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20 Best Skin Serum For Acne (2023 Updated)

Skin serum for acne is a type of product that can help to improve the appearance of acne and prevent new breakouts from forming. Acne serums typically contain active ingredients that help to unclog pores, control oil production, and reduce inflammation.

These products can be used as part of a daily skin care routine to help keep acne under control.

20 Best Skin Serum For Acne

Product Image Product Name Features Price

Mario Badescu Anti Acne Serum – 1 oz

  • A firming & rejuvenating neck treatment.
  • Contains an innovative blend of hydroxy acids, potent antioxidants, vitamins & natural botanicals.

It Cosmetics Bye Bye Breakout Salicylic Acid Acne Serum

  • Salicylic Acid 2%: Helps target the appearance of active acne breakouts.
  • Lactic Acid 3%: Helps gently exfoliate for smoother-looking skin.

Clinique Acne Solutions Acne Line Correcting Serum – 1.0 oz bottle

  • Potent anti-aging technology help reduces the visibility of fine lines and wrinkles
  • The serum form glides smoothly for an easy and even application

Neutrogena Daily Serum, Stubborn Blackheads – 1.0 fl oz

  • Scent: Unscented
  • Product Warning: Keep out of reach of children
  • Product Form: Serum

Facetheory Porebright Serum S4 | Brightening Face Serum | Hydrating Serum for Face | Niacinamide | Azelaic Acid | Salicylic Acid | 10% Niacinamide

  • Formulated with 10% niacinamide to target enlarged pores
  • Tackles uneven skin tone, pigmentation, redness, and facial photoageing

Versed Just Breathe Clarifying Serum for Oily Skin and Acne-Prone Skin, 1 fl oz

  • This Clarifying Serum helps treat and prevent breakouts while controlling oil and unclogging pores.
  • Use to quiet inflammation and redness while boosting overall clarity—no irritation here.

Juice Beauty Blemish Clearing Serum – 2 fl oz bottle

  • The paraben-free composition makes it an appropriate choice for everyday use
  • Enriched with green tea and organic aloe to help keep your skin hydrated

Derma E Acne Blemish Control Treatment Serum – 2 fl oz

  • The advanced formula helps exfoliate blemishes and blackheads for a healthy-looking skin
  • This tea tree oil infused serum aids to reduce the visibility of pores for a clean skin texture

Cocokind Acne Serum, Probiotic – 1 fl oz

  • Scent: Unscented
  • Product Form: Liquid
  • Sustainability Claims: Cruelty-Free, Recyclable

Minimalist 2% Salicylic Acid Serum for Acne, Blackheads & Open Pores | Reduces Excess Oil & Bumpy Texture | BHA Based Exfoliant for Acne Prone or

  • Glowy Makeup Serum 30ml
  • The hypoallergenic Cica Sleeping Mask is an overnight that helps to soothe stressed skin and strengthen

Organic Acne Treatment & Clear Skin Serum for Acne Prone Skin – Clears Acne & He

  • EFFECTIVE NATURAL ACNE SPOT TREATMENT – Reduces greasiness of skin, stops skin irritation, and heals skin for improved skin appearance.

SkinCeuticals Blemish + Age Defense (1 oz)

  • 1 oz

Fixderma Cosmetic Laboratories Alpha-Beta Acne Gel A Pore Refining Facial Serum for Acne, Oily Skin, 1.05 fl oz, White

  • EXFOLIATES & UNCLOG PORES: A combination of AHA & BHA to offer synergistic effect, exfoliate dead skin cells and unclogs pores

Revolution Skincare 2% Salicylic Acid Serum Super Sized 60ml

  • 60 ml (2.03fl Oz)

Oxy Total Care Acne Treatment, Vitamin C Serum – 1 fl oz

  • Brightens: helps reduce the appearance of blemishes, acne marks and discoloration; makes skin look brighter & smoother
  • Soothes: oil-free, gentle, and designed for all skin types – with a fresh scent

