If you’re looking for some relief from the pain and discomfort of arthritis, you may be considering over-the-counter medications. With so many options out there, it can be difficult to determine which ones are the best fit for your needs. Before making a decision, it’s important to consider several factors, such as your medical history, any other medications you may be taking, and the severity of your symptoms.
When looking for the best OTC meds for arthritis, it’s crucial to read labels carefully and consult with a healthcare professional if you’re unsure. Different types of medications offer varying degrees of pain relief and can have different side effects, so it’s important to choose the option that aligns with your specific needs. Consider factors such as the duration of the relief, how often the medication should be taken, and if there are any ingredients that may conflict with other medications or supplements you are taking.
Are you tired of suffering through the aches and pains of arthritis? Do you want to know more about the best OTC meds available to help ease your symptoms? In this article, we’ll cover all the important factors you need to consider before making a purchase, so you can feel confident in finding a medication that will help you feel your best. Plus, we’ll answer the most commonly asked questions about OTC arthritis medicines, so you’re fully informed on all the options available to you.
10 Best Otc Meds For Arthritis
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This product is ideal for providing relief from pain and reducing fever with its extra strength formula.
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2
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This product provides topical pain relief for muscles and joints from various sources such as arthritis, backache, strains, bruises, and sprains.
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3
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The product is ideal for providing pain relief associated with sore muscles, arthritis, simple backaches, and joint pain.
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4
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The product is ideal for relieving back pain and cramps, and is eligible for FSA/HSA reimbursement, with auto shut off and washable features.
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5
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This product provides targeted heat therapy for arthritis and other aches and pains.
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6
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Ideal for providing long-lasting pain relief with a combination of two active ingredients.
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7
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The product is ideal for pain relief and is enteric coated to prevent stomach irritation.
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8
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The product is ideal for relieving back and muscle pain.
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9
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The product is ideal for promoting healthy inflammation response and herbal pain relief.
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10
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It is an ideal pain reliever that provides fast acting relief for various types of pain.
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1. 500 Count Amazon Pain Relief Caplets

Amazon Basic Care Extra Strength Pain Relief provides effective relief for minor aches and pains. This pain reliever is formulated with Acetaminophen, 500 mg, which is the active ingredient in Extra Strength Tylenol Caplets. These caplets are designed to temporarily relieve minor pains caused by various conditions such as the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps. Moreover, it also reduces fever.
Acetaminophen is a widely used pain reliever and fever reducer that can be taken by adults and children 12 years and over. Pain can be caused by a variety of reasons, such as an injury, illness, or even poor sleep posture. Acute pain, on the other hand, is a sharp, sudden pain that acts as an alarm, such as when you stub your toe or get stung by a bee.
Amazon Basic Care Extra Strength Pain Relief provides fast-acting relief for both minor aches and acute pain. It is an effective solution for anyone looking for a reliable pain reliever that provides long-lasting relief. With each caplet containing 500 mg of Acetaminophen, this pain reliever is safe and easy to use.
2. Pro Menthol Roll-On Gel – Muscle & Joint Relief

The Biofreeze Professional roll-on is a top-rated solution for those seeking relief from aches and pains. It is the #1 clinically recommended menthol topical pain relief brand according to a recent survey by IPSOS Clinician in July 2022.
This fast-acting and long-lasting formula penetrates deep to provide cooling menthol pain relief for sore muscles, backaches, sore joints, bruises, and arthritis. The Biofreeze Professional roll-on is ideal for minor aches and pains associated with simple backache, arthritis, strains, bruises, and sprains.
The 3 fl oz roll-on applicator allows for hands-free application with its roller ball, making it easy to use without the mess. Additionally, the Biofreeze Professional roll-on is TSA-friendly, making it perfect for travel and on-the-go relief.
Biofreeze is FSA/HSA eligible, offering customers up to 30% savings on their purchase. This clinically recommended brand is trusted by a variety of healthcare professionals, including pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers.
With Biofreeze Professional roll-on, you can experience fast-acting pain relief without the hassle. Try it today and feel the difference it can make for your minor aches and pains.
3. Biofreeze Professional Pain Relief Gel Pack (3 Tubes)

