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15 Best Non Prescription Flea Medicine For Dogs (2023 Updated)

There are a few different types of non prescription flea medicine for dogs. Some of the most common include spot on treatments, oral treatments, and shampoos. Spot on treatments are applied directly to the dog’s skin, usually between the shoulder blades.

Oral treatments are usually given once a month and are taken by the dog like a treat. Shampoos are also used to kill fleas and can be applied directly to the dog’s coat.

15 Best Non Prescription Flea Medicine For Dogs

Product Image Product Name Features Price

Seresto Flea & Tick Collar for Small Dogs, 8 Month Prevention

  • Provides 8-months of continuous flea and tick prevention
  • Seresto flea and tick collar for small dogs works through contact, so fleas and ticks do not have to bite your dog to die

K9 Advantix II Flea, Tick & Mosquito Prevention for Medium Dogs 11-20 lbs , 6-Month

  • 6 monthly applications of K9 Advantix II flea and tick prevention for medium dogs weighing 11-20 pounds
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die

Nexgard 4-10 lbs 6 Doses for Pets

  • Possible side effects.
  • If you miss giving a dose, give it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Do not double the dose.

Vectra 3D Blue 3 Dose for Dogs 21-55 lbs

  • Can be used on Dogs and puppies 8 weeks of age and older.
  • Monthly dose repels and kills fleas, ticks, mosquitoes, biting and sand flies, lice and mites (excluding mange mites).

Frontline Spot on Small Dog 0-10kg 3 Pipettes

  • Helps to kill ticks on your pooch within 48 hours
  • Contains well known active ingredients including fipronil
  • Helps to kill lice and can also be used in pregnant and lactating dogs

Vet's Best Flea Itch Relief Shampoo – 16 oz.

  • Calming blend is completely free of irritating solvents
  • Pure extracts of orange and lemon to clean and give fast itch relief from flea infestation

PetArmor 7-Way Deworm Dog Insect Treatment for Dogs, Tablets – 2 count

  • Dipylidium Caninum- The most common tape , Taenia Pisiformis; Round s.
  • Toxacara Canis, Toxascaris Leonina; Hook s.
  • Ancylostoma Caninum, Ancylostoma Braziliense, Uncinaria Stenocephala.

Now Foods Flea & Tick Spray for Dogs – 8 fl. oz.

  • CERTIFICATIONS/CLASSIFICATIONS: SLS Free, Paraben Free.
  • Packaged in the USA by a family owned and operated company since 1968.

Advocate Small Dog Upto 4kg 3 Pack

  • Small Advocate provides dogs up to 4kg treatment and prevention of fleas and reduces the incidence of flea allergy dermatitis.

Bravecto Topical Solution for Dogs – 44-88 lbs (2 Tubes)

  • 112.5 mg fluralaner; 9.9-22 lbs.
  • 25 mg fluralaner; 22-44 lbs.
  • 500 mg fluralaner; 44-88 lbs.

Credelio (lotilaner) 6 Chewable Tablets for Dogs 25.1-50lbs

  • Once a month beef-flavored chewable tablet that is highly palatable
  • Kills adult fleas and treats flea infestations from Ctenocephalides felis

Advantage Multi for Dogs 9.1-20 lbs

  • Prescription topical protects your dog from heartworm disease
  • Treats circulating microfilariae
  • Kills adult fleas

Comfortis Chewable Tablets for Dogs & Cats, 140 mg – 6 count

  • Comfortis comes in a convenient, beef-flavored chewable
  • Starts to kill fleas within 30 minutes and protection lasts an entire month

