If you’re looking for the best toothache pain reliever over the counter, there are a few factors you should consider before making a purchase. First and foremost, you'll want to identify the specific cause of your toothache, as different products may be more effective depending on the root of the problem. For instance, if your toothache is caused by sensitivity, a toothpaste designed for sensitive teeth may be more effective than a traditional pain reliever. Additionally, you'll want to consider the severity of your toothache and the duration of relief you require. A product may work well for mild pain, but if you’re experiencing severe discomfort, you may need a stronger solution.
When looking for a toothache pain reliever, some potential questions that come to mind are: What are the active ingredients in the product? How long does the relief typically last? Are there any potential side effects or interactions with other medications? Are there any other symptoms, such as fever or swelling, that signal a dental emergency? Ultimately, finding the best toothache pain reliever over the counter involves carefully weighing these factors and ensuring that the product you choose is safe and effective for your specific needs. By considering these factors and doing your research, you can find a toothache pain reliever that provides the relief you need to get back to your daily routine.
10 Best Toothache Pain Reliever Over Counter
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The product is ideal for relieving arthritis pain and reducing fever.
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2
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It is an ideal pain relief and fever reducer medication with 500mg acetaminophen caplets, sold in a 400-count bottle.
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3
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This product is ideal for providing relief from pain, fever, body aches, headaches, arthritis pain, and more.
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4
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Ideal for pain relief and sleep aid with a combination of Ibuprofen and Diphenhydramine HCL in liquid-filled capsules.
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5
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Ideal for providing pain relief, reducing fever, and treating aches. Comes in travel-size packs for convenience.
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6
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It is an over-the-counter pain reliever and fever reducer for various types of pain such as arthritis, toothache and backache.
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7
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It is an NSAID pain reliever and fever reducer recommended by orthopedic surgeons, available in a 270 count.
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8
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The product is ideal for relieving pain and reducing fever, while also providing nighttime sleep aid.
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9
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The product is ideal for relieving pain and discomfort quickly and efficiently.
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10
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It is ideal for relieving pain and reducing fever as it is a nonsteroidal anti-inflammatory drug (NSAID).
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1. Tylenol Arthritis Pain Caplets – 290 Ct

Introducing the innovative bi-layer caplets designed to provide fast-acting relief from arthritis pain! These caplets are a game-changer for anyone seeking temporary relief from minor arthritis pain. Each caplet contains a powerful 650 milligrams of acetaminophen, a well-known pain-relieving agent that has been trusted for decades.
The bi-layer design of these caplets ensures that the pain relief is delivered quickly and lasts for up to eight hours. So, you can say goodbye to the constant struggle of dealing with arthritis pain throughout the day.
These caplets are manufactured by Tylenol, a brand that is highly recommended by doctors and trusted by millions of people worldwide. You can rely on the quality and effectiveness of these caplets to provide you with the relief you need to get back to your daily routine.
2. Rapid Relief Extra Strength Pain And Fever.

The Amazon Basic Care Rapid Release Acetaminophen 500 mg Caplets are a powerful pain reliever and fever reducer. With 500 mg of acetaminophen as its active ingredient, it compares to the Tylenol Extra Strength Rapid Release Gels active ingredient. These caplets offer fast relief from minor aches and pains associated with headache, muscular aches, backache, minor pain of arthritis, the common cold, toothache, and premenstrual and menstrual cramps. The product is also effective at temporarily reducing fever.
This extra strength formula is designed for adults and children ages 12 years and over. The package features a child-resistant cap to keep little ones safe. Each caplet contains 500 mg of acetaminophen, making it a potent solution for those seeking fast relief.
One of the unique features of the Amazon Basic Care Rapid Release Acetaminophen 500 mg Caplets is that they are gluten-free. The product is also free of aspirin and caffeine, making it a suitable choice for those with dietary restrictions or sensitivities.
3. Ibuprofen 200 Mg, 500-Count Pain Reliever

