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Best Probiotics For C Diff (2025 Update)

If you’re looking for ways to manage C diff symptoms, probiotics may be a promising solution. Probiotics are live microorganisms that are beneficial to your gut’s health. C diff patients can experience a range of symptoms, including frequent diarrhea, abdominal pain, and cramping. A high-quality probiotic can help reduce these symptoms and improve overall gut health.

Before buying probiotics for C diff, there are a few factors that you need to consider. First, look for a probiotic supplement with a diverse set of bacterial strains. This will ensure that your gut's microbiome is well-balanced and healthy. Second, check the potency and dosing of the probiotic. An effective probiotic should deliver at least 50 billion CFUs (colony-forming units) to your gut. Finally, make sure that the probiotic is safe and free from harmful additives or allergens.

Do you struggle with C diff symptoms such as diarrhea, cramping, and bloating? Are you looking for a safe and natural solution to alleviate these symptoms? If so, probiotics may be a worthwhile option for you to explore. With the right probiotic supplement, you can improve your gut health, reduce inflammation, and boost your immune system. But with so many probiotic brands and options available, how do you know which one is the best for your needs? In this article, we’ll help you navigate the world of probiotics for C diff so that you can choose the right product with confidence.

10 Best Probiotics For C Diff

# Product Image Product Name Product Notes Check Price
1
It is an ideal daily probiotic supplement that supports digestive health and comes in a twin pack of 200 tablets.
2
This product is ideal for promoting digestive health and supporting a healthy immune system.
3
This product is ideal for improving digestive health and is recommended by doctors and gastroenterologists.
4
This probiotic and prebiotic supplement is ideal for enhancing intestinal tract support and protection.
5
It is ideal for enhancing immune function in the gut through probiotics contained in 60 capsules.
6
It is an ideal dietary supplement for supporting digestive health, free of soy, gluten, and non-GMO.
7
Ideal for promoting digestive balance and supporting overall gut health with 15 billion CFU and 13 strains of probiotics.
8
This product is ideal as a probiotic supplement for both men and women, containing 10 billion CFU per serving.
9
This product is ideal for improving gut health, digestion, and supporting candida cleanse while strengthening the immune system.
10
This product is ideal for promoting digestive and immune health by flushing out bad bacteria and boosting good bacteria.
It is an ideal daily probiotic supplement that supports digestive health and comes in a twin pack of 200 tablets.
This product is ideal for promoting digestive health and supporting a healthy immune system.
This product is ideal for improving digestive health and is recommended by doctors and gastroenterologists.
This probiotic and prebiotic supplement is ideal for enhancing intestinal tract support and protection.
It is ideal for enhancing immune function in the gut through probiotics contained in 60 capsules.
It is an ideal dietary supplement for supporting digestive health, free of soy, gluten, and non-GMO.
Ideal for promoting digestive balance and supporting overall gut health with 15 billion CFU and 13 strains of probiotics.
This product is ideal as a probiotic supplement for both men and women, containing 10 billion CFU per serving.
This product is ideal for improving gut health, digestion, and supporting candida cleanse while strengthening the immune system.
This product is ideal for promoting digestive and immune health by flushing out bad bacteria and boosting good bacteria.

1. Digestive Twin Pack Probiotic, 200 Tabs

Nature's Bounty Acidophilus Probiotic is a dietary supplement that comes in (2) bottles, each containing 100 tablets. This supplement is specifically designed to provide friendly bacteria for the digestive system. It is a stomach-friendly supplement that does not contain any artificial colors, flavors, or sweeteners. It is important to note that this supplement needs to be refrigerated to ensure its effectiveness.

Nature’s Bounty Probiotic Acidophilus contains over 100 million active Lactobacillus Acidophilus at the time of manufacture, which includes naturally occurring metabolic products produced by Lactobacilli. This makes it a highly potent supplement that can help keep the digestive system healthy and functioning optimally.

Nature's Bounty is a brand that is synonymous with quality, consistency, and scientific research. Each of their products is made using the latest breakthroughs in nutritional science and the finest ingredients, which ensures that they provide supplements of unparalleled quality and value.