Biofreeze Professional Menthol Pain Relieving Gel is a top-rated pain relief product that is clinically recommended by healthcare professionals. According to a survey conducted by IPSOS Clinician in July 2022, Biofreeze is the #1 Menthol Topical Pain Relief Brand that is highly recommended by clinicians.
This gel formula is easy to apply and quickly penetrates the skin to deliver effective pain relief. It is specially formulated with a cooling menthol formula that provides long-lasting relief for sore muscles, joint pain, arthritis, bruises, and simple backaches.
The 4 fl oz gel tube is one of the most popular formats for Biofreeze and is perfect for application on both small and large muscle areas. It is trusted by healthcare professionals such as pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers.
Biofreeze is eligible for FSA/HSA, which means you can save up to 30% when you purchase this product. Moreover, it is made with USP grade menthol and does not contain NSAIDs, making it a safer and more effective option for pain relief.
This product is not tested on animals, making it an ethical choice for conscious consumers. With Biofreeze, you can trust that you are using a high-quality, clinically recommended product that will provide fast and effective pain relief.
4. Tabby Gray Heat Pad: Fsa Eligible Relief!

The Geniani Heating Pad is the ultimate solution for muscle pain relief that delivers a stream of heat to the affected area, eases back pain, unbearable cramps, and provides pleasant muscle relaxation. This heating pad for neck and shoulders is ultra-soft, giving you that awesome cozy feeling, wherever you put it. The flexible microplush adapts to your body shape for maximum effect, making it the plushest piece of heaven for aching muscles.
The Geniani heating pad provides a low, medium, or high-temperature mode, allowing you to manage heat as per your needs. You can pick the most comfortable one and get the results you expect. The heating pads for cramps are designed to cater to your comfort and healing needs in the best possible way.
The Geniani XL size heating pad measures 12"x 24", making it the ideal heating pad for back pain that requires easy care. It’s machine washable, and the large heating pads come with an auto shut off, ensuring your safety and peaceful rest. You can trust the Geniani heating pad to deliver high-quality performance while keeping safety a top priority.
The Geniani heating pad is FSA/HSA eligible, making it a smart investment for your health needs. Additionally, it comes with a 3-year warranty and easy replacement, ensuring hassle-free usage and peace of mind. Should you experience any issues, feel free to address them, and the Geniani team will tackle them the very same day!
5. Thermophore Maxheat Arthritis Pad Moist Heating Pad Size Large 14" X 27" – Model 155

The Thermophore pad is a top-rated heating pad that provides maximum comfort and pain relief with its intense penetrating moist heat. It is designed to be safe and effective, with thermostat controlled technology that ensures the highest levels of heat are delivered without compromising safety. Unlike other popular heating pads, the Thermophore pad has an embedded thermostat that allows it to work at higher temperatures.
This heating pad is our #1 bestseller, and for good reason. It features a Three-Temperature Constant-Comfort Switch that allows users to choose the level of heat that's right for them. The switch also includes a 25-minute auto-off timer for added safety and peace of mind.
At 14" x 27", the Thermophore pad is larger than most standard heating pads, making it ideal for use on larger areas of the body. Despite its size, it heats up quickly and produces intense moist heat that helps to soothe sore muscles and joints. And because it doesn't require water, it's easy to use and clean.
6. Ultimate Pain Relief: Advil Dual Action Combo

Looking for a pain relief solution that targets pain at the source and provides overnight relief? Look no further than Advil Dual Action with Acetaminophen Caplets! This bottle of 144 caplets features a unique combination of 250 mg ibuprofen and 500 mg acetaminophen per dose (equivalent to 2 doses) to provide fast-acting, long-lasting relief from pain.
Not only does Advil Dual Action provide superior pain relief, but it also features new packaging that uses 20 percent less plastic, keeping nearly 500,000 pounds of plastic out of landfills. This pain relief medication is designed to relieve pain with ibuprofen and block pain signals with acetaminophen, making it a one-of-a-kind solution for all your pain relief needs.
If you're also struggling with sleeplessness, the 2-count sample of Advil PM included in this package can help. Combining the number one selling ibuprofen brand with 400 mg ibuprofen and the number one selling sleep medicine with 76 mg diphenhydramine citrate, Advil PM caplets provide relief from both pain and sleeplessness. These caplets provide 8 hours of pain relief and help you sleep soundly through the night.
Advil Dual Action is the first and only pain relief medication with a combination of acetaminophen and ibuprofen. It is a trusted and reliable brand that has been providing pain relief for years. So, whether you're struggling with a headache, toothache, or any other type of pain, Advil Dual Action with Acetaminophen Caplets is the perfect solution for you.
7. Aspirin Regimen Bayer 81mg Enteric Coated Tablets | Pain Reliever |300 Count