The Amazon Basic Care Ibuprofen Tablets 200 mg is a non-prescription pain reliever and fever reducer that contains ibuprofen 200 mg as its active ingredient. This product is formulated to provide effective pain relief for tough pain, including muscular aches, minor arthritis pain, toothache, backache, menstrual cramps, and minor aches and pains from the common cold. It also temporarily reduces fever.
The Amazon Basic Care Ibuprofen Tablets 200 mg is proven to be strong on tough pain, helping individuals get the relief they need to keep going. This pain reliever and fever reducer is effective for adults and children 12 years and older, and it provides a convenient solution for those who need pain relief without a prescription.
The coated Amazon Basic Care Ibuprofen Tablets 200 mg is known for its proven pain relief, making it a go-to choice when pain tries to take over. It is formulated with the number one doctor recommended back pain OTC active ingredient, which was determined through a survey of U.S. physicians by an independent market research firm.
4. Advil Pm: Sleep & Pain Relief Capsules

The Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid is a reliable and effective solution for occasional sleeplessness related to minor aches and pains. This package contains two bottles of 80 liquid-filled capsules each. It is a pain medicine that contains Ibuprofen and Diphenhydramine HCL, which helps in pain relief and sleep aid.
With its Ibuprofen PM formula, this medication can help relieve headache, minor arthritis pain, back pain, and other types of pain that may keep one up at night. It delivers liquid relief right where it is needed, ensuring that the user experiences fast pain relief.
The Advil PM Liqui-Gels Pain Reliever also doubles as a nighttime sleep aid. It is specially formulated to help users fall asleep and stay asleep, giving them the rest they need to wake up feeling refreshed and rejuvenated. This makes it an excellent choice for those who struggle with occasional sleeplessness.
By 2022, the Advil PM Liqui-Gels Pain Reliever and Nighttime Sleep Aid will feature new packaging that is 20% less plastic, which means nearly 500,000 pounds of plastic will be kept out of landfills. This shows that the company is committed to reducing its carbon footprint and promoting environmental sustainability.
This medication is suitable for both adults and children who are 12 years and older. To use, take two Advil PM Liqui-Gels Pain Reliever capsules at bedtime for occasional sleeplessness related to minor aches and pains. It is essential to read and follow the instructions on the label carefully.
5. Motrin Ib, Ibuprofen 200mg Tablets For Fever, Aches & Pain Relief, 50 Travel Packs Of 2, 100 Ct

Motrin IB Tablets are your reliable partner in providing temporary pain relief from minor aches and pains. With 50 individual packs of 2-count tablets, you can conveniently take control of your pain even while on-the-go.
These tablets contain 200 milligrams of ibuprofen pain relief medicine that works quickly to stop pain at its source. Whether it's due to a common cold, minor pain of arthritis, headache, backache, toothache, or menstrual cramps, Motrin IB Tablets offer powerful pain relief that lasts.
In addition to pain relief, these tablets also help temporarily reduce fever. Motrin IB Tablets are safe and effective for ages 12 years or older when used as directed for fever and pain relief.
So why let pain hinder you from doing your daily activities? Take one Motrin IB Tablet today and experience long-lasting pain relief.
6. Basic Care Ibuprofen: Pain & Fever Relief (100ct)

Amazon Basic Care Ibuprofen Tablets provide temporary relief for minor aches and pains, as well as fever reduction. Each coated caplet contains 200mg of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID), making it comparable to the active ingredient found in Motrin IB.
These orange-coated caplets are gluten-free and provide relief for headaches, muscular aches, minor arthritis pain, toothaches, backaches, menstrual cramps and the common cold. The caplets are designed for adults and children aged 12 years and over. However, if you are considering giving it to a child under 12 years of age, it is important to consult a doctor before use.
The package is child-resistant, providing an added layer of safety. Additionally, the product is gluten-free, making it a suitable choice for those with gluten sensitivities.
Amazon Basic Care Ibuprofen Tablets provide fast-acting relief for minor aches and pains, allowing you to continue your day without being distracted by discomfort. The coated caplets are easy to swallow, making it a convenient choice for those on the go.
7. Orthofever – Aleve Caplets, 270 Count