Revolution for Dogs

  • Revolution (Brown) for Small Dogs 5-10 kg (10.1 – 20 lbs).
  • Key Benefits.
  • Dosage and Administration.
Seresto Flea & Tick Collar for Small Dogs, 8 Month Prevention
  • Provides 8-months of continuous flea and tick prevention
  • Seresto flea and tick collar for small dogs works through contact, so fleas and ticks do not have to bite your dog to die
K9 Advantix II Flea, Tick & Mosquito Prevention for Medium Dogs 11-20 lbs , 6-Month
  • 6 monthly applications of K9 Advantix II flea and tick prevention for medium dogs weighing 11-20 pounds
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
Nexgard 4-10 lbs 6 Doses for Pets
  • Possible side effects.
  • If you miss giving a dose, give it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Do not double the dose.
Vectra 3D Blue 3 Dose for Dogs 21-55 lbs
  • Can be used on Dogs and puppies 8 weeks of age and older.
  • Monthly dose repels and kills fleas, ticks, mosquitoes, biting and sand flies, lice and mites (excluding mange mites).
Frontline Spot on Small Dog 0-10kg 3 Pipettes
  • Helps to kill ticks on your pooch within 48 hours
  • Contains well known active ingredients including fipronil
  • Helps to kill lice and can also be used in pregnant and lactating dogs
Vet's Best Flea Itch Relief Shampoo – 16 oz.
  • Calming blend is completely free of irritating solvents
  • Pure extracts of orange and lemon to clean and give fast itch relief from flea infestation
PetArmor 7-Way Deworm Dog Insect Treatment for Dogs, Tablets – 2 count
  • Dipylidium Caninum- The most common tape , Taenia Pisiformis; Round s.
  • Toxacara Canis, Toxascaris Leonina; Hook s.
  • Ancylostoma Caninum, Ancylostoma Braziliense, Uncinaria Stenocephala.
Now Foods Flea & Tick Spray for Dogs – 8 fl. oz.
  • CERTIFICATIONS/CLASSIFICATIONS: SLS Free, Paraben Free.
  • Packaged in the USA by a family owned and operated company since 1968.
Advocate Small Dog Upto 4kg 3 Pack
  • Small Advocate provides dogs up to 4kg treatment and prevention of fleas and reduces the incidence of flea allergy dermatitis.
Bravecto Topical Solution for Dogs – 44-88 lbs (2 Tubes)
  • 112.5 mg fluralaner; 9.9-22 lbs.
  • 25 mg fluralaner; 22-44 lbs.
  • 500 mg fluralaner; 44-88 lbs.
Credelio (lotilaner) 6 Chewable Tablets for Dogs 25.1-50lbs
  • Once a month beef-flavored chewable tablet that is highly palatable
  • Kills adult fleas and treats flea infestations from Ctenocephalides felis
Advantage Multi for Dogs 9.1-20 lbs
  • Prescription topical protects your dog from heartworm disease
  • Treats circulating microfilariae
  • Kills adult fleas
Comfortis Chewable Tablets for Dogs & Cats, 140 mg – 6 count
  • Comfortis comes in a convenient, beef-flavored chewable
  • Starts to kill fleas within 30 minutes and protection lasts an entire month
Revolution for Dogs
  • Revolution (Brown) for Small Dogs 5-10 kg (10.1 – 20 lbs).
  • Key Benefits.
  • Dosage and Administration.

1. Seresto Flea & Tick Collar for Small Dogs, 8 Month Prevention

Seresto Flea & Tick Collar for Small Dogs, 8 Month Prevention

  • Provides 8-months of continuous flea and tick prevention
  • Seresto flea and tick collar for small dogs works through contact, so fleas and ticks do not have to bite your dog to die
  • Veterinarian-recommended flea and tick prevention for dogs in a convenient, odorless non-greasy collar; No need for messy monthly treatments

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Amazon
Redpost Equestrian

Product Details

Specifications

Details
Season Core

2. K9 Advantix II Flea, Tick & Mosquito Prevention for Medium Dogs 11-20 lbs , 6-Month

K9 Advantix II Flea, Tick & Mosquito Prevention for Medium Dogs 11-20 lbs , 6-Month