Mario Badescu Anti Acne Serum – 29ml

  • Active ingredients: salicylic acid
  • Complexion type: combination, oily, problematic
  • Effects: Anti-acne, Hydration, Pore-minimising, Regulation of excessive sebum

SkinCeuticals Blemish Age Defense Serum – 30 ml dropper

  • Enriched with salicylic and glycolic acids to diminish fine lines and rejuvenate your skin
  • This paraben-free serum is safe to apply on your skin

Minimalist 10% Niacinamide Face Serum for Acne Marks, Blemishes & Oil Balancing with Zinc | Skin Clarifying Anti Acne Serum for Oily & Acne Prone

  • Minimalist Niacinamide 10% Face Serum
  • Brand: Minimalist
  • Scent: Fragrance-Free

Cosmedix Clarity Skin-Clarifying Serum 1fl oz

  • 30 ml
Mario Badescu Anti Acne Serum – 1 oz
  • A firming & rejuvenating neck treatment.
  • Contains an innovative blend of hydroxy acids, potent antioxidants, vitamins & natural botanicals.
It Cosmetics Bye Bye Breakout Salicylic Acid Acne Serum
  • Salicylic Acid 2%: Helps target the appearance of active acne breakouts.
  • Lactic Acid 3%: Helps gently exfoliate for smoother-looking skin.
Clinique Acne Solutions Acne Line Correcting Serum – 1.0 oz bottle
  • Potent anti-aging technology help reduces the visibility of fine lines and wrinkles
  • The serum form glides smoothly for an easy and even application
Neutrogena Daily Serum, Stubborn Blackheads – 1.0 fl oz
  • Scent: Unscented
  • Product Warning: Keep out of reach of children
  • Product Form: Serum
Facetheory Porebright Serum S4 | Brightening Face Serum | Hydrating Serum for Face | Niacinamide | Azelaic Acid | Salicylic Acid | 10% Niacinamide
  • Formulated with 10% niacinamide to target enlarged pores
  • Tackles uneven skin tone, pigmentation, redness, and facial photoageing
Versed Just Breathe Clarifying Serum for Oily Skin and Acne-Prone Skin, 1 fl oz
  • This Clarifying Serum helps treat and prevent breakouts while controlling oil and unclogging pores.
  • Use to quiet inflammation and redness while boosting overall clarity—no irritation here.
Juice Beauty Blemish Clearing Serum – 2 fl oz bottle
  • The paraben-free composition makes it an appropriate choice for everyday use
  • Enriched with green tea and organic aloe to help keep your skin hydrated
Derma E Acne Blemish Control Treatment Serum – 2 fl oz
  • The advanced formula helps exfoliate blemishes and blackheads for a healthy-looking skin
  • This tea tree oil infused serum aids to reduce the visibility of pores for a clean skin texture
Cocokind Acne Serum, Probiotic – 1 fl oz
  • Scent: Unscented
  • Product Form: Liquid
  • Sustainability Claims: Cruelty-Free, Recyclable
Minimalist 2% Salicylic Acid Serum for Acne, Blackheads & Open Pores | Reduces Excess Oil & Bumpy Texture | BHA Based Exfoliant for Acne Prone or
  • Glowy Makeup Serum 30ml
  • The hypoallergenic Cica Sleeping Mask is an overnight that helps to soothe stressed skin and strengthen
Organic Acne Treatment & Clear Skin Serum for Acne Prone Skin – Clears Acne & He
  • EFFECTIVE NATURAL ACNE SPOT TREATMENT – Reduces greasiness of skin, stops skin irritation, and heals skin for improved skin appearance.
SkinCeuticals Blemish + Age Defense (1 oz)
  • 1 oz
Fixderma Cosmetic Laboratories Alpha-Beta Acne Gel A Pore Refining Facial Serum for Acne, Oily Skin, 1.05 fl oz, White
  • EXFOLIATES & UNCLOG PORES: A combination of AHA & BHA to offer synergistic effect, exfoliate dead skin cells and unclogs pores
Revolution Skincare 2% Salicylic Acid Serum Super Sized 60ml
  • 60 ml (2.03fl Oz)
Oxy Total Care Acne Treatment, Vitamin C Serum – 1 fl oz
  • Brightens: helps reduce the appearance of blemishes, acne marks and discoloration; makes skin look brighter & smoother
  • Soothes: oil-free, gentle, and designed for all skin types – with a fresh scent
Mario Badescu Anti Acne Serum – 29ml
  • Active ingredients: salicylic acid
  • Complexion type: combination, oily, problematic
  • Effects: Anti-acne, Hydration, Pore-minimising, Regulation of excessive sebum
SkinCeuticals Blemish Age Defense Serum – 30 ml dropper
  • Enriched with salicylic and glycolic acids to diminish fine lines and rejuvenate your skin
  • This paraben-free serum is safe to apply on your skin
Minimalist 10% Niacinamide Face Serum for Acne Marks, Blemishes & Oil Balancing with Zinc | Skin Clarifying Anti Acne Serum for Oily & Acne Prone
  • Minimalist Niacinamide 10% Face Serum
  • Brand: Minimalist
  • Scent: Fragrance-Free
Cosmedix Clarity Skin-Clarifying Serum 1fl oz
  • 30 ml

