Helps with reflex watering
GenTeal Lubricant Eye Drops Moderate – .5 FL OZ
  • Moderate dry eye symptom relief
  • Fast soothing relief
  • Quick relief from moderate irritation and discomfort
Refresh Optive Lubricant Eye Drops – 0.5 fl oz bottle
  • For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun
  • Effectively relieves dry eye symptoms that may occur following Lasik surgery
Refresh Eye Drops, Lubricant, Classic, Single-Use Containers – 50 pack, 0.01 fl oz containers
  • Computer use and reading
  • Wind and sun
  • Certain medications
HYLO-GEL Eye Drops 10ml
  • DUAL provides protection againstenvironmental allergens and relief for itching and burning eyes.
  • DUAL eye drops are suitable for adults andchildren from the age of 6 years and can also be used during pregnancy andbreast-feeding.
Vizulize Intense Dry Eye Drops 10ml
  • Formulated to be naturally kind to eyes, Vizulize Intensive Dry Eye Drops are pH balanced to the eye’s tear fluid so as not to sting on application.
Refresh Optive Advanced Lubricant Eye Drops
  • Doctor recommended artificial tear brand.
  • Delivers innovative, triple action, lipid-enhanced tear provides the low blur and comfort of an aqueous tear.
Optiben Irritated Eyes Sterile Eye Dryness Bottle 15ml
  • Dry Eye (Bottle 15 ml ) prepared eye that moisturizes and refreshes the eye.Features: Optiben Irritated Eyes Sterile.
  • Hypromellose or HPMC (Methocel E4 Premium /Methocel F4M Premium) Buy Optiben Irritated Eyes Sterile.

1. Alcon Bion Tears Eye Drops, Lubricant, Severe Dry Eye, Single-Use Vials – 28 pack …

Alcon Bion Tears Eye Drops, Lubricant, Severe Dry Eye, Single-Use Vials - 28 pack ...

  • Relieves dryness of the eye.
  • Temporarily relieves the burning and irritation from dry eyes.
  • Mimics the composition of human tears.
  • Helps restore the eye to its natural environment, making it one of the most effective artificial tea.

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Product Details

Specifications

Details
Units in Package 28
Unit Size 0.015 fl oz vials
Indications Uses: For use as a protectant against further irritation or to relieve dryness of the eye.
Directions Directions: Make sure container is intact before use. To open, completely twist off tab. Do not pull off. Instill 1 or 2 drops in the affected eye(s) as needed. Throw away container. Do not reuse. Once opened, discard. All four containers within a pouch must be used within four days of opening the pouch. Instill 1 or 2 drops in the affected eye(s) as needed.
Ingredients Active Ingredients: Dextran 70 (0.1%), Hypromellose 2910 (0.3%). Purpose: Lubricant, Lubricant. Inactive Ingredients: Calcium Chloride, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Bicarbonate, Sodium Chloride, Zinc Chloride, Hydrochloric Acid and/or Sodium Hydroxide and/or Carbon Dioxide to Adjust pH.
Warnings Warnings: For external use only. Do not use: if this solution changes color or becomes cloudy; if you are sensitive to any ingredient in this product. When using this product: to avoid contamination, do not touch tip of container to any surface; do not touch unit-dose tip to eye; do not reuse (Once opened, discard). Stop use and ask a doctor if: you experience eye pain; changes in vision; continued redness; irritation of the eye; symptoms worsening or persisting for more than 72 hours. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away. Other warnings: Tamper Evident: Containers are sealed in a protective foil pouch. Use only if foil pouch is undamaged at time of purchase.

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Margo N.
Zaklina i.
VSHMI

2. Refresh Tears Lubricant Eye Drops

Refresh Tears Lubricant Eye Drops

  • For temporary relief of burning, itching and discomfort due to dryness of the eye or exposure to wind or sun
  • May be used as a protectant against further irritation
  • More bottles for more places

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Specifications

Details
Ingredients Active Ingredient: Carboxymethylcellulose Sodium 0.5%…Purpose: Eye Lubricant. Inactive: Boric Acid, Calcium Chloride, Magnesium Chloride, Potassium Chloride, Purified Water, Purite (Stabilized Oxychloro Complex), Sodium Borate, and Sodium Chloride. May Also Contain Hydrochloric Acid and/Or Sodium Hydroxide to Adjust Ph.
Units in Package 1
Unit Size 2.17 fl oz box