It is important to note that every Nature's Bounty product undergoes numerous quality tests throughout the manufacturing process to verify its purity and potency. The ingredients and final product are tested in their microbiological laboratory to make certain that the product is pure and free from any contaminants.

Their supplements are overseen by scientists, manufacturing specialists, and quality experts, all of whom are dedicated to maintaining the highest quality standards. Nature's Bounty only uses ingredients from suppliers that meet GMP supplement quality standards, which ensures that their supplements are of the highest quality.

2. Now Supplements, Saccharomyces Boulardii, 5 Billion Cfu Probiotic, 60 Veg Capsules

The PROBIOTIC 5 BILLION CFU is a dietary supplement that supports a healthy balance of intestinal flora. It contains live bacterial strains that aid in maintaining digestive health, especially when experiencing occasional diarrhea, making it an ideal supplement for travelers.

Customers should be aware that exposure to heat or sunlight may lead to melting or damage of the product. Therefore, it is recommended that customers be available during product delivery to ensure safe receipt of the supplement.

The PROBIOTIC 5 BILLION CFU is certified Soy Free, Non-GMO, Vegan/Vegetarian, Nut Free, Gluten Free, Dairy Free, Egg Free, Keto Friendly, Kosher, and Halal. These certifications ensure that the supplement meets the dietary restrictions of various individuals, making it more accessible to a wider range of users.

The manufacturing process of the PROBIOTIC 5 BILLION CFU is of the highest quality, as evidenced by its NPA A-rated GMP certification. Every aspect of the NOW manufacturing process, including laboratory/testing methods for stability, potency, and product formulation, has been examined to ensure that the supplement is of the highest quality.

The PROBIOTIC 5 BILLION CFU is packaged in the USA by a family-owned and operated company since 1968, providing customers with the assurance that they are supporting a reputable business. During the summer months, the supplement may arrive warm due to shipping, but Amazon stores and ships the product in accordance with the manufacturer's recommendations, ensuring that the supplement remains safe for consumption.

3. Digestive Health Probiotics – Align 63 Capsules

Align Probiotic is a trusted brand that has been recommended by Gastroenterologists for over 15 years. With nearly 2x more recommendations than any other probiotic brand, Align Probiotic is the top choice for those seeking to improve their digestive health.

Developed by Gastroenterologists and backed by over 20 years of research, Align Probiotic contains the unique strain Bifidobacterium 35624TM. This strain is well-studied and has been found to naturally soothe occasional abdominal discomfort, gas, and bloating. It is a natural way to build and support a healthy digestive system.

In a clinical study, 4 out of 5 people reported feeling more confident in their digestive health after using Align Probiotic. With just one capsule a day, this supplement can help support your digestive balance.

Align Probiotics are formulated with guaranteed potency and levels of live probiotic CFUs in each dose. Each lot is DNA tested to ensure it contains the unique Bifidobacterium 35624TM strain. This ensures that you are getting the full benefits of this probiotic supplement.

For those with dietary restrictions, Align Probiotics are gluten-free, vegetarian, and soy-free. Unlike some other probiotics, Align Probiotic does not require refrigeration and is enclosed in advanced packaging to ensure potency and survivability.

4. Intestinal Defense – Probiotic + Prebiotic Supplement

Introducing the Intestinal Tract Support – Saccharomyces Boulardii + MOS, a clinically documented probiotic yeast that provides support to the intestinal tract. This product is a game-changer as it does not require refrigeration and can be conveniently stored in a cool, dry place.

This probiotic + prebiotic supplement contains Saccharomyces Boulardii, a probiotic yeast that has been clinically shown to benefit individuals who are in greater need of intestinal support, such as those who travel. With the inclusion of MOS, a prebiotic that feeds the beneficial bacteria in the gut, this supplement offers a complete solution for maintaining optimal gut health.

At the time of consumption, this supplement delivers a minimum of 5 billion CFUs, ensuring that your gut gets the support it needs to function at its best. This product is rated #1 in customer satisfaction by the ConsumerLab Survey of Supplement Users, making it a highly trusted and reliable source of intestinal tract support.