1. Mario Badescu Anti Acne Serum – 1 oz

Mario Badescu Anti Acne Serum - 1 oz

  • A firming & rejuvenating neck treatment.
  • Contains an innovative blend of hydroxy acids, potent antioxidants, vitamins & natural botanicals.
  • Helps firm, hydrate & streamline the delicate skin of neck & jawline.
  • Optimizes skin tone & texture.
  • Reduces the appearance of fine lines & wrinkles.

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Product Details

Specifications

Details
Derived Nutrition Claim Soy Free
Derived Nutrition Claim Nitrite Free
Derived Nutrition Claim Dairy Free
Derived Nutrition Claim Nitrate Free
Derived Nutrition Claim Caffeine Free

2. It Cosmetics Bye Bye Breakout Salicylic Acid Acne Serum

It Cosmetics Bye Bye Breakout Salicylic Acid Acne Serum

  • Salicylic Acid 2%: Helps target the appearance of active acne breakouts.
  • Lactic Acid 3%: Helps gently exfoliate for smoother-looking skin.
  • Postbiotic Ferment: Helps support calm-, balanced-feeling skin.

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IT Cosmetics

Product Details

Specifications

Details
Rich Active Ingredients Salicylic acid ….. Acne treatment
Active Ingredients Salicylic acid ….. Acne treatment
Derived Nutrition Claim Salt Free
Derived Nutrition Claim Soy Free
Derived Nutrition Claim Paraben Free

3. Clinique Acne Solutions Acne Line Correcting Serum – 1.0 oz bottle

Clinique Acne Solutions Acne Line Correcting Serum - 1.0 oz bottle

  • Potent anti-aging technology help reduces the visibility of fine lines and wrinkles
  • The serum form glides smoothly for an easy and even application
  • Diligently formed to help restore skin elasticity for a healthy looking skin

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Clinique
Ulta Beauty

Product Details

Specifications

Details
Oil-Free Yes
Product Form Serum
Technology Potent
Container Type Bottle
Oil-Free 1.0 oz

Reviews From Real Customers

Beach Hippy
SuzySue
Tina17

4. Neutrogena Daily Serum, Stubborn Blackheads – 1.0 fl oz

Neutrogena Daily Serum, Stubborn Blackheads - 1.0 fl oz

  • Scent: Unscented
  • Product Warning: Keep out of reach of children
  • Product Form: Serum
  • Beauty Purpose: Anti-Acne, Pore Cleansing
  • Recommended Skin Type: Normal, Acne-Prone, Combination

