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20 Best Liver Supplements For Dogs (2023 Updated)

There are a few different reasons why your veterinarian may recommend giving your dog liver supplements. One reason is if your dog has been diagnosed with liver disease. Liver disease can be caused by a number of different factors, including genetics, infection, cancer, and toxicity.

Liver disease can lead to a build-up of toxins in the body, which can be very dangerous for your dog. Liver supplements can help to detoxify the body and remove these toxins.

Another reason your veterinarian may recommend liver supplements for your dog is if they are an elderly dog. As dogs age, they can start to experience a decline in liver function. This can lead to a number of different health problems, such as fatigue, weakness, and weight loss.

Liver supplements can help to support the liver and improve its function.

There are a number of different liver supplements available for dogs. Your veterinarian can help you to choose the best supplement for your dog based on their individual needs.

20 Best Liver Supplements For Dogs

Product Image Product Name Features Price

Nutramax Denamarin for Large Dogs, 425 mg, Tablets – 30 count

  • L

RX Vitamins Hepato Support Capsules for Liver – 90 count

  • 90 Capsule

Entirely Pets Denosyl for Small Dogs & Cats – 30 count, 90 mg each

  • Joint health supplement
  • Formulated with glucosamine and chondroitin
  • Most complete joint support supplement available

Coco and Luna Milk Thistle for Dogs, Liver Support, Detox, Hepatic Support, Promotes Liver and Kidney Healthy Function for Pets

  • Important information.
  • Safety Information.
  • Ingredients.

Zesty Paws Liver Support Supplement for Dogs – with Milk Thistle Extract, Turmeric Curcumin, Cranberry Choline – Natural

  • Important information
  • Safety Information
  • Ingredients

SAMeLQ Liver Support for Dogs Cats 225 mg (60 Chewable Tablets)

  • 60 Ct

Herbsmith Milk Thistle Herbal Supplement for Dogs and Cats

  • 150 g

ProHepatic Liver Support Chewable Tablets for Medium Dogs (30 Count)

  • ProHepatic is a potent antioxidant formulation that provides liver function support and protection.
  • Can be given with food.

Vet Classics Liver Support Soft Chews for Dogs & Cats 60 ct

  • Synergistic blend of enzymes, herbs, vitamins, prebiotic, and probiotics combined with antioxidants.
  • Helps to eliminate toxins, strengthen immunity, and stimulate healthy liver functions.

Coco and Luna Liver Support for Dogs and Cats – Milk Thistle Powder 4oz

  • Liver Support – Our advanced formula supports healthy waste elimination, promotes normal hepatic functions and liver health in dogs and cats.

VetriScience Vetri Liver Canine Bite Sized Dog Chews – 60 count, 11.22 oz pouch

  • Contains 15 unique ingredients to support liver health and normal detoxification function
  • Supports Phase 1 and Phase 2 liver detoxification pathways

Pet Wellbeing Milk Thistle for Dogs, 2 oz

  • 2 oz

Vet Classics Liver Support Chew Tabs for Dogs & Cats 60 ct

  • Boost Liver and Overall Health with VetResources Liver Support Tablets
  • Liver disease is a common pet problem with a wide range of effects

Nutri Vet Multi-Vite, for Dogs, Liver Chewables – 60 chewables

  • Vitamin A is essential for normal skin and mucous membrane health, and helps maintain resistance to infections.
  • Vitamin D facilitates proper absorption of calcium and phosphorus from the intestinal tract.
Nutramax Denamarin for Large Dogs, 425 mg, Tablets – 30 count
  • L
RX Vitamins Hepato Support Capsules for Liver – 90 count
  • 90 Capsule
Entirely Pets Denosyl for Small Dogs & Cats – 30 count, 90 mg each
  • Joint health supplement
  • Formulated with glucosamine and chondroitin
  • Most complete joint support supplement available
Coco and Luna Milk Thistle for Dogs, Liver Support, Detox, Hepatic Support, Promotes Liver and Kidney Healthy Function for Pets
  • Important information.
  • Safety Information.
  • Ingredients.
Zesty Paws Liver Support Supplement for Dogs – with Milk Thistle Extract, Turmeric Curcumin, Cranberry Choline – Natural
  • Important information
  • Safety Information
  • Ingredients
SAMeLQ Liver Support for Dogs Cats 225 mg (60 Chewable Tablets)
  • 60 Ct
Herbsmith Milk Thistle Herbal Supplement for Dogs and Cats
  • 150 g
ProHepatic Liver Support Chewable Tablets for Medium Dogs (30 Count)
  • ProHepatic is a potent antioxidant formulation that provides liver function support and protection.
  • Can be given with food.
Vet Classics Liver Support Soft Chews for Dogs & Cats 60 ct
  • Synergistic blend of enzymes, herbs, vitamins, prebiotic, and probiotics combined with antioxidants.
  • Helps to eliminate toxins, strengthen immunity, and stimulate healthy liver functions.
Coco and Luna Liver Support for Dogs and Cats – Milk Thistle Powder 4oz
  • Liver Support – Our advanced formula supports healthy waste elimination, promotes normal hepatic functions and liver health in dogs and cats.
VetriScience Vetri Liver Canine Bite Sized Dog Chews – 60 count, 11.22 oz pouch
  • Contains 15 unique ingredients to support liver health and normal detoxification function
  • Supports Phase 1 and Phase 2 liver detoxification pathways
Pet Wellbeing Milk Thistle for Dogs, 2 oz
  • 2 oz
Vet Classics Liver Support Chew Tabs for Dogs & Cats 60 ct
  • Boost Liver and Overall Health with VetResources Liver Support Tablets
  • Liver disease is a common pet problem with a wide range of effects
Nutri Vet Multi-Vite, for Dogs, Liver Chewables – 60 chewables
  • Vitamin A is essential for normal skin and mucous membrane health, and helps maintain resistance to infections.
  • Vitamin D facilitates proper absorption of calcium and phosphorus from the intestinal tract.

