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20 Best Night Serum For 40S (2023 Updated)

A night serum for 40s is a great way to help keep your skin looking young and radiant. It can help to improve the appearance of fine lines and wrinkles, as well as help to even out your skin tone. A night serum can also help to hydrate your skin, which is important as you age.

20 Best Night Serum For 40S

Product Image Product Name Features Price

Derma E Night Serum, Anti-Wrinkle Vitamin A – 2 fl oz

  • CLINICALLY PROVEN, dermatologist recommended and fortified with Glycolic Acid to exfoliate the skin
  • ANTI-AGING SERUM helps to diminish the appearance of fine lines, wrinkles & dull skin

Ultimate Wrinkle Serum – Nighttime – Vitamin C – Retinol – MSM

  • 20% Vitamin C helps fight free radicals and diminish sun damage, dark-spots, and age lines for a younger, healthier look and feel

Strivectin Advanced Retinol Nightly Multi-Correct Serum

  • Ultra concentrated retinol serum for reducing fine lines
  • Reduces the look of wrinkles and fine lines
  • Restores firmness and elasticity for firmer & smooth skin

Estee Lauder Advanced Night Repair Serum Synchronized Multi-Recovery Complex – 1.0 oz

  • 1 oz

Elizabeth Arden Retinol Ceramide Capsules Line Erasing Night Serum 30

  • 30 Caps

All-in-One Anti Aging Night Serum for Sensitive Skin by Tree to Tub –

  • Sensitive, allergy-prone skin, eczema, psoriasis, dermatitis, rosacea. You name it! Skin Friendly pH.
  • Protect your skin with pH balanced formulas. Say goodbye to irritations! Natural Fragrance.

Olay Regenerist Night Serum, Retinol 24, Max – 40 ml

  • FRAGRANCE-FREE FACE SERUM: This fragrance-free serum absorbs quickly so you’re not left with a greasy feeling (or pillow)

Kiehl's Since 1851 Retinol Fast Release Wrinkle-Reducing Night Serum, 0.94 oz.

  • Anti-ageing serum powered by 0.3% retinol.
  • 100% of testers saw a reduction in wrinkles.
  • Reduces fine lines in as little as 5 days.

Olay Regenerist Night Serum, Fragrance-Free, Retinol 24 – 40 ml

  • Rejuvenate your skin with the help of this facial serum
  • Anti-aging properties help reduce visible signs of aging
  • Formulated to reduce dark spots and add brightness

Kiehl's Midnight Recovery Concentrate – 30ml/1oz bottle

  • 30 ml

Ahava – Time to Revitalize Extreme Night Treatment 1 oz.

  • 1.0 oz

Olay Regenerist Retinol24 Night Serum 40ml

  • 40 ml

Roc Multi Correxion Night Serum, Hydrate + Plump, Capsules – 30 capsules, 0.35 fl oz

  • 30 Pieces

Neostrata Comprehensive Retinol 0.3% Night Serum 30ml

  • Targets the skin’s hydrating matrix
  • Reduces the look of coarse wrinkles
  • Enhances skin tone, texture and an overall firmer appearance

Drunk Elephant T.L.C Framboos Glycolic Night Serum 1 Ounce

  • 1 oz/ 30 ml

Biossance Squalane + Copper Peptide Rapid Plumping Serum – 50 ml

  • 50 ml

The Organic Pharmacy Retinol Night Serum 30 ml

  • Boosts collagen.
  • Refines pores.
  • Corrects pigmentation.

SkinCeuticals Serum 20 AOX+ 1.0 fl. oz.

  • AOX+ advanced antioxidant technology helps provide a younger-looking skin
  • Comes with a dropper to let you conveniently dispense this serum

Philosophy Ultimate Miracle Worker Multi-Rejuvenating Nighttime Serum-In-Cream 1.7oz / 50ml