Bayer Aspirin is a trusted brand that helps protect your heart from the risk of another heart attack or clot-related (ischemic) stroke. When taken as directed by your doctor, it helps reduce the chance of a second heart attack by 31%. This makes it an ideal choice for adults who have been recommended a low dose aspirin regimen by their doctors.
Bayer Aspirin is the #1 doctor recommended aspirin brand, providing you with the assurance that it is a reliable and effective solution for your heart health. The tablets are easy to swallow, thanks to their safety coating, which also helps protect your stomach. Additionally, they are caffeine-free and sodium-free, making them a safe choice for those with dietary restrictions.
It's important to note that Bayer Aspirin should always be taken as directed by your doctor as it can have potential side effects for some individuals. However, if you are someone looking for a trusted and effective solution to protect your heart health, Bayer Aspirin is an excellent choice. With its proven track record in helping prevent future heart attacks and strokes, it's an investment in your health that you can feel confident in making.
8. Aleve Back & Muscle Pain Relief Naproxen Sodium Tablets ‐ 250 Count, 250 Count

Looking for fast and effective pain relief for your minor back and muscle aches? Look no further than Aleve Back and Muscle Pain Tablets. These round tablets are easy to swallow, making them a convenient option for anyone experiencing pain or discomfort.
But convenience isn't the only benefit of these tablets. Each tablet packs a powerful punch, providing up to 12 hours of targeted relief for your muscle and back pain. This long-lasting pain relief means you can get back to your daily activities without the distraction of nagging pain.
In addition to being effective, Aleve Back and Muscle Pain Tablets are also child-resistant, ensuring that they stay out of the hands of curious little ones.
So why suffer through minor back and muscle aches when relief is just a tablet away? Try Aleve Back and Muscle Pain Tablets today and experience the fast, targeted pain relief you need to get back to your best self.
9. Zyflamend 10-In-1 Joint & Pain Supplement

Zyflamend is a herbal supplement that offers relief from occasional pain by addressing it at its source. It supports a healthy response to pain and promotes overall joint health by supporting mobility, joint function, and healthy inflammation response. Unlike other popular joint supplements such as Glucosamine and chondroitin that only affect structure, Zyflamend is designed to handle inflammation that can lead to joint pain.
Zyflamend contains a potent blend of 10 superfood herbs that work together to provide maximum benefits. These herbs include Turmeric, Rosemary, Green Tea, and Ginger, among others. The unique combination of these herbs makes Zyflamend the top-selling joint supplement on the market.
What sets Zyflamend apart from other pain relievers is that it is the first herbal pain reliever to be Non-GMO Project Verified. It is also 100% vegetarian, certified gluten-free, and contains no synthetic fillers, DLPA, animal enzymes or byproducts, or artificial preservatives.
If you are looking for a natural and effective way to support your joint health, Zyflamend is the way to go. With its powerful herbs and unique formula, it is a trusted choice for those looking to reduce occasional pain and promote overall joint health.
10. Tylenol Rapid Release Gels (290 Ct.) (Pack Of 2)