  • 6 monthly applications of K9 Advantix II flea and tick prevention for medium dogs weighing 11-20 pounds
  • K9 Advantix II flea and tick prevention for dogs works through contact, so fleas, ticks and mosquitoes do not have to bite your dog to die
  • K9 Advantix II flea and tick control for dogs is an easy to apply topical formula
  • Starts working to kill fleas within 12 hours and keeps working for 30 days
  • Suitable for effective year-round dog flea and tick treatment for medium dogs

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eBay
Beazox Store

Product Details

Specifications

Details
Release Date 02-05-2007
Package Dimensions 7.7 x 4.3 x 1.5 inches

3. Nexgard 4-10 lbs 6 Doses for Pets

Nexgard 4-10 lbs 6 Doses for Pets

  • Possible side effects.
  • If you miss giving a dose, give it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Do not double the dose.

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Amazon
Walmart – Walmart Pet RX
Allivet Pet Pharmacy
Chewy.com

Product Details

Specifications

Details
For Use With Dogs
Administration Form Oral
Breed Size Extra Small Breeds
Product Form Chew
Strength 11.3 mg Afoxolaner
Drug Type Parasiticide

Reviews From Real Customers

Settles Fur Babies

4. Vectra 3D Blue 3 Dose for Dogs 21-55 lbs

Vectra 3D Blue 3 Dose for Dogs 21-55 lbs

  • Can be used on Dogs and puppies 8 weeks of age and older.
  • Monthly dose repels and kills fleas, ticks, mosquitoes, biting and sand flies, lice and mites (excluding mange mites).
  • Long Lasting, quick drying, convenient topical treatment with patented applicator. Remains effective after bathing or swimming.
  • Each monthly dose controls development of all flea stages; Prevents, controls and stops flea infestation and prevents re-infestation.

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Amazon
Walmart – Pets with Panache Inc
Sears
EntirelyPets.com

Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Product Dimensions 2 x 5 x 8 inches; 1.59 Ounces
Item Package Dimensions L x W x H 5.3 x 4.9 x 1.1 inches
Item Dimensions LxWxH 2 x 5 x 8 inches
Target Audience Keyword Dogs
Age Range Description All Stages

Reviews From Real Customers

Erika Y
Teresa P.

5. Seresto 8 Month Flea & Tick Prevention Collar for Large Dogs 2 Count

Seresto 8 Month Flea & Tick Prevention Collar for Large Dogs 2 Count

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Petco.com
HealthyPets.com
EntirelyPets.com

Product Details

Specifications

Details
Product Length 5 inches
Active Ingredient(s) Flumethrin 4.5 Pct., Imidacloprid 10%
Age/Weight Restrictions 7 weeks and older
Medication Type Non-Prescription
Number of Doses 2
Pet Size Large Dog
Pet Type Dog
Pet Weight Range 18lbs and over
Product Width 3.125 inches
Targeted Insect(s) Fleas and Ticks

Reviews From Real Customers

Ms Tee
Gabby15
Ray dog musher

6. Frontline Spot on Small Dog 0-10kg 3 Pipettes

Frontline Spot on Small Dog 0-10kg 3 Pipettes

  • Helps to kill ticks on your pooch within 48 hours
  • Contains well known active ingredients including fipronil
  • Helps to kill lice and can also be used in pregnant and lactating dogs
  • Suitable for dogs that are older than 8 weeks of age and weigh more than 2 kg

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Redpost Equestrian

Product Details

Specifications

Details
Animal Type Dog

7. Vet’s Best Flea Itch Relief Shampoo – 16 oz.

Vet's Best Flea Itch Relief Shampoo - 16 oz.