1. Nutramax Denamarin for Large Dogs, 425 mg, Tablets – 30 count

Nutramax Denamarin for Large Dogs, 425 mg, Tablets - 30 count

  • L

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Amazon.com
Chewy.com
Allivet Pet Pharmacy
VetRxDirect a Pet Pharmacy

Product Details

Specifications

Details
Weight 4.1 oz

Reviews From Real Customers

tntsang
Zoey
Mikeysmom

2. RX Vitamins Hepato Support Capsules for Liver – 90 count

RX Vitamins Hepato Support Capsules for Liver - 90 count

  • 90 Capsule

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Amazon.com – Seller
eBay
Chewy.com
PetMeds

Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Item Package Dimensions L x W x H 3.8 x 2.25 x 2.25 inches
Item Dimensions LxWxH 4 x 3 x 3 inches
Target Audience Keyword House-cats
Included Components Hepato Support for Pets (90 Capsules)

Reviews From Real Customers

OzzysMom
Peggy

3. Entirely Pets Denosyl for Small Dogs & Cats – 30 count, 90 mg each

Entirely Pets Denosyl for Small Dogs & Cats - 30 count, 90 mg each

  • Joint health supplement
  • Formulated with glucosamine and chondroitin
  • Most complete joint support supplement available

Check Latest Price

Sold By Price
Amazon.com
eBay
Walmart – Walmart Pet RX
Chewy.com

Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Product Dimensions 5 x 5 x 5 inches; 0.8 Ounces
Item Package Dimensions L x W x H 5.63 x 3.51 x 1.34 inches
Item Dimensions LxWxH 5 x 5 x 5 inches
Target Audience Keyword Dogs, ( reptiles | amphibians )
Directions Use as directed on package.
Breed Recommendation Small Breeds
Specific Uses for Product Urinary

Reviews From Real Customers

HuskyGirl
Gail
Tbone

4. Coco and Luna Milk Thistle for Dogs, Liver Support, Detox, Hepatic Support, Promotes Liver and Kidney Healthy Function for Pets

Coco and Luna Milk Thistle for Dogs, Liver Support, Detox, Hepatic Support, Promotes Liver and Kidney Healthy Function for Pets

  • Important information.
  • Safety Information.
  • Ingredients.
  • Up to 25 lbs. give 1 tablet; from 26-50 lbs. give 2 tablets; from 51-74 lbs. give 3 tablets; over 75 lbs. give 4 tablets.

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Amazon.com – Seller
eBay
Walmart – Vita Pet Life LLC
Chewy.com

Product Details

Specifications

Details
Package Dimensions 5.2 x 2.36 x 2.32 inches; 4 Ounces
Country of Origin USA
Item Package Dimensions L x W x H 5.2 x 2.36 x 2.32 inches
Target Audience Keyword Dogs

Reviews From Real Customers

RichB
JayKay
Sawyersmom

5. Zesty Paws Liver Support Supplement for Dogs – with Milk Thistle Extract, Turmeric Curcumin, Cranberry Choline – Natural

Zesty Paws Liver Support Supplement for Dogs - with Milk Thistle Extract, Turmeric Curcumin, Cranberry Choline - Natural