Aleve is a nonsteroidal anti-inflammatory drug (NSAID) that is available over-the-counter (OTC). It has been clinically proven to be stronger and longer-lasting on pain than Tylenol, based on data from the first six hours after initial dosing. With just two pills, Aleve can provide all-day relief from pain. Each pill is designed to last for up to 12 hours.
Aleve is the number one OTC brand for minor arthritis pain, as recommended by orthopedic surgeons. This medication is specifically designed to deliver up to 12 hours of continuous pain relief directly to the site of pain.
Aleve provides temporary relief for a variety of minor aches and pains, including backaches, muscular aches, headaches, minor arthritis and other joint pain, menstrual pain, and toothaches. It also has the added benefit of temporarily reducing fever.
8. Advil Double Relief: Day And Night Combo

The Advil Pain Reliever and Fever Reducer Coated Tablets and Advil PM Pain Reliever and Nighttime Sleep Aid Caplets are a package deal that offers comprehensive pain relief and a restful night's sleep. The package includes a 300 count bottle of the Advil Pain Reliever and Fever Reducer Coated Tablets and a 2 count pack of Advil PM Pain Reliever and Nighttime Sleep Aid Caplets.
The Advil ibuprofen 200mg pain reliever is a versatile medication that can help manage different kinds of pain like headache, arthritis, and back pain. The new packaging now features 20% less plastic, which translates to nearly 500,000 pounds of plastic saved from landfills.
The coated Advil ibuprofen pain reliever tablets are designed for adults and children 12 years and older, and they are easy to swallow. The relief provided by the medication can last for up to 6 hours, ensuring that you get long-lasting relief from your pain.
Advil PM Nighttime Pain Reliever caplets are ideal for those who have trouble sleeping due to minor aches and pains. These caplets will help you fall asleep and stay asleep, enabling your body to heal as you rest. The Ibuprofen PM provides headache relief, arthritis pain relief, and joint pain relief. It also helps relieve occasional sleeplessness related to minor aches and pains, so you can wake up feeling refreshed and rejuvenated.
9. Bc Powder Original Strength Pain Reliever, Aspirin Dissolve Packs, 50 Count

Introducing BC Original Strength Powder Pain Reliever, a powerful and effective solution for adults seeking fast relief from various types of pain. This specially formulated powder pain reliever works quickly to alleviate headaches, backaches, toothaches, muscle aches, and menstrual cramps.
The dual-action formula of BC Original Strength Powder Pain Reliever is designed to provide fast and effective relief from pain. It contains Aspirin, 845 mg (NSAID), and Caffeine, 65 mg, which work together to tackle pain quickly and efficiently. The powder form of this pain reliever dissolves faster than pills, making it a convenient option for those seeking fast-acting pain relief.
BC Original Strength Powder Pain Reliever comes in convenient, single-serving dissolve packs, making it easy to take on-the-go. Simply pour the contents of one packet into water or your favorite beverage, and within minutes, you'll experience relief from your pain.
BC Powder Packets are an over-the-counter medication and treatment that are FSA- and HSA-eligible in the U.S., making it easy and affordable to get the relief you need. Each box of BC Powder Original Pain Reliever contains 50 powder packets, ensuring that you always have a supply on hand when you need it.
10. Goodsense Naproxen Sodium Tablets 220 Mg, Pain Reliever And Fever Reducer (Nsaid), 400 Count