  • Calming blend is completely free of irritating solvents
  • Pure extracts of orange and lemon to clean and give fast itch relief from flea infestation
  • Micronized oatmeal is absorbed quickly to soothe and soften irritated skin
  • Made in the usa

Product Details

Specifications

Details
Fluid Ounces 16 oz
Hair Product Form Liquids
Product Net Content UOM Fluid Ounces
Duration NOT STATED
Count 1
Multipack Quantity 1
Dimensions 2.5 x 2.5 x 8.5 inches
Pet Size Medium (26-50 lbs)
Piece Count 1
Count Per Pack 1
Form Liquids
Container Type Bottle
Animal Type Dog
Assembled Product Weight 1.06 lbs

Reviews From Real Customers

hankaroo
CharlottesMomma

8. PetArmor 7-Way Deworm Dog Insect Treatment for Dogs, Tablets – 2 count

PetArmor 7-Way Deworm Dog Insect Treatment for Dogs, Tablets - 2 count

  • Dipylidium Caninum- The most common tape , Taenia Pisiformis; Round s.
  • Toxacara Canis, Toxascaris Leonina; Hook s.
  • Ancylostoma Caninum, Ancylostoma Braziliense, Uncinaria Stenocephala.

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eBay
Walmart
Chewy.com

Product Details

Specifications

Details
Units in Package 2
Directions Directions for Use: For the removal of large roundworms, hookworms and tapeworms in adult dogs or young dogs, weighing more than 25 lbs., administer these tablets according to the weight of the animal. 6.0 lbs to 25.0 lbs: Use the 30 mg size. 25.1 lbs to 50 lbs: Give 1 tablet. 50.1 lbs to 100 lbs: Give 2 tablets. 100.1 lbs to 150 lbs: Give 3 tablets. 150.1 lbs to 200 lbs: Give 4 tablets. Note: For puppies or small dogs weighing less than 25 lbs., use 7 Way De-Wormer Chewable Flavored Dog De-Wormer Tablets for puppies and small dogs. 7 Way De-Wormer Chewables are recommended for dogs 12 weeks of age and older. Offer the proper dosage by hand or in the dog’s food container, with our without food. Do not withhold food from your dog prior to or after treatment. Recommended De-Worming Schedule: Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasitism. De-worming schedules may vary depending on the climate where you live and the activity of your dog.
Ingredients Active Ingredients: Each Flavored Chewable Contains 114 mg Pyrantel Pamoate and 114 mg Praziquantel.
Warnings Keep out of reach of children. For use only as directed on package insert & back panel. Precaution: The safety of 7 Way De-Wormer in breeding dogs and pregnant bitches has not been determined. In case of ingestion by humans, contact a physician immediately. Physicians may contact a Poison Control Center for advice concerning cases of ingestion by humans. Not for human consumption. Store at controlled room temperature 59-86 degrees F (15-30 degrees C). In case of an emergency; call: 1-800-781-4738. Non-emergency; call: 1-800-224-pets (7387).

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ATs808

9. Now Foods Flea & Tick Spray for Dogs – 8 fl. oz.

Now Foods Flea & Tick Spray for Dogs - 8 fl. oz.

  • CERTIFICATIONS/CLASSIFICATIONS: SLS Free, Paraben Free.
  • Packaged in the USA by a family owned and operated company since 1968.

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Walmart
iHerb
PureFormulas.com

Product Details

Specifications

Details
Geranium Oil 0.76%
Lemongrass Oil 0.25%
Peppermint Oil 0.20%
Cinnamon Cassia Oil 0.16%
Cedarwood Oil 0.12
Thyme Oil 0.11%
Inert Ingredients* 98.4%

Reviews From Real Customers

AnnaNemchinova

10. Advocate Small Dog Upto 4kg 3 Pack

Advocate Small Dog Upto 4kg 3 Pack

  • Small Advocate provides dogs up to 4kg treatment and prevention of fleas and reduces the incidence of flea allergy dermatitis.
  • Larval flea stages are killed in the surrounding of Advocate treated pets and prevents heartworm infection (Dirofilaria immitis).
  • Product Details.

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Bonanza – Banyer

Product Details

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Andrew W.
Nyree W.