  • This serum-in-cream form helps provide a youthful glow to your skin
  • The advanced formula helps keep your skin moisturized for a smooth texture
Derma E Night Serum, Anti-Wrinkle Vitamin A – 2 fl oz
  • CLINICALLY PROVEN, dermatologist recommended and fortified with Glycolic Acid to exfoliate the skin
  • ANTI-AGING SERUM helps to diminish the appearance of fine lines, wrinkles & dull skin
Ultimate Wrinkle Serum – Nighttime – Vitamin C – Retinol – MSM
  • 20% Vitamin C helps fight free radicals and diminish sun damage, dark-spots, and age lines for a younger, healthier look and feel
Strivectin Advanced Retinol Nightly Multi-Correct Serum
  • Ultra concentrated retinol serum for reducing fine lines
  • Reduces the look of wrinkles and fine lines
  • Restores firmness and elasticity for firmer & smooth skin
Estee Lauder Advanced Night Repair Serum Synchronized Multi-Recovery Complex – 1.0 oz
  • 1 oz
Elizabeth Arden Retinol Ceramide Capsules Line Erasing Night Serum 30
  • 30 Caps
All-in-One Anti Aging Night Serum for Sensitive Skin by Tree to Tub –
  • Sensitive, allergy-prone skin, eczema, psoriasis, dermatitis, rosacea. You name it! Skin Friendly pH.
  • Protect your skin with pH balanced formulas. Say goodbye to irritations! Natural Fragrance.
Olay Regenerist Night Serum, Retinol 24, Max – 40 ml
  • FRAGRANCE-FREE FACE SERUM: This fragrance-free serum absorbs quickly so you’re not left with a greasy feeling (or pillow)
Kiehl's Since 1851 Retinol Fast Release Wrinkle-Reducing Night Serum, 0.94 oz.
  • Anti-ageing serum powered by 0.3% retinol.
  • 100% of testers saw a reduction in wrinkles.
  • Reduces fine lines in as little as 5 days.
Olay Regenerist Night Serum, Fragrance-Free, Retinol 24 – 40 ml
  • Rejuvenate your skin with the help of this facial serum
  • Anti-aging properties help reduce visible signs of aging
  • Formulated to reduce dark spots and add brightness
Kiehl's Midnight Recovery Concentrate – 30ml/1oz bottle
  • 30 ml
Ahava – Time to Revitalize Extreme Night Treatment 1 oz.
  • 1.0 oz
Olay Regenerist Retinol24 Night Serum 40ml
  • 40 ml
Roc Multi Correxion Night Serum, Hydrate + Plump, Capsules – 30 capsules, 0.35 fl oz
  • 30 Pieces
Neostrata Comprehensive Retinol 0.3% Night Serum 30ml
  • Targets the skin’s hydrating matrix
  • Reduces the look of coarse wrinkles
  • Enhances skin tone, texture and an overall firmer appearance
Drunk Elephant T.L.C Framboos Glycolic Night Serum 1 Ounce
  • 1 oz/ 30 ml
Biossance Squalane + Copper Peptide Rapid Plumping Serum – 50 ml
  • 50 ml
The Organic Pharmacy Retinol Night Serum 30 ml
  • Boosts collagen.
  • Refines pores.
  • Corrects pigmentation.
SkinCeuticals Serum 20 AOX+ 1.0 fl. oz.
  • AOX+ advanced antioxidant technology helps provide a younger-looking skin
  • Comes with a dropper to let you conveniently dispense this serum
Philosophy Ultimate Miracle Worker Multi-Rejuvenating Nighttime Serum-In-Cream 1.7oz / 50ml
  • This serum-in-cream form helps provide a youthful glow to your skin
  • The advanced formula helps keep your skin moisturized for a smooth texture

1. Derma E Night Serum, Anti-Wrinkle Vitamin A – 2 fl oz

Derma E Night Serum, Anti-Wrinkle Vitamin A - 2 fl oz

  • CLINICALLY PROVEN, dermatologist recommended and fortified with Glycolic Acid to exfoliate the skin
  • ANTI-AGING SERUM helps to diminish the appearance of fine lines, wrinkles & dull skin
  • POTENT ANTIOXIDANT blend of Retinol and Vitamin E work to renew and nourish the skin
  • SKIN-RENEWING SERUM keeps skins appearance soft & smooth for a radiant & healthier-looking complexion
  • Retinol: Anti-aging molecule helps to reduce the appearance of fine lines wrinkles and rough texture

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Amazon.com
eBay
Walmart
Ulta Beauty