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Target

Product Details

Specifications

Details
Rich Active Ingredients Salicylic Acid 0.5% ….. Acne treatment
Active Ingredients Salicylic Acid 0.5% ….. Acne treatment
Derived Nutrition Claim Salt Free
Derived Nutrition Claim Soy Free
Derived Nutrition Claim Paraben Free

5. Facetheory Porebright Serum S4 | Brightening Face Serum | Hydrating Serum for Face | Niacinamide | Azelaic Acid | Salicylic Acid | 10% Niacinamide

Facetheory Porebright Serum S4 | Brightening Face Serum | Hydrating Serum for Face | Niacinamide | Azelaic Acid | Salicylic Acid | 10% Niacinamide

  • Formulated with 10% niacinamide to target enlarged pores
  • Tackles uneven skin tone, pigmentation, redness, and facial photoageing
  • Azelaic acid, derived from wheat, rye and barley, combats clogged pores and acne
  • Salicylic acid gently exfoliates
  • Most skin types, including oily, combination, sensitive and mature skin

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facetheory.com

Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Product Dimensions 1.38 x 1.38 x 4.13 inches; 3.21 Ounces
Country of Origin United Kingdom

Reviews From Real Customers

Asna
Sofia
S

6. Versed Just Breathe Clarifying Serum for Oily Skin and Acne-Prone Skin, 1 fl oz

Versed Just Breathe Clarifying Serum for Oily Skin and Acne-Prone Skin, 1 fl oz

  • This Clarifying Serum helps treat and prevent breakouts while controlling oil and unclogging pores.
  • Use to quiet inflammation and redness while boosting overall clarity—no irritation here.
  • Willow bark extract, niacinamide, and a zinc blend work together to keep acne and oil at bay.
  • High-performance skincare with purpose.

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Specifications

Details
Is Discontinued By Manufacturer No
Product Dimensions 1.7 x 1.75 x 4 inches; 1.92 Ounces
Country of Origin Thailand

7. Juice Beauty Blemish Clearing Serum – 2 fl oz bottle

Juice Beauty Blemish Clearing Serum - 2 fl oz bottle

  • The paraben-free composition makes it an appropriate choice for everyday use
  • Enriched with green tea and organic aloe to help keep your skin hydrated
  • This serum glides smoothly on your skin for an even application

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Product Details

Specifications

Details
Product Form Serum
Container Type Bottle
Volume 2 fl oz
Paraben-Free Yes
Cruelty-Free Yes

Reviews From Real Customers

brittany.h
happyATL
Desi

8. Derma E Acne Blemish Control Treatment Serum – 2 fl oz

Derma E Acne Blemish Control Treatment Serum - 2 fl oz

  • The advanced formula helps exfoliate blemishes and blackheads for a healthy-looking skin
  • This tea tree oil infused serum aids to reduce the visibility of pores for a clean skin texture
  • Blend of lavender and chamomile assists to deliver a soothing appeal to your skin

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Specifications

Details
Weight 2 fl oz
Product Form Serum
Anti-Acne Yes
Vegan Yes
Cruelty-Free Yes

9. Cocokind Acne Serum, Probiotic – 1 fl oz

Cocokind Acne Serum, Probiotic - 1 fl oz

  • Scent: Unscented
  • Product Form: Liquid
  • Sustainability Claims: Cruelty-Free, Recyclable
  • Beauty Purpose: Smoothing, Hydrating, Anti-Acne
  • Recommended Skin Type: Combination, Mature, Oily, Dry, Normal, Acne-Prone, Sensitive

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Amazon
Ulta Beauty
cocokind
Target

Product Details

Specifications

Details
Rich Active Ingredients Salicylic acid 1.5% ….. Acne treatment
Active Ingredients Salicylic acid 1.5% ….. Acne treatment
Derived Nutrition Claim Salt Free
Derived Nutrition Claim Paraben Free
Derived Nutrition Claim Nitrite Free