  • Important information
  • Safety Information
  • Ingredients

Check Latest Price

Sold By Price
Amazon
eBay – rapidlinervitamins101
Chewy.com

Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Product Dimensions 3.5 x 3.5 x 4 inches; 15.52 Ounces
Country of Origin USA
Item Package Dimensions L x W x H 4.09 x 3.74 x 3.7 inches
Item Dimensions LxWxH 3.5 x 3.5 x 4 inches

Reviews From Real Customers

AllAboutAlan
zestypaws.com
Bean

6. SAMeLQ Liver Support for Dogs Cats 225 mg (60 Chewable Tablets)

SAMeLQ Liver Support for Dogs Cats 225 mg (60 Chewable Tablets)

  • 60 Ct

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Amazon
Allivet Pet Pharmacy
Heartland Veterinary Supply and Pharmacy

Product Details

Reviews From Real Customers

Kim M
Martha G
Candie

7. Herbsmith Milk Thistle Herbal Supplement for Dogs and Cats

Herbsmith Milk Thistle Herbal Supplement for Dogs and Cats

  • 150 g

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Amazon
Herbsmith
Chewy.com
HealthyPets.com

Product Details

Specifications

Details
NASC Certified Yes
Product Form Powder

Reviews From Real Customers

Zekee
Skymom
twentyeightfeet

8. Dr. Mercola Liver & Kidney Support for Cats & Dogs 1.7 oz

Dr. Mercola Liver & Kidney Support for Cats & Dogs 1.7 oz

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Amazon
PureFormulas.com
Natural Healthy Concepts
Professional Supplement Center

Product Details

Specifications

Details
Made in USA

Reviews From Real Customers

Anakin
RooRookittys2
kittyl

9. ProHepatic Liver Support Chewable Tablets for Medium Dogs (30 Count)

ProHepatic Liver Support Chewable Tablets for Medium Dogs (30 Count)

  • ProHepatic is a potent antioxidant formulation that provides liver function support and protection.
  • Can be given with food.
  • Easier to use than SAMe (very small chewable tablet).

Check Latest Price

Sold By Price
Amazon
Valley Vet Supply
Allivet Pet Pharmacy
HealthWarehouse.com

Product Details

Reviews From Real Customers

Kerstin D
Kathy T
JACKIE J

10. Liver-Love Kit – Best Liver Support for Dogs by Pet Wellbeing 7.53 oz

Liver-Love Kit - Best Liver Support for Dogs by Pet Wellbeing 7.53 oz

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Amazon
PetWellbeing

Product Details

Reviews From Real Customers

Kim R.

11. Vet Classics Liver Support Soft Chews for Dogs & Cats 60 ct

Vet Classics Liver Support Soft Chews for Dogs & Cats 60 ct

  • Synergistic blend of enzymes, herbs, vitamins, prebiotic, and probiotics combined with antioxidants.
  • Helps to eliminate toxins, strengthen immunity, and stimulate healthy liver functions.
  • For use in dogs and cats over the age of 12 weeks.

Check Latest Price

Sold By Price
Amazon
eBay – pethealthmarket
Chewy.com
Only Natural Pet

Product Details

Specifications

Details
Breed Size Large Breeds, Medium Breeds, Small Breeds
Product Form Soft Chew

Reviews From Real Customers

Kaeli
Myshelty
LouieLaylaMom

12. Coco and Luna Liver Support for Dogs and Cats – Milk Thistle Powder 4oz

Coco and Luna Liver Support for Dogs and Cats - Milk Thistle Powder 4oz

  • Liver Support – Our advanced formula supports healthy waste elimination, promotes normal hepatic functions and liver health in dogs and cats.
  • Easy to Serve Powder – Our formula has the best natural ingredients, adjusted for cats and dogs in an easy to serve format.
  • Made in the USA – All our products are made in the USA and are veterinarian approved as well as hypoallergenic.

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Amazon
Walmart – Vita Pet Life LLC
Chewy.com

Product Details

Specifications

Details
Shop Conscious Non-GMO
Special Diet Non-GMO
Product Form Powder

13. VetriScience Vetri Liver Canine Bite Sized Dog Chews – 60 count, 11.22 oz pouch

VetriScience Vetri Liver Canine Bite Sized Dog Chews - 60 count, 11.22 oz pouch

  • Contains 15 unique ingredients to support liver health and normal detoxification function
  • Supports Phase 1 and Phase 2 liver detoxification pathways
  • Antioxidant protection

Check Latest Price

Sold By Price
Amazon
Chewy.com
PetCareRx
Holistic Pet Info

Product Details

Specifications

Details
Contains Does Not Contain Any of the 8 Major Allergens
Intended Pet Type Dog
State of Readiness Ready to Eat
Form Loose
Pet Lifestage All Ages

Reviews From Real Customers

Stitchy
NT33647

14. Pet Wellbeing Milk Thistle for Dogs, 2 oz

Pet Wellbeing Milk Thistle for Dogs, 2 oz

  • 2 oz

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Amazon
eBay
Chewy.com
PetWellbeing

Product Details

Specifications

Details
Primary Flavor Bacon
Primary Brand Pet Wellbeing
Grain Free Yes
Live Food No
Length 1.5 IN

Reviews From Real Customers

petwellbeing.ca
Barb M.
Svetlana F.