Product Details

Specifications

Details
Derived Nutrition Claim Salt Free
Derived Nutrition Claim Soy Free
Derived Nutrition Claim Paraben Free
Derived Nutrition Claim Nitrite Free
Derived Nutrition Claim Vegan

Reviews From Real Customers

Derma E fan

2. Ultimate Wrinkle Serum – Nighttime – Vitamin C – Retinol – MSM

Ultimate Wrinkle Serum - Nighttime - Vitamin C - Retinol - MSM

  • 20% Vitamin C helps fight free radicals and diminish sun damage, dark-spots, and age lines for a younger, healthier look and feel
  • Clinical Strength, 2% Retinol, has over 700 PUBLISHED STUDIES showing its anti aging effects on skin
  • 10% MSM, which is necessary to both collagen and keratin, is a natural anti-inflammatory which helps keep the skin smooth and youthful

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Amazon.com – Seller
Walmart – Tree of Life Beauty

Product Details

Specifications

Details
Skin Tone All Skin Tones
Count Per Pack 1
Skin Type All
Multipack Quantity 1
Assembled Product Weight 0.2205 lb

3. Strivectin Advanced Retinol Nightly Multi-Correct Serum

Strivectin Advanced Retinol Nightly Multi-Correct Serum

  • Ultra concentrated retinol serum for reducing fine lines
  • Reduces the look of wrinkles and fine lines
  • Restores firmness and elasticity for firmer & smooth skin
  • Refines the look of skin textures and pores
  • Promotes healthy, radiant skin for a smoother finish

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Sold By Price
Amazon.com
eBay – 10qservice
StriVectin
Ulta Beauty

Product Details

Specifications

Details
Brand Details StriVectin
Product Consistency Serum
Skin Type All Skin Types
Application Area Face
Ingredient Dimethicone; Retinol; Shea Butter; Squalane Oil

Reviews From Real Customers

Carmine @.
Sunita

4. Estee Lauder Advanced Night Repair Serum Synchronized Multi-Recovery Complex – 1.0 oz

Estee Lauder Advanced Night Repair Serum Synchronized Multi-Recovery Complex - 1.0 oz

  • 1 oz

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Amazon.com – Seller
eBay
Estée Lauder Official Site
Sephora

Product Details

Specifications

Details
Item traits 0.1 fl oz
Country/Region of Manufacture United States
Skin Type All Skin Types
Formulation Serum
Main Purpose Age-Defying

5. Elizabeth Arden Retinol Ceramide Capsules Line Erasing Night Serum 30

Elizabeth Arden Retinol Ceramide Capsules Line Erasing Night Serum 30

  • 30 Caps

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Amazon.com
eBay
Walmart
Elizabeth Arden

Product Details

Specifications

Details
Country of Origin – Textiles USA
System of Measurement U.S. Customary
Count 1
Contained Battery Type 1
Multipack Quantity 1

Reviews From Real Customers

sabk1928
ryles.s
Laney123

6. All-in-One Anti Aging Night Serum for Sensitive Skin by Tree to Tub –

All-in-One Anti Aging Night Serum for Sensitive Skin by Tree to Tub -

  • Sensitive, allergy-prone skin, eczema, psoriasis, dermatitis, rosacea. You name it! Skin Friendly pH.
  • Protect your skin with pH balanced formulas. Say goodbye to irritations! Natural Fragrance.
  • No nasties or irritants. Just light, natural scents from pure essential oil.Clean Ingredients.
  • Only the purest, straight Mother Nature.Earth Friendly.
  • Always vegan, cruelty free, with recycled or recyclable plastic.

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Amazon.com – Seller
eBay – iherb
Sears – zabiva
iHerb

Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Product Dimensions 1.38 x 1.38 x 4.13 inches; 3 Ounces
Country of Origin Taiwan

7. Olay Regenerist Night Serum, Retinol 24, Max – 40 ml

Olay Regenerist Night Serum, Retinol 24, Max - 40 ml

  • FRAGRANCE-FREE FACE SERUM: This fragrance-free serum absorbs quickly so you’re not left with a greasy feeling (or pillow)
  • MAXIMIZED INGREDIENTS: Our Retinol 24 formula now in MAX, with 20% more Retinol 24 Hydrating Complex
  • MAX BEAUTY SLEEP: Massage evenly over your face and neck at night before moisturizer. Always use SPF in the daytime when using retinol
  • 24 HOUR TRANSFORMATION: Visibly smooths and brightens thanks to the Retinol 24 Hydrating Complex