10. Minimalist 2% Salicylic Acid Serum for Acne, Blackheads & Open Pores | Reduces Excess Oil & Bumpy Texture | BHA Based Exfoliant for Acne Prone or

Minimalist 2% Salicylic Acid Serum for Acne, Blackheads & Open Pores | Reduces Excess Oil & Bumpy Texture | BHA Based Exfoliant for Acne Prone or

  • Glowy Makeup Serum 30ml
  • The hypoallergenic Cica Sleeping Mask is an overnight that helps to soothe stressed skin and strengthen
  • Tiger grass Strongly for sensitive and dry skin

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eBay – faibi-india
Walmart – Uprisng Science Private Limited

Product Details

Reviews From Real Customers

Saijel
Longkumer
V.J.

11. Organic Acne Treatment & Clear Skin Serum for Acne Prone Skin – Clears Acne & He

Organic Acne Treatment & Clear Skin Serum for Acne Prone Skin - Clears Acne & He

  • EFFECTIVE NATURAL ACNE SPOT TREATMENT – Reduces greasiness of skin, stops skin irritation, and heals skin for improved skin appearance.
  • REDUCE THE SIZE OF PORES – Botanical polyphenol rich ingredients acts as an exfoliant, allowing your pores to go back down to their original size.
  • Brand: Simply Radiant Beauty.
  • Color: Ace Prone Skin.

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Glimmer Goddess Organic Skin Care

Product Details

Specifications

Details
Product Dimensions 4.7 x 1.3 x 0.8 inches

Reviews From Real Customers

Felicity J.
Danyel S.
Patrice S.

12. ANAIRUI Best Acne Treatment Serum for Acne Prone Skin Pimple Smoothing 30ml 1fl oz

ANAIRUI Best Acne Treatment Serum for Acne Prone Skin Pimple Smoothing 30ml 1fl oz

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ANAiRUi

Product Details

Reviews From Real Customers

Marteel
Halsey N.

13. SkinCeuticals Blemish + Age Defense (1 oz)

SkinCeuticals Blemish + Age Defense (1 oz)

  • 1 oz

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SkinCeuticals
Bluemercury

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Details
Weight 1 oz

Reviews From Real Customers

CD87
V

14. Fixderma Cosmetic Laboratories Alpha-Beta Acne Gel A Pore Refining Facial Serum for Acne, Oily Skin, 1.05 fl oz, White

Fixderma Cosmetic Laboratories Alpha-Beta Acne Gel A Pore Refining Facial Serum for Acne, Oily Skin, 1.05 fl oz, White

  • EXFOLIATES & UNCLOG PORES: A combination of AHA & BHA to offer synergistic effect, exfoliate dead skin cells and unclogs pores
  • HEALING & EVEN SKIN TONE: Heals blemishes and prevents new ones from forming, regulates skin tone
  • OIL REGULATOR: Balances oil (sebum) production, neutralizes free radicals
  • KEY INGREDIENTS: Glycolic acid, Salicylic acid, Retistar, Multifruit BSC, Tea tree oil

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gallerialine.com

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Specifications

Details
Product Dimensions 5.16 x 2.95 x 1.61 inches

Reviews From Real Customers

Sagarika
Bibhuti
Karampreet

15. Revolution Skincare 2% Salicylic Acid Serum Super Sized 60ml

Revolution Skincare 2% Salicylic Acid Serum Super Sized 60ml

  • 60 ml (2.03fl Oz)

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BEAUTY BAY
Revolution Beauty

Product Details

Specifications

Details
Texture serum
Skin issues blemishes, breakouts, excess sebum
Time of application morning and/or evening
Skin type combination to oily skin, blemish-prone skin

Reviews From Real Customers

Dmitry P
Jade

16. Oxy Total Care Acne Treatment, Vitamin C Serum – 1 fl oz

Oxy Total Care Acne Treatment, Vitamin C Serum - 1 fl oz

  • Brightens: helps reduce the appearance of blemishes, acne marks and discoloration; makes skin look brighter & smoother
  • Soothes: oil-free, gentle, and designed for all skin types – with a fresh scent