5. Thorne Sacro-B Probiotic – Enhances Immune Function In The Gut – 60 Capsules

Introducing Thorne Sacro-B Probiotic, a supplement that supports a healthy digestive system by promoting the growth of beneficial gut flora. This unique blend of probiotics is designed to aid in digestion and occasional constipation relief.

Thorne Sacro-B Probiotic also provides immune system support by increasing the secretion of IgA, which strengthens the gut's first line of defense.

What sets Thorne Sacro-B Probiotic apart is its unique blend of probiotics that work together to support gut health, immune function, and digestion.

Thorne is a trusted name in the supplement industry, chosen by elite athletes and over 100 professional teams. As the only supplement manufacturer to collaborate with the prestigious Mayo Clinic on wellness research and content, Thorne is committed to providing high-quality supplements that are backed by science. Additionally, Thorne is proud to be a partner of the U.S. Olympic Teams.

Take control of your gut health with Thorne Sacro-B Probiotic and experience the benefits of a healthy digestive system and a stronger immune system.

6. Probiotic Powerhouse: 70b Cfu Gut Health Support

Dr. Mercola's Complete Probiotics (70 Billion CFU) is a high-quality dietary supplement that comes in a bottle with 90 servings. The product is formulated based on Dr. Mercola's belief in providing the best quality products, and it is free from gluten, GMO, and soy, making it safe for consumption by people with dietary restrictions.

The Complete Probiotics supplement is designed to promote the optimal growth of healthy bacteria in the gut, which can provide support for immune health. This is achieved through the inclusion of 10 different probiotic strains, each carefully selected for its unique health benefits. The product has also demonstrated high potency through independent laboratory tests, ensuring that consumers receive the full benefits of the probiotic strains.

Dr. Mercola stands behind the quality of all their products, including Complete Probiotics, with a full 30-day money-back guarantee. If for any reason a customer is not satisfied with their purchase, they can return it to Dr. Mercola for a full refund.

7. Ultimate Digestive Balance Probiotic – Garden Of Life

Primal Defense 15 billion CFU probiotic supplement is a powerful dietary supplement that provides a multitude of benefits to support digestive health. This supplement contains a blend of Lactobaccilus acidophilus, Bifidobacteria, and other strains to maximize the benefits of a healthy diet, boost nutrient absorption, relieve constipation and support digestive health.

One of the unique features of this probiotic supplement is that it contains Homeostatic Soil Organisms (HSO), making it the only shelf-stable probiotic powder formula with this ingredient. HSO provides a whole food blend that enhances the effectiveness of this supplement, ensuring that your body receives the full range of benefits.

In addition, Primal Defense 15 billion CFU probiotic supplement has 13 hardy beneficial strains for immune system health. These strains work together to provide the necessary support for a healthy immune system.

This supplement also promotes regular, healthy, and comfortable bowel movements, making it an ideal choice for those looking for probiotics for constipation. With its colon health support, Primal Defense ensures that your digestive system is functioning at its best.

Finally, this vegetarian probiotic supplement is whole food, gluten-free, and suitable for vegetarians, making it a balanced and healthy choice for an internal environment.

8. Saccharomyces Probiotic Capsules – 120 Count

Pure TheraPro Rx's Saccharomyces Boulardii Probiotic is a powerful supplement designed to help maintain normal balance in the intestinal flora. This patented and clinically studied strain has a regulatory effect on the intestinal flora, providing maximum benefits to the user.

One of the key factors that sets Pure TheraPro Rx's probiotics apart from others on the market is the absence of fillers, excipients, flow agents, or the additive magnesium stearate. This additive is believed to inhibit nutrient absorption, which can reduce the efficacy of the supplement. The company's commitment to finding authentic versions/forms of nutrients means that users can trust the purity of the supplement.

Another unique feature of the Saccharomyces Boulardii Probiotic is that it does not require refrigeration. The proprietary process used in the manufacturing of this supplement involves less-aggressive drying at a controlled temperature and lower vacuum to preserve complete probiotic yeast cells. This process delays the aging process, ensuring that the supplement remains stable at room temperature for 24 months.