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amanzione
erica.m

3. Thera Tears Lubricant Eye Drops – 1 fl oz bottle

Thera Tears Lubricant Eye Drops - 1 fl oz bottle

  • 1 Fl Oz

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Details
Units in Package 1
Unit Size 1 fl oz
Indications Uses: As a lubricant to relieve dryness of the eye. As a protectant against further irritation of the eye. For temporary relief of burning, irritation, and discomfort including exposure to wind or sun.
Directions General directions: Instill 1 or 2 drops in the affected eye(s) as needed.
Ingredients Active Ingredients: Sodium Carboxymethylcellulose (0.25 %). Purpose: Eye Lubricant. Inactive Ingredients: Borate Buffers, Calcium Chloride, Dequest, Magnesium Chloride, Potassium Chloride, Sodium Bicarbonate, Sodium Chloride, Sodium Perborate, Sodium Phosphate, and Water for Injection

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AdrianPB
MILDRED
amber.h

4. Ocusoft Retaine MGD Complete Dry Eye Relief Lubricant Eye Drops – 30 count, 0.01 …

Ocusoft Retaine MGD Complete Dry Eye Relief Lubricant Eye Drops - 30 count, 0.01 ...

  • Preservation-free
  • Relieves irritation
  • Long-lasting comfort

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Dryeye Rescue

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Specifications

Details
Units in Package 30
Unit Size 0.01 fl oz sterile
Indications Uses: For use as a protectant against further irritation or to relieve dryness of the eye .
Directions General directions: Shake well before using. Instill 1 or 2 drops in the affected eye(s) as needed and discard container.
Ingredients Active Ingredients: Light Mineral Oil (0.5 %), Mineral Oil (0.5 %). Purpose: Emollient, Emollient. Inactive Ingredients: Cetalkonium Chloride, Glycerol, Poloxamer 188, Tris Hydrochloride, Tromethamine, Tyloxapol, Water for Injection.
Warnings Use only if twist top of single-dose container is intact. For use in the eyes only. Do not use if this product changes color.. When using this product do not touch tip of container to any surface to avoid contamination, do not reuse once opened.. Stop use and ask a doctor if you feel eye pain or changes in vision, continue redness or irritation of the eye, the condition worsens or persists for more than 72 hours.. Keep out of the reach of children. If swallowed, get medical help or contact a Poison Control Center immediately. Use only if twist top of single-dose container is intact.

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amkarei
Creek House

5. Refresh Plus Lubricant Single-Use Eye Drops – 100 ct, 0.01 fl oz vials

Refresh Plus Lubricant Single-Use Eye Drops - 100 ct, 0.01 fl oz vials

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Specifications

Details
Ingredients Active Ingredient: Carboxymethylcellulose Sodium 0.5%…Purpose: Eye Lubricant. Inactive Ingredients: Calcium Chloride, Magnesium Chloride; Potassium Chloride; Purified Water, Sodium Chloride, and Sodium Lactate. May Also Contain Hydrochloric Acid and/Or Sodium Hydroxide to Adjust Ph.
Units in Package 100

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C
Lucy
Sandrar

6. Similasan iVizia Eye Drops, Lubricant, Sterile, For Dry Eyes – 0.16 fl oz

Similasan iVizia Eye Drops, Lubricant, Sterile, For Dry Eyes - 0.16 fl oz

  • 0.16 Fl Oz

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Specifications

Details
Units in Package 1
Unit Size 0.16 fl oz
Indications Uses: (one or more of these) For the temporary relief of burning and irritation due to dryness of the eye; For the temporary relief of discomfort due to minor irritations of the eye or to exposure to wind and sun; For use as a protectant against further irritation or to relieve dryness of the eye; For use as a lubricant to prevent further irritation or to relieve dryness of the eye..
Directions General directions: Wash hands well before use. Instill 1 or 2 drops in the affected eye(s) as needed. Can be used when wearing contact lenses. To limit blurriness when using contact lenses: remove contacts, apply drops, then insert contacts.
Ingredients Active Ingredients: Povidone (0.5 %). Purpose: Eye Lubricant. Inactive Ingredients: Hydrochloric Acid, Purified Water, Sodium Chloride, Sodium Hyaluronate, Trehalose, Tromethamine

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Kvetch
Lynn Evans
Terry Kristofak

7. Refresh Tears Lubricant Eye Drops – 2 pack, 0.5 fl oz droppers

Refresh Tears Lubricant Eye Drops - 2 pack, 0.5 fl oz droppers

  • Original strength formula.
  • Relieves mild symptoms of eye dryness.
  • Instantly moisturizes and lubricates.
  • Designed to act like your own natural tears.
  • Doctor recommended with over 30 years of experience; REFRESH Family of Products, Ipsos Healthcare, 2021 REFRESH ECP Recommendation Survey.