The gelcaps of this pain reliever contain 500mg of acetaminophen, making it a potent and effective solution for anyone experiencing minor aches and pains. Whether it's a headache, muscle soreness, or menstrual cramps, this pain reliever can provide temporary relief. Additionally, it can also help reduce fever, making it an all-in-one solution for those feeling under the weather. With its easy-to-swallow gelcap form, it's a convenient and fast-acting remedy that can be taken anywhere, at any time. If you're looking for a reliable and fast-acting pain reliever, this product is a fantastic choice.
Best Otc Meds For Arthritis FAQs
Are there any natural OTC remedies for arthritis?
Yes, there are natural over-the-counter (OTC) remedies for arthritis that can provide relief from joint pain and inflammation. Some of these remedies include:
1. Glucosamine and Chondroitin: These supplements are commonly taken together to help rebuild cartilage and reduce joint pain.
2. Omega-3 Fatty Acids: Found in fish oil supplements, omega-3 fatty acids can reduce inflammation and improve joint mobility.
3. Turmeric: A spice commonly used in Indian cuisine, turmeric contains curcumin, a compound with anti-inflammatory properties that can help reduce joint pain.
4. Ginger: Another spice with anti-inflammatory properties, ginger can help reduce joint pain and stiffness.
5. Capsaicin: A compound found in chili peppers, capsaicin can reduce pain by blocking the transmission of pain signals to the brain.
It's important to note that these natural remedies may not work for everyone and may interact with other medications, so it's best to consult with a healthcare professional before trying them. Additionally, they may take longer to have an effect compared to traditional pain relievers, so patience is key.
Are there any OTC medications that can improve joint function in arthritis patients?
Yes, there are over-the-counter (OTC) medications that can improve joint function in arthritis patients. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to relieve pain and inflammation associated with arthritis. Some examples of OTC NSAIDs include ibuprofen (Advil, Motrin) and naproxen (Aleve). These medications work by blocking certain enzymes in the body that cause inflammation and pain.
Another OTC medication that can improve joint function in arthritis patients is acetaminophen (Tylenol). While it is not an NSAID and does not reduce inflammation, it can help to relieve pain.
Glucosamine and chondroitin supplements are also OTC options that some arthritis patients find helpful. These supplements are thought to help improve joint function by reducing inflammation and supporting the growth of cartilage.
It is important to note that while these OTC medications can provide relief for some arthritis patients, they may not work for everyone and can have side effects. It is always best to speak with a healthcare provider before starting any new medication or supplement.
Can OTC medications interact with prescription arthritis medications?
Yes, over-the-counter (OTC) medications can interact with prescription arthritis medications. Some OTC medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin and ibuprofen, may interact with prescription NSAIDs and increase the risk of stomach ulcers and bleeding. Additionally, some OTC medications like acetaminophen may interact with prescription medications that contain acetaminophen and increase the risk of liver damage. It is important to talk to your healthcare provider or pharmacist before taking any OTC medications, especially if you are taking prescription arthritis medications. They can help you determine if there are any potential interactions and recommend alternative medications if necessary. It is also important to read the labels of all medications, both prescription and OTC, and follow the dosage instructions carefully. If you experience any side effects or adverse reactions, be sure to report them to your healthcare provider immediately.
Can OTC pain relievers reduce inflammation associated with arthritis?
Yes, over-the-counter (OTC) pain relievers can help reduce inflammation associated with arthritis. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, aspirin, and naproxen can be effective in reducing pain and inflammation in the joints. These medications work by inhibiting the production of prostaglandins, which are chemicals that cause pain, swelling and inflammation.
While OTC pain relievers can be helpful in managing arthritis symptoms, they do not treat the underlying cause of the condition. It is important to speak with a healthcare provider about developing a comprehensive treatment plan, which may include medication, physical therapy, and lifestyle changes.
It is also important to follow the instructions on the label and take the recommended dose of OTC pain relievers. Overuse or misuse of these medications can lead to side effects such as stomach ulcers, kidney damage, and increased risk of heart attack or stroke.
Can OTC supplements like glucosamine and chondroitin help with arthritis symptoms?
There is some evidence to suggest that over-the-counter (OTC) supplements such as glucosamine and chondroitin can help manage arthritis symptoms. These supplements are commonly used by people with osteoarthritis, the most common form of arthritis, which occurs when the protective cartilage that cushions the joints wears down over time, causing pain and stiffness.
Glucosamine and chondroitin are both natural compounds found in cartilage, and some studies suggest that they may help reduce inflammation in the joints and improve joint function. However, the evidence is mixed, and some studies have found no significant difference between these supplements and a placebo.
It's important to note that these supplements can take several weeks or even months to have an effect, and they may not work for everyone. Additionally, they may interact with other medications, so it's important to speak with a healthcare provider before starting any new supplement regimen.