Each Pure TheraPro Rx Saccharomyces probiotic capsule delivers a minimum of 10 billion colony-forming units per daily serving (250mg per capsule). These probiotics supplement capsules quickly achieve high concentrations in the GI tract, then clear within 3-5 days after discontinuing use. Users can take 1 to 2 capsules daily in the morning or as directed by a healthcare provider.

Pure TheraPro Rx was founded in Denver, Colorado, with the mission of formulating and manufacturing the highest quality supplements available on the market today. The company's commitment to purity means that they only use patented, clinically studied ingredients and never utilize fillers, flow agents, excipients, or ingredients sourced from China. Additionally, Pure TheraPro Rx never uses dairy, gluten, corn, soy, or other common allergens in any of their class-leading, practitioner-recommended formulas.

9. Florafix: Gut & Immune Probiotic Supplement

The Latero-Flora supplement is a reliable and effective way to promote intestinal balance and support proper digestion for overall good health. Featuring Brevibacillus laterosporus, this supplement encourages the growth of friendly colonies in the gut to help with occasional bloating, constipation, and gas relief, all while promoting gut health.

Maintaining a healthy immune system is crucial, and the intestinal flora found in Latero-Flora helps you digest food properly, which supports overall wellness. Additionally, this supplement can help restore the occasional upset stomach and support a detox and candida cleanse to strengthen your gut against harmful organisms.

Brevibacillus laterosporus is a naturally occurring, spore-forming organism that's able to survive in stomach acid and colonize the intestinal tract. Free of gluten, soy, dairy, GMOs, nuts, sugar, artificial flavors, synthetic dyes, and toxic fillers, Latero-Flora is the perfect choice for those who are health-conscious and looking for a supplement that's safe and effective.

Unlike most probiotics, Latero-Flora is shelf-stable and does not require refrigeration due to its unique strain. Other probiotics may lack potency and not have the required servings to make a significant impact. It is recommended to pair Latero-Flora with a digestive enzyme supplement to maximize the benefits.

Manufactured in a state-of-the-art cGMP certified facility in Phoenix, Arizona, Latero-Flora is made in the USA with quality and safety in mind. The manufacturer takes pride in their product and offers a 30-day guarantee for all bottles sold.

10. Floraboost: Dual Action Probiotics For Health

Florastor is a dietary supplement that is safe for long-term use and is not associated with any complications. It is designed to transit through the digestive tract and maintain steady-state levels throughout the administration period. However, it is important to note that exposure to heat or sunlight may lead to melting or damage of the product. Therefore, customers are advised to be available during product delivery to prevent any damage.

It is recommended to not mix Florastor in carbonated, very hot liquid, or alcohol-containing beverages or foods. The supplement is viable for only thirty minutes after being added to food or beverages. It is also important to note that the packaging may vary from the image shown.

Florastor can be taken with or without food. However, it is not recommended to take Florastor in conjunction with anti-fungals. Research has shown that less than 1% of patients report constipation or thirst after using Florastor.

For those on restricted diets, Florastor contains 33 mg lactose, which has been proven to increase Lactase production. This helps with the digestion of lactose. Furthermore, Florastor is a gluten-free dietary supplement. However, it is important to note that it may contain traces of soy.

During the summer months, the product may arrive warm due to shipping. However, Amazon stores and ships products in accordance with the manufacturer's recommendations when provided.

Best Probiotics For C Diff FAQs

Are there any dietary or lifestyle changes that can enhance the effectiveness of probiotics for C. diff?

Clostridium difficile infection (CDI) is a bacterial infection that can cause severe diarrhea and inflammation of the colon. Probiotics have been found to be effective in preventing and treating CDI. However, there are certain dietary and lifestyle changes that can enhance the effectiveness of probiotics for C. diff.

Firstly, it is important to consume a diet that is high in fiber and low in processed foods. This can help to promote healthy gut bacteria and provide a favorable environment for probiotics to thrive.

Secondly, reducing stress levels and getting enough sleep can also enhance the effectiveness of probiotics. Stress and lack of sleep can weaken the immune system and disrupt the balance of gut bacteria, making it more difficult for probiotics to colonize the gut.

Lastly, it is important to choose the right probiotic strain for treating CDI. Look for strains that have been clinically proven to be effective for treating C. diff, such as Lactobacillus rhamnosus GG and Saccharomyces boulardii.