15. Vet Classics Liver Support Chew Tabs for Dogs & Cats 60 ct

Vet Classics Liver Support Chew Tabs for Dogs & Cats 60 ct

  • Boost Liver and Overall Health with VetResources Liver Support Tablets
  • Liver disease is a common pet problem with a wide range of effects
  • Milk thistle promotes cell regeneration and also has anti-inflammatory effects
  • Dandelion root stimulates circulation in the liver and the production of bile

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Amazon
eBay
Chewy.com
Only Natural Pet

Product Details

Specifications

Details
Breed Size Small Breeds, Medium Breeds, Large Breeds
Product Form Chewable Tablet

Reviews From Real Customers

AJLI

16. ThorneVet Hepagen – Liver Support for Dogs & Cats – 90 Chews

ThorneVet Hepagen - Liver Support for Dogs & Cats - 90 Chews

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Amazon
Holistic Pet Info

Product Details

Reviews From Real Customers

Lauren H.
Lora J.
Gabe's mom

17. Nutri Vet Multi-Vite, for Dogs, Liver Chewables – 60 chewables

Nutri Vet Multi-Vite, for Dogs, Liver Chewables - 60 chewables

  • Vitamin A is essential for normal skin and mucous membrane health, and helps maintain resistance to infections.
  • Vitamin D facilitates proper absorption of calcium and phosphorus from the intestinal tract.
  • Vitamin C supports joint, cardiovascular, cognitive, visual and immune system health.
  • Riboflavin (Vitamin B2) promotes the release of energy from carbohydrates, fats and proteins, and maintains the integrity of red blood cells.

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Chewy.com
Tractor Supply Company
Fred Meyer

Product Details

Specifications

Details
Units in Package 60
Directions Suggested Use: One (1) chewable per 20 lbs. of body weight daily. Continue as needed.
Ingredients Liver Meal, Dicalcium Phosphate, Sucrose, Ascorbic Acid, Stearic Acid, Cellulose, Safflower Oil, Corn Starch, Potassium Chloride, Magnesium Silicate, Niacinamide, Magnesium Oxide, Hydrolyzed Vegetable Protein, DL-Alpha Tocopheryl Acetate, Ferrous Fumarate, Magnesium Stearate, Vitamin A Acetate, Zinc Oxide, Riboflavin, Thiamine Mononitrate, Manganese Sulfate, Vitamin D3 Supplement, Copper Sulfate Monohydrate, Pyridoxine Hydrochloride, Potassium Iodide, Vitamin B12 Supplement.
Warnings Do not use if product appears to be tampered with. Store product in cool, dry place. Avoid temperatures above 86 degrees F Keep out of reach of children and pets to avoid unintended consumption. This product is intended for intermittent or supplemental feeding only.

Reviews From Real Customers

Abigail
Noodle
2Pups

18. Prana Pets LFS2 Dogs Cats Liver Function Support Supplement 2 oz Dropp

Prana Pets LFS2 Dogs Cats Liver Function Support Supplement 2 oz Dropp

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eBay – purchasedirect
Chewy.com

Product Details

Specifications

Details
Breed Size Medium Breeds, Small Breeds, Large Breeds
Product Form Liquid

Reviews From Real Customers

Connaught C.
Claire H.
Tanith S.

19. Adored Beast Liver Tonic for Dogs and Cats

Adored Beast Liver Tonic for Dogs and Cats

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NaturalPetWarehouse.com
Fetched-Up
Happy Hounds Pet Supply
Aleyr Pet Store

Product Details

Specifications

Details
precautions Refrigerate after opening
product form Liquide

Reviews From Real Customers

Dorothy H.
Audra C.
Steven K.

20. Liver Support Soft Chew 60 Count for Pets by Vet Classics

Liver Support Soft Chew 60 Count for Pets by Vet Classics

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Vet Approved RX

Product Details

Conclusion

Including the specific condition being treated, the severity of the condition, the age and health of the dog, and other factors. Liver supplements may be helpful for some dogs with liver disease, but they are not a cure and may not be appropriate for all dogs.

Talk to your veterinarian about whether liver supplements are right for your dog.

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