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Amazon
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Walmart
OLAY.com

Product Details

Specifications

Details
Derived Nutrition Claim Salt Free
Derived Nutrition Claim Soy Free
Derived Nutrition Claim Paraben Free
Derived Nutrition Claim Nitrite Free
Derived Nutrition Claim Fragrance Free

Reviews From Real Customers

trisha.h
S1966
Sabiha2009

8. Kiehl’s Since 1851 Retinol Fast Release Wrinkle-Reducing Night Serum, 0.94 oz.

Kiehl's Since 1851 Retinol Fast Release Wrinkle-Reducing Night Serum, 0.94 oz.

  • Anti-ageing serum powered by 0.3% retinol.
  • 100% of testers saw a reduction in wrinkles.
  • Reduces fine lines in as little as 5 days.
  • Minimises wrinkles in just 2 weeks.
  • Increases skin cell turnover.

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Amazon
eBay
Kiehl’s
Sephora

Product Details

Specifications

Details
Good for Anti-Aging

9. Olay Regenerist Night Serum, Fragrance-Free, Retinol 24 – 40 ml

Olay Regenerist Night Serum, Fragrance-Free, Retinol 24 - 40 ml

  • Rejuvenate your skin with the help of this facial serum
  • Anti-aging properties help reduce visible signs of aging
  • Formulated to reduce dark spots and add brightness

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Amazon
eBay
Walmart
OLAY.com

Product Details

Specifications

Details
Product Type Night serum
Volume 1.3 fl oz
Fragrance-Free Yes
Suitable Skin Type Combination, Normal, Mature, Dry
Dye-Free Yes

Reviews From Real Customers

Stephanie1962

10. Kiehl’s Midnight Recovery Concentrate – 30ml/1oz bottle

Kiehl's Midnight Recovery Concentrate - 30ml/1oz bottle

  • 30 ml

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Amazon
Kiehl’s
Sephora
Ulta Beauty

Product Details

Specifications

Details
Skin Type Night Care
Count 1
Contained Battery Type 1
Multipack Quantity 1
Is Travel Size Y

Reviews From Real Customers

Katy the Spot Lover
redheadlondon
Katie

11. Ahava – Time to Revitalize Extreme Night Treatment 1 oz.

Ahava - Time to Revitalize Extreme Night Treatment 1 oz.

  • 1.0 oz

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Amazon
eBay
Walmart
Ahava

Product Details

Specifications

Details
Phthalates-Free Yes
Paraben-Free Yes
Sulfate-Free Yes
Suitable Skin Types Normal, Oily, Combination, Dry, Sensitive
Container Type Bottle

Reviews From Real Customers

Mel P.
Joyce Y.
Joanne W.

12. Olay Regenerist Retinol24 Night Serum 40ml

Olay Regenerist Retinol24 Night Serum 40ml

  • 40 ml

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Amazon
Perfumes Club US
BeautyTheShop

Product Details

Specifications

Details
Dye-Free Yes
Fragrance-Free Yes
Container Type Bottle
Volume 40 ml
Area of Application Face

13. Marie Veronique Gentle Retinol Night Serum 1 oz / 30 ml

Marie Veronique Gentle Retinol Night Serum 1 oz / 30 ml

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Amazon
Credo

Product Details

14. Roc Multi Correxion Night Serum, Hydrate + Plump, Capsules – 30 capsules, 0.35 fl oz

Roc Multi Correxion Night Serum, Hydrate + Plump, Capsules - 30 capsules, 0.35 fl oz

  • 30 Pieces

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Amazon
eBay
Walmart
Target

Product Details

Specifications

Details
Derived Nutrition Claim Salt Free
Derived Nutrition Claim Soy Free
Derived Nutrition Claim Paraben Free
Derived Nutrition Claim Nitrite Free
Derived Nutrition Claim Fragrance Free