In conclusion, incorporating a healthy diet, reducing stress levels, and choosing the right probiotic strain can enhance the effectiveness of probiotics for C. diff. However, it is always important to consult with a healthcare professional before starting any new dietary or lifestyle changes.

Are there any potential side effects or risks associated with taking probiotics for C. diff?

Probiotics are generally considered safe and have been shown to be effective in preventing and treating various health conditions, including C. diff infections. However, it's important to note that taking probiotics may have some potential side effects and risks.

One potential side effect is gastrointestinal discomfort, such as bloating, gas, and diarrhea. This is more likely to occur if you take too many probiotics or if your body is not used to them. In rare cases, probiotics may also cause more serious side effects, such as infections in people with weakened immune systems.

Additionally, it's important to choose the right type of probiotic for C. diff. Some strains of probiotics may not be effective against C. diff, while others may actually worsen the infection. Therefore, it's important to speak with a healthcare provider to determine the best probiotic for your specific needs.

Overall, while probiotics can be a helpful tool in preventing and treating C. diff infections, it's important to be aware of the potential side effects and risks associated with their use.

Are there any specific strains of probiotics that are best for treating C. diff?

Yes, there are specific strains of probiotics that have been found to be effective in treating C. diff. The most commonly studied strains are Lactobacillus acidophilus, Lactobacillus rhamnosus GG, and Saccharomyces boulardii. These strains have been found to reduce the risk of recurrent C. diff infections and improve symptoms.

Lactobacillus acidophilus is a type of bacteria that is naturally found in the human gut and has been shown to inhibit the growth of C. diff. Lactobacillus rhamnosus GG is another strain that has been found to be effective in treating C. diff. It has been shown to reduce the severity of symptoms and shorten the duration of the infection.

Saccharomyces boulardii is a type of yeast that has been found to be effective in preventing recurrent C. diff infections. It works by competing with C. diff for nutrients and preventing it from colonizing the gut.

It is important to note that probiotics should not be used as a substitute for antibiotics in the treatment of C. diff, but rather as an adjunct therapy to support the gut microbiome and reduce the risk of recurrent infections.

Can probiotics be taken alongside antibiotics for C. diff treatment?

Yes, probiotics can be taken alongside antibiotics for C. diff treatment. In fact, some studies suggest that taking probiotics along with antibiotics can help prevent the overgrowth of C. diff bacteria and reduce the risk of recurrent infections. However, it is important to note that not all probiotics are created equal and some strains may be more effective than others. It is recommended to consult with a healthcare professional before taking any probiotic supplement, especially if you are currently taking antibiotics or have a weakened immune system. Additionally, it is important to continue taking the full course of antibiotics as prescribed by your healthcare provider to effectively treat the C. diff infection.

Can probiotics be used as a preventative measure against C. diff infections?

Clostridioides difficile (C. diff) is a type of bacteria that can cause severe diarrhea, inflammation of the colon, and even death. Antibiotics are commonly used to treat C. diff infections, but they can also disrupt the balance of the gut microbiome, making the patient more susceptible to future infections.

Probiotics are live microorganisms that can provide health benefits when consumed in adequate amounts. Some studies suggest that specific strains of probiotics may help prevent C. diff infections by restoring the balance of the gut microbiome. However, the evidence is not conclusive, and more research is needed to determine the most effective strains and dosages of probiotics for preventing C. diff infections.

It is important to note that probiotics should not be used as a replacement for antibiotics in the treatment of C. diff infections. Antibiotics are still the most effective treatment for active infections, and probiotics should only be used as a complementary therapy under the guidance of a healthcare professional.

How do probiotics work to treat C. diff infections?

Probiotics are live microorganisms that are beneficial to human health. They work by restoring the balance of bacteria in the gut, which can be disrupted by antibiotics. Clostridium difficile (C. diff) is a type of bacteria that can cause severe infections, particularly in individuals who have taken antibiotics. Probiotics can help to treat C. diff infections by providing healthy bacteria that can compete with and outcompete the harmful bacteria.