11. Bravecto Topical Solution for Dogs – 44-88 lbs (2 Tubes)

Bravecto Topical Solution for Dogs - 44-88 lbs (2 Tubes)

  • 112.5 mg fluralaner; 9.9-22 lbs.
  • 25 mg fluralaner; 22-44 lbs.
  • 500 mg fluralaner; 44-88 lbs.
  • 1000 mg fluralaner; 88-123 lbs.
  • 1400 mg fluralaner.

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Walmart – Walmart Pet RX
Chewy.com
Allivet Pet Pharmacy
PetMeds

Product Details

Specifications

Details
For Use With Dogs 44-88 lbs. Do not use on dogs under 4.4 lbs
Administration Form Topical
Breed Size Medium Breeds, Large Breeds
Product Form Solution
Strength 1000 mg Fluralaner
Drug Type Parasiticide

Reviews From Real Customers

Britty
DaveL

12. Credelio (lotilaner) 6 Chewable Tablets for Dogs 25.1-50lbs

Credelio (lotilaner) 6 Chewable Tablets for Dogs 25.1-50lbs

  • Once a month beef-flavored chewable tablet that is highly palatable
  • Kills adult fleas and treats flea infestations from Ctenocephalides felis
  • Starts killing fleas in 4 hours
  • Kills 98.7% of ticks within just 8 hours
  • Approved for dogs 8+ weeks of age, weighing more than 4.4 lbs

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Walmart – Walmart Pet RX
Allivet Pet Pharmacy
PetCareRx
Chewy.com

Product Details

Specifications

Details
For Use With Dogs – 8 weeks or older
Administration Form Oral
Breed Size Medium Breeds
Product Form Chewable Tablet
Strength 450 mg Lotilaner
Drug Type Parasiticide

Reviews From Real Customers

Lozard
Charity W
JenW

13. Advantage Multi for Dogs 9.1-20 lbs

Advantage Multi for Dogs 9.1-20 lbs

  • Prescription topical protects your dog from heartworm disease
  • Treats circulating microfilariae
  • Kills adult fleas

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Walmart
Chewy.com
Allivet Pet Pharmacy
Valley Vet Supply

Product Details

Specifications

Details
For Use With Dogs
Administration Form Topical
Breed Size Small Breeds
Product Form Solution
Strength 100 mg Imidacloprid and 25 mg Moxidectin
Drug Type Parasiticide

Reviews From Real Customers

Mary B
Rhouston52
Coffeehound

14. Comfortis Chewable Tablets for Dogs & Cats, 140 mg – 6 count

Comfortis Chewable Tablets for Dogs & Cats, 140 mg - 6 count

  • Comfortis comes in a convenient, beef-flavored chewable
  • Starts to kill fleas within 30 minutes and protection lasts an entire month
  • Spinosad, the active ingredient in Comfortis, is environmentally friendly

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Vet Approved RX

Product Details

Specifications

Details
Primary Brand Comfortis
For Pet Weight Max 10 LBS
For Pet Weight Min 4.1 LBS

Reviews From Real Customers

donna
Gingi

15. Revolution for Dogs

Revolution for Dogs

  • Revolution (Brown) for Small Dogs 5-10 kg (10.1 – 20 lbs).
  • Key Benefits.
  • Dosage and Administration.
  • The recommended minimum dose is 2.7 mg selamectin per pound (6 mg/kg) of body weight.

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Walmart – Walmart Pet RX
Allivet Pet Pharmacy
Chewy.com
Valley Vet Supply

Product Details

Specifications

Details
For Use With Dogs
Administration Form Topical
Breed Size Small Breeds
Product Form Solution
Strength 60 mg Selamectin
Drug Type Parasiticide

Reviews From Real Customers

DWESFam
zkid
Sandi

Conclusion

Some pet owners may prefer to use natural methods or home remedies to control fleas on their dogs, while others may choose to use over-the-counter (OTC) or prescription products. Some factors that may influence a pet owner’s decision include the severity of the flea infestation, the dog’s age and health, and personal preferences.

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