Reviews From Real Customers

mzfreebz

15. Neostrata Comprehensive Retinol 0.3% Night Serum 30ml

Neostrata Comprehensive Retinol 0.3% Night Serum 30ml

  • Targets the skin’s hydrating matrix
  • Reduces the look of coarse wrinkles
  • Enhances skin tone, texture and an overall firmer appearance

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Amazon
NeoStrata
Sears
Life & Looks

Product Details

Specifications

Details
Featured Ingredients Hyaluronic Acid; Retinol; Vitamin E; Glycerin
Formulation Serum
Skin Type Mature; Sensitive; Dry; Oily; Combination; Normal

16. Drunk Elephant T.L.C Framboos Glycolic Night Serum 1 Ounce

Drunk Elephant T.L.C Framboos Glycolic Night Serum 1 Ounce

  • 1 oz/ 30 ml

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Walmart
Sephora

Product Details

Specifications

Details
Skin Type Normal, Dry, Combination, and Oily
Skincare Concerns Fine Lines and Wrinkles, Pores, and Dullness
Formulation Lightweight Serum
Salicylic Acid (BHA) Loosens sebum to unclog pores while soothing skin.
Raspberry Fruit Extract Rehydrates and soothes skin with antioxidants.

Reviews From Real Customers

michelle.e
Reviewer
Mamabee

17. Biossance Squalane + Copper Peptide Rapid Plumping Serum – 50 ml

Biossance Squalane + Copper Peptide Rapid Plumping Serum - 50 ml

  • 50 ml

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Amazon
eBay – cheaper.for.you
Biossance
Sephora

Product Details

Specifications

Details
Package Dimensions 4.17 x 1.97 x 1.93 inches; 5.93 Ounces
Country of Origin USA

Reviews From Real Customers

Samantha I.
Happy C.

18. The Organic Pharmacy Retinol Night Serum 30 ml

The Organic Pharmacy Retinol Night Serum 30 ml

  • Boosts collagen.
  • Refines pores.
  • Corrects pigmentation.
  • Reduces wrinkles and fine lines.
  • Apply one full dropper to face, neck and decolette every night after cleansing.

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Amazon
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Walmart
Naturisimo

Product Details

Specifications

Details
Aging Skin Fine Lines and Wrinkles, Loss of Firmness
Application Area Decollete, Face, Nails
Ideal for these Concerns Free Radical Damage
Preferences Certified Organic, Hypoallergenic, Natural
Skin Care Skin Care Treatments

Reviews From Real Customers

Heather M.
Gemma D.

19. SkinCeuticals Serum 20 AOX+ 1.0 fl. oz.

SkinCeuticals Serum 20 AOX+ 1.0 fl. oz.

  • AOX+ advanced antioxidant technology helps provide a younger-looking skin
  • Comes with a dropper to let you conveniently dispense this serum
  • UV-protection properties reduce the chances of premature aging

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eBay – leeyelashoc
SkinCeuticals
ExclusiveBeautyClub.com
Skin Type Solutions

Product Details

Specifications

Details
Applicator Type Dropper
Suitable Skin Types Normal, oily
Volume 1 fl oz
Paraben-Free Yes
Container Type Bottle

Reviews From Real Customers

jbp2002
marie.g
aiswarya.g

20. Philosophy Ultimate Miracle Worker Multi-Rejuvenating Nighttime Serum-In-Cream 1.7oz / 50ml

Philosophy Ultimate Miracle Worker Multi-Rejuvenating Nighttime Serum-In-Cream 1.7oz / 50ml

  • This serum-in-cream form helps provide a youthful glow to your skin
  • The advanced formula helps keep your skin moisturized for a smooth texture
  • Infused with essential ingredients to offer optimal nourishment for a healthy look

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eBay
Walmart
Ulta Beauty
philosophy

Product Details

Specifications

Details
Weight 1.7 oz
Product Form Serum-in-cream
Container Type Jar
Size One size
Suitable Skin Types All

Reviews From Real Customers

Stephany
Radiogirl
Cindy123

Conclusion

The best night serum for 40s should provide the skin with intense hydration, help to reduce the appearance of fine lines and wrinkles, and promote cell turnover to brighten the complexion. Additionally, it should be packed with antioxidants to help protect the skin from environmental damage.

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