Specifically, probiotics containing strains of Lactobacillus and Bifidobacterium have been shown to be effective in treating C. diff infections. These strains produce lactic acid and other acids which create an environment in the gut that is hostile to C. diff. Additionally, probiotics can help to boost the immune system, which can aid in fighting off the infection.

It is important to note that probiotics should not be used as a sole treatment for C. diff infections. Antibiotics are still the primary treatment, and probiotics should be used as a complementary therapy under the supervision of a healthcare professional.

How long does it typically take for probiotics to show results in treating C. diff?

The effectiveness of probiotics in treating C. diff varies from person to person, and as such, the time it takes for probiotics to show results can also differ. However, some studies have shown that probiotics can start to show positive effects within a few days to a week of starting the treatment.

It's important to note that probiotics should not be used as the sole treatment for C. diff. Antibiotics are usually prescribed to kill the C. diff bacteria, and probiotics are recommended as a supplement to help restore the balance of healthy bacteria in the gut.

Additionally, the type of probiotic used can also affect the time it takes to see results. Some strains of probiotics have been shown to be more effective than others in treating C. diff. Therefore, it's important to choose a probiotic that contains the most effective strains for treating C. diff and to follow the recommended dosage and treatment duration.

Overall, probiotics can be a helpful addition to the treatment of C. diff, but it's important to consult with a healthcare professional for a proper diagnosis and treatment plan.

What are the most effective probiotics for treating C. diff?

Clostridium difficile, commonly known as C. diff, is a bacterium that causes diarrhea and colitis. Probiotics have been suggested as a potential treatment for C. diff, but the most effective strains are still being researched.

One of the most studied probiotics for C. diff is a strain of bacteria called Saccharomyces boulardii. This probiotic has shown promise in reducing the severity and duration of C. diff infections, as well as preventing recurrent infections.

Another probiotic that has shown potential in treating C. diff is Lactobacillus rhamnosus. This strain has been found to inhibit the growth of C. diff and may be effective in preventing recurrent infections.

Other probiotics that have been studied for their potential benefits in treating C. diff include Bifidobacterium bifidum, Lactobacillus acidophilus, and Streptococcus thermophilus. However, more research is needed to determine their effectiveness.

It is important to note that while probiotics may be a helpful adjunct treatment for C. diff, they should not be used as a replacement for antibiotics or other medical interventions recommended by a healthcare professional.

What is the recommended dosage of probiotics for treating C. diff?

C. diff or Clostridioides difficile infection is a type of bacterial infection that affects the gut and causes diarrhea. Probiotics are live microorganisms that can help restore the natural balance of bacteria in the gut and alleviate the symptoms of C. diff. However, the recommended dosage of probiotics for treating C. diff can vary depending on the severity of the infection and individual needs.

According to some studies, a high dose of probiotics, typically between 10-20 billion colony-forming units (CFUs) per day, may be beneficial for treating C. diff. However, it's important to note that probiotics should not be used as a replacement for antibiotics in treating C. diff. Antibiotics are still the primary treatment for this condition, and probiotics should only be used as a complementary therapy.

It's also advisable to consult with a healthcare professional before taking probiotics for C. diff. They can recommend the appropriate dosage and strain of probiotics that can best suit your individual needs and help you achieve the desired results.

What should I look for when choosing a probiotic supplement for C. diff treatment?

When choosing a probiotic supplement for C. diff treatment, there are several factors to consider. Firstly, you should look for a supplement that contains the specific strains of probiotics that have been clinically proven to be effective in treating C. diff, such as Lactobacillus rhamnosus GG and Saccharomyces boulardii. Additionally, it's important to choose a supplement that has a high number of colony-forming units (CFUs), as this will ensure that you're getting a therapeutic dose of probiotics.

Another important consideration when choosing a probiotic supplement for C. diff treatment is the form of the supplement. Capsules and tablets are the most common forms, but you may also find probiotic powders, liquids, and chewables. Choose the form that is most convenient for you and that you are most comfortable taking.

Finally, you should look for a probiotic supplement that is manufactured by a reputable company and that has been independently tested for purity and potency. This will help to ensure that you're getting a high-quality product that is safe and effective for treating C. diff.