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Specifications

Details
Ingredients Active: Carboxymethylcellulose Sodium 0.5%…Purpose: Eye Lubricant. Inactive: Boric Acid, Calcium Chloride, Magnesium, Potassium Chloride, Purified Water, Purite (Stabilized Oxychloro Complex), Sodium Borate and Sodium Chloride. May Also Contain Hydrochloric Acid and/Or Sodium Hydroxide to Adjust Ph.

8. Blink Tears Lubricating Eye Drops – 0.5 fl oz bottle

Blink Tears Lubricating Eye Drops - 0.5 fl oz bottle

  • 0.5 Fl Oz

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Specifications

Details
Units in Package 1
Unit Size 0.5 fl oz
Indications Uses: For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation..
Directions Discard solution 90 days after opening. General directions: Instill 1 or 2 drops in the affected eye(s) as needed or as directed by your eye care professional.
Ingredients Active Ingredients: Polyethylene Glycol 400 (0.25 %). Purpose: Eye lubricant. Inactive Ingredients: Boric Acid, Calcium Chloride, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Borate, Sodium Chloride, Sodium Chlorite (OcuPure Brand) as a Preservative, Sodium Hyaluronate

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Robin
leeann.k
lena.b

9. Visine Dry Eye Relief Lubricant Eye Drops – 0.5 fl oz bottle

Visine Dry Eye Relief Lubricant Eye Drops - 0.5 fl oz bottle

  • Soothes dry eyes
  • Includes ingredients found in natural tears
  • Contains glycerin, hypromellose, and polyethylene glycol 400
  • Relieves burning and irritation from dryness
  • Protects against further irritation

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Specifications

Details
Units in Package 1
Unit Size 0.5 fl oz
Indications Uses: For the temporary relief or burning, irritation and discomfort due to dryness of the eye exposure to wind or sun. For protection against further irritation.
Directions Age group directions: Adults and Children 6 Years of Age and Over: 1 or 2 drops in the affected eye(s) as needed, Children Under 6 Years of Age: Consult a doctor.
Ingredients Active Ingredients: Polyethylene Glycol 400 (1 %). Purpose: Lubricant. Inactive Ingredients: Ascorbic Acid, Benzalkonium Chloride, Boric Acid, Dextrose, Disodium Phosphate, Glycerin, Glycine, Hypromellose, Magnesium Chloride, Potassium Chloride, Purified Water, Sodium Borate, Sodium Chloride, Sodium Citrate, Sodium Lactate

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nehal .p
Peek
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10. Systane Complete Eye Drops Eye Drops, 10 Ml

Systane Complete Eye Drops Eye Drops, 10 Ml

  • 10 ml

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Details
Length 1.25″
Width 1.75″
Height 3.88″
Product Weight 0.33 fluid oz
Product Form Drops

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11. Systane Ultra Lubricant Eye Drops 60

Systane Ultra Lubricant Eye Drops 60

  • 60 Ct

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Specifications

Details
Purpose Lubricant
Preservative-Free Yes
Product Form Drops
Net Volume 0.7 ml
Net Weight 0.02 oz

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Cassandra Rose

12. Similasan Eye Drops, Dry Eye Relief, Sterile – 10 ml

Similasan Eye Drops, Dry Eye Relief, Sterile - 10 ml

  • Relieves symptoms of dry eye
  • For redness of eyes and lids
  • Helps with reflex watering

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Units in Package 1
Unit Size 0.33 fl oz
Indications Uses: According to homeopathic principles, the active ingredients in this product temporarily relieve minor symptoms such as: dry eye; redness of eyes and lids; reflex watering secondary to dry eye.
Directions Age group directions: For Adults and Children Age 2 and Over: Remove tamper-evident seal from neck of bottle. Twist cap off bottle. Don’t squeeze bottle, squeeze plastic tip to release 1 to 2 drops into eye. Apply as needed. Replace cap after use.
Ingredients Active Ingredients: Belladonna 6X, Euphrasia Officinalis (Eyebright) 6X, Mercurius Sublimatus 15X. Purpose: Dryness, Redness, Containing 0.0000002% Alkaloids Calculated as Hyoscyamine., Redness, Dryness. Inactive Ingredients: Borate Buffer, Purified Water, Silver Sulfate (as Preservative), Sodium Nitrate

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13. Refresh Tears Multi-Pack, 60 ml.

Refresh Tears Multi-Pack, 60 ml.