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oxyskincare.com

Product Details

Specifications

Details
Units in Package 1
Unit Size 1 fl oz
Indications Uses: For the treatment of acne. Helps prevent new acne blemishes.
Directions General directions: Clean the skin thoroughly before applying this product. Use one to three drops to cover the entire affected area with a thin layer one to three times daily. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day Sensitivity Test for a New User. Apply product sparingly to one or two small affected areas during the first 3 days If no discomfort occurs, follow the directions stated above.
Ingredients Active Ingredients: Salicylic Acid (0.5 %). Purpose: Acne Treatment. Inactive Ingredients: Ethoxydiglycol, Water, Butylene Glycol, Glycerin, Disteareth-100 IPDI, 3-0-Ethyl Ascorbic Acid, PEG-8 Dimethicone, PEG-8 Ricinoleate, Bis-PEG-15 Dimethicone/IPDI Copolymer, Fragrance, Ganoderma Lucidum (Mushroom) Stem Extract, Hyaluronic Acid, Potassium Sorbate, Propanediol, Silanetriol, Sodium Benzoate, Xanthan Gum

Reviews From Real Customers

Sonya A.
holly.j
Chey K.

17. Mario Badescu Anti Acne Serum – 29ml

Mario Badescu Anti Acne Serum - 29ml

  • Active ingredients: salicylic acid
  • Complexion type: combination, oily, problematic
  • Effects: Anti-acne, Hydration, Pore-minimising, Regulation of excessive sebum
  • When to use: night

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Loja Glamourosa
REVOLVE
Feelunique ROW

Product Details

Specifications

Details
Texture gel
Skin issues dehydration, excess sebum, blemishes, congestion
Skin type combination, oily and acne-prone skins

Reviews From Real Customers

shathiii.k
amy.s
hurumi

18. SkinCeuticals Blemish Age Defense Serum – 30 ml dropper

SkinCeuticals Blemish Age Defense Serum - 30 ml dropper

  • Enriched with salicylic and glycolic acids to diminish fine lines and rejuvenate your skin
  • This paraben-free serum is safe to apply on your skin
  • Serum form offers easy and even application

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Care Lineage

Product Details

Specifications

Details
Product Form Serum
Suitable Skin Types Oily, combination
Paraben-Free Yes
Oil-Free Yes
Volume 30 ml

19. Minimalist 10% Niacinamide Face Serum for Acne Marks, Blemishes & Oil Balancing with Zinc | Skin Clarifying Anti Acne Serum for Oily & Acne Prone

Minimalist 10% Niacinamide Face Serum for Acne Marks, Blemishes & Oil Balancing with Zinc | Skin Clarifying Anti Acne Serum for Oily & Acne Prone

  • Minimalist Niacinamide 10% Face Serum
  • Brand: Minimalist
  • Scent: Fragrance-Free
  • Skin Type: All
  • Item Form: Serum

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Distacart

Product Details

Specifications

Details
Scent Fragrance-Free
Skin Type All
Item Form Serum
Skin Tone All Skin Tone
Use for Face

Reviews From Real Customers

Aaditi
Yashpreet K.

20. Cosmedix Clarity Skin-Clarifying Serum 1fl oz

Cosmedix Clarity Skin-Clarifying Serum 1fl oz

  • 30 ml

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Dermstore.com
Cosmedix-Shop

Product Details

Specifications

Details
Product Net Content UOM Fluid Ounces
Contained Battery Type 1
Makeup Form Night Care
Piece Count 1
Count Per Pack 1

Reviews From Real Customers

Vivi
amber.l
Veronika L.

Conclusion

The bottom line is that this skin serum for acne is an effective way to get rid of acne. It is affordable, easy to use, and has a wide variety of benefits. If you are looking for an acne treatment, this is definitely one to consider.

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