GoodSense Naproxen Sodium Tablets 220 mg is a reliable and effective pain reliever and fever reducer that contains naproxen sodium 220 mg, a nonsteroidal anti-inflammatory drug (NSAID). It is comparable to the active ingredient in Aleve Caplets, making it a great alternative with the same quality.
One of the key features of GoodSense Naproxen Sodium Tablets 220 mg is its strength to last up to 12 hours. This long-lasting formula provides pain relief and fever reduction for an entire workday, allowing individuals to power through their daily routine without experiencing discomfort.
This product is designed to temporarily relieve minor aches and pains due to minor pain of arthritis, muscular aches, backache, menstrual cramps, headache, toothache, and the common cold. It also helps to temporarily reduce fever, making it a great solution for individuals who are feeling under the weather.
GoodSense Naproxen Sodium Tablets 220 mg is suitable for adults and children who are 12 years and older. It is a reliable all-day relief option that can help individuals feel comfortable and productive.
The 12-hour pain reliever and fever reducer comes in a capsule-shaped tablet, which is easy to swallow and digest. Additionally, this product is gluten-free, making it a great option for individuals who have dietary restrictions.
Best Toothache Pain Reliever Over Counter FAQs
Are there any natural remedies that can be used as a toothache pain reliever?
Yes, there are several natural remedies that can be used as a toothache pain reliever. One of the most popular remedies is clove oil. Clove oil has natural analgesic properties that can help to numb the pain. Simply apply a small amount of clove oil to a cotton ball and place it directly on the affected tooth. Another remedy is saltwater rinse. Saltwater can help to reduce inflammation and kill bacteria in the mouth. Mix 1/2 teaspoon of salt with 8 ounces of warm water and swish it around in your mouth for 30 seconds before spitting it out. Additionally, applying a cold compress to the affected area can help to reduce swelling and numb the pain. Finally, chewing on garlic or placing a garlic clove on the affected tooth can help to relieve pain due to its natural antibacterial properties. However, it is important to note that these remedies are only temporary and it is still important to see a dentist for proper treatment.
Are there any side effects associated with using over-the-counter toothache pain relievers?
Yes, there can be side effects associated with using over-the-counter toothache pain relievers. Common side effects include upset stomach, nausea, and vomiting. In some cases, these medications can also cause dizziness, drowsiness, and headache. It is important to follow the recommended dosage and not exceed the maximum amount stated on the packaging. Overuse or misuse of these medications can lead to more serious side effects such as liver damage, kidney problems, and bleeding disorders. Additionally, it is important to read the labels carefully to ensure that you are not allergic to any of the ingredients. If you experience any unusual symptoms or side effects, stop taking the medication and consult a healthcare professional. It is also important to note that over-the-counter pain relievers are only a temporary solution and should not be used as a long-term solution for tooth pain. If you are experiencing persistent tooth pain, it is recommended to seek dental care from a professional.
Can over-the-counter pain relievers be used for severe toothaches?
Over-the-counter pain relievers can be used to alleviate mild to moderate toothaches. However, for severe toothaches, it is important to consult with a dentist as soon as possible. Toothaches can be caused by various underlying dental conditions such as tooth decay, abscess, or fractured tooth. These conditions require professional dental treatment to address the underlying cause of the pain. Pain relievers may provide temporary relief, but they do not address the underlying cause of the problem. In addition, taking too many pain relievers can have adverse effects on the body, including liver damage, stomach ulcers, and kidney problems. Therefore, it is important to seek professional dental care for severe toothaches to avoid further complications and resolve the issue once and for all.
Can over-the-counter toothache pain relievers be used alongside other medications?
Over-the-counter toothache pain relievers like ibuprofen or acetaminophen are generally safe to use alongside other medications. However, it is always advisable to consult a healthcare professional before taking any new medication, especially if you are already taking other medication.
Some medications, such as blood thinners, may interact with over-the-counter pain relievers and increase the risk of bleeding. In addition, certain medical conditions, such as liver or kidney disease, may limit the use of some pain relievers.
It is important to follow the recommended dosage and not exceed the maximum daily limit of the medication. Overuse of pain relievers can lead to serious health problems such as liver damage, stomach ulcers, and kidney problems.
If you are unsure about whether you can take over-the-counter pain relievers alongside other medications, it is best to consult a doctor or pharmacist for advice. They can provide guidance on which pain relievers are safe for you to take and in what amounts.
How effective are over-the-counter pain relievers for toothaches?