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14. GenTeal Lubricant Eye Drops Moderate – .5 FL OZ

GenTeal Lubricant Eye Drops Moderate - .5 FL OZ

  • Moderate dry eye symptom relief
  • Fast soothing relief
  • Quick relief from moderate irritation and discomfort
  • Provides relief from moderate irritation and discomfort caused by dry eye symptoms
  • Previously tears natural forte

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Specifications

Details
Country/Region of Manufacture United States
Dosage 3 mg
Formulation Drops
Main Purpose Eye Health
Ingredients Dextran

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15. Refresh Optive Lubricant Eye Drops – 0.5 fl oz bottle

Refresh Optive Lubricant Eye Drops - 0.5 fl oz bottle

  • For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun
  • Effectively relieves dry eye symptoms that may occur following Lasik surgery
  • Preservative free

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Details
Units in Package 1
Unit Size 0.5 fl oz
Indications Uses: For the temporary relief of burning, irritation. and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.
Directions General directions: Instill 1 or 2 drops in the eye(s) as needed.
Ingredients Active Ingredients: Carboxymethylcellulose Sodium (0.5 %), Glycerin (0.9 %). Purpose: Eye Lubricant, Eye Lubricant. Inactive Ingredients: Boric Acid, Calcium Chloride Dihydrate, Erythritol, Levocarnitine, Magnesium Chloride Hexahydrate, Potassium Chloride, Purified Water, Purite (Stabilized Oxychloro Complex), Sodium Borate Decahydrate, Sodium Citrate Dihydrate

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16. Refresh Eye Drops, Lubricant, Classic, Single-Use Containers – 50 pack, 0.01 fl oz containers

Refresh Eye Drops, Lubricant, Classic, Single-Use Containers - 50 pack, 0.01 fl oz containers

  • Computer use and reading
  • Wind and sun
  • Certain medications
  • Natural aging process
  • Heating and air conditioning

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Units in Package 50
Unit Size 0.01 fl oz containers
Indications Uses: For the temporary relief of burning, irritation, and discomfort due to dryness of the eye or exposure to wind or sun. May be used as a protectant against further irritation.
Directions Directions: How to Use: To open, twist and pull tab to remove. Instill 1 or 2 drops in the affected eye(s) as needed and discard container.
Ingredients Active Ingredients: Polyvinyl Alcohol (1.4%), Povidone (0.6%). Purpose: Eye Lubricant, Eye Lubricant. Inactive Ingredients: Purified Water and Sodium Chloride. May Also Contain Hydrochloric Acid and/or Sodium Hydroxide to Adjust pH.

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maysaa.d
meansugar.m
betty.r

17. HYLO-GEL Eye Drops 10ml

HYLO-GEL Eye Drops 10ml

  • DUAL provides protection againstenvironmental allergens and relief for itching and burning eyes.
  • DUAL eye drops are suitable for adults andchildren from the age of 6 years and can also be used during pregnancy andbreast-feeding.
  • How should HYLO.
  • DUALshould be applied 3 times a day but it can be used more often withouthesitation in cases of more serious discomfort.

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Details
Product Dimensions 4.41 x 2.48 x 0.51 inches

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18. Vizulize Intense Dry Eye Drops 10ml

Vizulize Intense Dry Eye Drops 10ml

  • Formulated to be naturally kind to eyes, Vizulize Intensive Dry Eye Drops are pH balanced to the eye’s tear fluid so as not to sting on application.
  • Like all Vizulize eye care products, Vizulize Intensive Dry Eye Drops can be safely used with contact lenses without having to remove them.
  • Conditions treated.

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lea2186
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19. Refresh Optive Advanced Lubricant Eye Drops

Refresh Optive Advanced Lubricant Eye Drops

  • Doctor recommended artificial tear brand.
  • Delivers innovative, triple action, lipid-enhanced tear provides the low blur and comfort of an aqueous tear.
  • No shaking required.
  • Safe to use as often as needed.

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Details
Units in Package 2
Unit Size 0.33 fl oz bottles
Recommended Age Group Adult

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Chaibok
AK

20. Optiben Irritated Eyes Sterile Eye Dryness Bottle 15ml

Optiben Irritated Eyes Sterile Eye Dryness Bottle 15ml

  • Dry Eye (Bottle 15 ml ) prepared eye that moisturizes and refreshes the eye.Features: Optiben Irritated Eyes Sterile.
  • Hypromellose or HPMC (Methocel E4 Premium /Methocel F4M Premium) Buy Optiben Irritated Eyes Sterile.
  • Dry Eye (Bottle 15 ml Online at the best price on farmaciagt.

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Conclusion

As the best eye drop for chronic dry eye may vary depending on the individual’s specific condition. However, some common options for chronic dry eye relief include artificial tears, gels, ointments, and punctal plugs.

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