Overall, while there is some evidence to suggest that glucosamine and chondroitin may be helpful for managing arthritis symptoms, it's important to approach these supplements with caution and consult a healthcare provider before use.
How do I choose the right OTC medication for my specific type of arthritis?
Choosing the right over-the-counter (OTC) medication for your specific type of arthritis can be a daunting task, but it is essential to manage your symptoms effectively. Firstly, it is vital to identify the type of arthritis you have. Osteoarthritis (OA) and Rheumatoid Arthritis (RA) are the most common types of arthritis. Once you know your type of arthritis, it's time to consider the medication options available in the market. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to manage arthritis pain and inflammation. However, not all NSAIDs are suitable for everyone. Some people may experience stomach upset or other side effects. Acetaminophen is another medication that can be used to relieve pain. It is a good option for people who cannot take NSAIDs. Topical creams and gels containing capsaicin, menthol, or salicylates can also be used for pain relief. It is always advisable to consult with your doctor or a pharmacist before taking any OTC medication. They can help you choose the right medication based on your specific needs, medical history, and other medications you may be taking.
Is it safe to take multiple OTC medications for arthritis pain relief?
Taking multiple over-the-counter (OTC) medications for arthritis pain relief can be safe if you follow the recommended doses and do not exceed the maximum daily limit. However, it is always advisable to consult with your doctor or pharmacist before taking any medication, especially if you have any underlying health conditions or are taking prescription medications.
It is important to recognize that different medications may have different mechanisms of action and can interact with each other, potentially leading to adverse effects. For example, nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin can increase the risk of gastrointestinal bleeding when taken in combination with other NSAIDs or blood thinners. Similarly, acetaminophen can cause liver damage when taken in excess or with alcohol.
Therefore, it is crucial to read the labels carefully and follow the instructions provided by your healthcare provider or the manufacturer. If you experience any adverse effects or are unsure about the safety of combining medications, seek medical advice immediately.
What are the best OTC topical creams for arthritis pain?
Arthritis is a common condition that affects millions of people worldwide, causing pain, stiffness, and inflammation in the joints. Fortunately, there are several over-the-counter (OTC) topical creams that can help alleviate arthritis pain.
One of the most effective OTC creams for arthritis pain is capsaicin cream, which contains an active ingredient derived from chili peppers that can help block pain signals in the body. Another popular option is topical NSAIDs such as ibuprofen or diclofenac, which work by reducing inflammation and pain in the affected joints.
Other OTC creams that can help relieve arthritis pain include menthol-based creams, which create a cooling sensation that can help ease pain and inflammation, and topical salicylates, which contain an active ingredient similar to aspirin and can help reduce pain and swelling.
Ultimately, the best OTC cream for arthritis pain may vary depending on the individual and the severity of their symptoms. It is always advisable to speak with a healthcare professional before starting any new treatment regimen for arthritis pain.
What are the most effective over-the-counter medications for arthritis pain?
There are several over-the-counter medications that can be effective in managing arthritis pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and naproxen can help reduce pain and inflammation. Acetaminophen, which is not an NSAID, can also be effective in reducing pain, but does not have anti-inflammatory properties. Topical creams and gels containing ingredients such as capsaicin or menthol can provide localized pain relief.
It is important to note that while these medications can be helpful in managing arthritis pain, they should be used with caution and under the guidance of a healthcare provider. Long-term use of NSAIDs can have side effects such as stomach ulcers and kidney damage, and acetaminophen can be harmful in high doses. It is also important to consider potential interactions with other medications and to follow the recommended dosage instructions on the label. In addition to medication, lifestyle changes such as exercise, weight management, and stress reduction can also be effective in managing arthritis pain.
Which OTC medications are best for rheumatoid arthritis?
Over-the-counter (OTC) medications can be helpful for managing the symptoms of rheumatoid arthritis (RA). However, it is important to note that OTC medications cannot cure RA and should not be used as a substitute for prescribed medications.
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to relieve pain and reduce inflammation in RA. Ibuprofen, naproxen, and aspirin are examples of OTC NSAIDs. These medications can be effective in reducing pain and inflammation, but long-term use can increase the risk of gastrointestinal bleeding and other side effects.
Acetaminophen (paracetamol) is another OTC medication that can be used to relieve pain in RA. However, it does not have anti-inflammatory properties and does not help reduce inflammation.
Topical creams and gels containing capsaicin or menthol can also be used to alleviate pain and stiffness in RA. These products work by numbing the nerves in the affected areas.
It is important to talk to a healthcare provider before taking any OTC medications for RA to ensure they are safe and appropriate for an individual’s specific needs.