Over-the-counter pain relievers can be effective in managing toothaches, but their effectiveness can vary depending on the severity of the pain. Most toothaches are caused by inflammation or irritation of the tooth's pulp or nerve, which can produce intense pain that can be difficult to manage. Over-the-counter pain relievers such as ibuprofen and acetaminophen can help to reduce inflammation and alleviate pain. However, these medications may not be enough to provide complete relief for severe toothaches, especially if there is an underlying dental issue that needs to be addressed. In such cases, it's essential to seek professional dental care to diagnose and treat the underlying problem causing the toothache. Over-the-counter pain relievers can provide temporary relief until you can get to a dentist, but they should not be relied on as a long-term solution. If you experience persistent or severe tooth pain, it's important to consult with a dental professional for proper evaluation and treatment.
How long does it take for over-the-counter toothache pain relievers to work?
Over-the-counter (OTC) toothache pain relievers can be an effective way to manage tooth pain until you can see a dentist. The time it takes for these medications to work can vary depending on the severity of the pain and the type of medication you're using. Generally, OTC pain relievers like ibuprofen and acetaminophen can take 30 minutes to an hour to start working and can provide relief for up to six hours. Topical medications like numbing gels can work even faster, providing immediate relief to the affected area. It's important to follow the instructions on the medication packaging and not exceed the recommended dosage. If your tooth pain persists or worsens after taking OTC pain relievers, it's important to schedule an appointment with your dentist as soon as possible.
Is it safe to take over-the-counter toothache pain relievers for an extended period?
Over-the-counter toothache pain relievers are generally safe for short-term use, as long as they are taken according to the instructions on the label. However, if you are taking them for an extended period, it is important to speak with your dentist or doctor to make sure that it is safe for you to continue taking them. Overuse of pain relievers can lead to various side effects, including stomach ulcers, liver damage, and kidney problems. Additionally, taking pain relievers for an extended period may mask an underlying dental problem, which could lead to more serious issues later on. It is always best to consult with a healthcare professional before taking any medication for an extended period, especially if you have any underlying medical conditions or are taking other medications.
What are some of the most popular over-the-counter toothache pain relievers?
Toothache pain can be excruciating, and over-the-counter pain relievers can provide temporary relief until you can see your dentist. Some of the most popular over-the-counter toothache pain relievers include acetaminophen, ibuprofen, and aspirin. Acetaminophen is a pain reliever that can help ease toothache pain for a short period. Ibuprofen, on the other hand, is an anti-inflammatory medication that can help reduce swelling and inflammation that can cause toothache pain. Aspirin is another common pain reliever that can help alleviate toothache pain. However, it is important to note that aspirin should not be placed directly on the affected tooth or gum as it can cause burning and irritation. Instead, it should be taken orally as directed. It is always best to consult with your dentist or healthcare provider to determine the best over-the-counter pain reliever for your specific needs.
What are the recommended dosages for over-the-counter toothache pain relievers?
Over-the-counter toothache pain relievers are generally safe and effective when used as directed. The recommended dosages may vary depending on the active ingredient in the pain reliever.
For acetaminophen, the recommended dosage is usually 500-1000 mg every 4-6 hours as needed, not to exceed 4000 mg in 24 hours. For ibuprofen, the recommended dosage is usually 200-400 mg every 4-6 hours as needed, not to exceed 1200 mg in 24 hours.
It is important to read and follow the label directions carefully, as well as consult with a healthcare professional if you have any questions or concerns about the appropriate dosage for your specific situation. It is also important to not exceed the recommended dosage, as overuse can lead to adverse effects, such as liver damage or gastrointestinal bleeding. If pain persists or worsens after taking the recommended dosage, seek medical attention.
What is the best toothache pain reliever available over the counter?
There are a few over-the-counter pain relievers that can help ease toothache pain. The most commonly recommended pain relievers for toothache include acetaminophen, ibuprofen, and aspirin. Acetaminophen is often recommended as the first line of defense for toothache pain relief, as it is effective in reducing pain and has fewer side effects compared to other pain relievers. Ibuprofen is another effective pain reliever that can help alleviate toothache pain. However, it is important to note that aspirin should not be given to children under the age of 16 due to the risk of Reye's syndrome. Ultimately, the best toothache pain reliever will depend on individual circumstances and should be discussed with a healthcare provider. It is also important to remember that while pain relievers can help manage toothache pain, it is still important to seek dental treatment to address the underlying cause of the pain.