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11 Best Heartworm Protection For Dogs (2023 Updated)

Heartworm disease is a potentially fatal condition caused by parasitic worms living in the heart and pulmonary arteries of infected dogs. Heartworm disease is most commonly transmitted to dogs by mosquito bites, and it can be fatal if left untreated.

Heartworm protection for dogs is therefore essential to keeping your dog healthy and safe from this potentially deadly disease. There are a number of products available that can protect your dog from heartworm, and it is important to talk to your veterinarian about the best option for your dog.

11 Best Heartworm Protection For Dogs

Product Image Product Name Features Price

Nemex-2, 2 oz.

  • Safe, palatable and convenient
  • 4.54 mg pyrantel pamoate per ml
  • Controls large roundworms and hookworms in dogs

Revolution Plus for Cats 5.6-11 lbs 6 Doses

  • One dose protects against 6 common parasites: Flea, Ticks, Ear Mites, Roundworms, Hookworms and Heartworms.
  • Safe for cats and kitten as young as 8 weeks of age, weighing 2.8lbs or greater.

Panacur C Canine Dewormer (2 Gram)

  • 2 gram packet 40 lb 4 gram packet 50 lb 1 gram packet.
  • 4 gram packet 60 lb 2 gram packet.
  • 4 gram packet 80 lb Two 4 gram packets Over 80 lb Use combinations to obtain recommended daily dose.

Interceptor Plus Chewable for Dogs, Green, 8.1-25 lbs 6 Doses

  • Protects your dog against heartworm, roundworms, hookworms, whipworms, and tapeworms
  • Get broad-spectrum protection for peace of mind

Bravecto Topical Solution for Dogs – 44-88 lbs (2 Tubes)

  • 112.5 mg fluralaner; 9.9-22 lbs.
  • 25 mg fluralaner; 22-44 lbs.
  • 500 mg fluralaner; 44-88 lbs.

Revolution Plus for Cats, Green 11.1-22 lbs, 3 Doses

  • One dose protects against 6 common parasites: Flea, Ticks, Ear Mites, Roundworms, Hookworms and Heartworms.
  • Safe for cats and kitten as young as 8 weeks of age, weighing 2.8lbs or greater.

Advocate Small Dog Upto 4kg 3 Pack

  • Small Advocate provides dogs up to 4kg treatment and prevention of fleas and reduces the incidence of flea allergy dermatitis.

Bravecto for Dogs 22-44 lbs 1 Tablet

  • Simple to give chewable tablet.
  • Safe in breeding, pregnant and lactating dogs.

Revolution for Cats – 15.1-22 lbs (3 Doses)

  • Heartworm preventive for cats or kittens
  • Medication also can be used to treat and control roundworms and hookworms in cats

Advantage Multi for Dogs 9.1-20 lbs

  • Prescription topical protects your dog from heartworm disease
  • Treats circulating microfilariae
  • Kills adult fleas
Nemex-2, 2 oz.
  • Safe, palatable and convenient
  • 4.54 mg pyrantel pamoate per ml
  • Controls large roundworms and hookworms in dogs
Revolution Plus for Cats 5.6-11 lbs 6 Doses
  • One dose protects against 6 common parasites: Flea, Ticks, Ear Mites, Roundworms, Hookworms and Heartworms.
  • Safe for cats and kitten as young as 8 weeks of age, weighing 2.8lbs or greater.
Panacur C Canine Dewormer (2 Gram)
  • 2 gram packet 40 lb 4 gram packet 50 lb 1 gram packet.
  • 4 gram packet 60 lb 2 gram packet.
  • 4 gram packet 80 lb Two 4 gram packets Over 80 lb Use combinations to obtain recommended daily dose.
Interceptor Plus Chewable for Dogs, Green, 8.1-25 lbs 6 Doses
  • Protects your dog against heartworm, roundworms, hookworms, whipworms, and tapeworms
  • Get broad-spectrum protection for peace of mind
Bravecto Topical Solution for Dogs – 44-88 lbs (2 Tubes)
  • 112.5 mg fluralaner; 9.9-22 lbs.
  • 25 mg fluralaner; 22-44 lbs.
  • 500 mg fluralaner; 44-88 lbs.
Revolution Plus for Cats, Green 11.1-22 lbs, 3 Doses
  • One dose protects against 6 common parasites: Flea, Ticks, Ear Mites, Roundworms, Hookworms and Heartworms.
  • Safe for cats and kitten as young as 8 weeks of age, weighing 2.8lbs or greater.
Advocate Small Dog Upto 4kg 3 Pack
  • Small Advocate provides dogs up to 4kg treatment and prevention of fleas and reduces the incidence of flea allergy dermatitis.
Bravecto for Dogs 22-44 lbs 1 Tablet
  • Simple to give chewable tablet.
  • Safe in breeding, pregnant and lactating dogs.
Revolution for Cats – 15.1-22 lbs (3 Doses)
  • Heartworm preventive for cats or kittens
  • Medication also can be used to treat and control roundworms and hookworms in cats
Advantage Multi for Dogs 9.1-20 lbs
  • Prescription topical protects your dog from heartworm disease
  • Treats circulating microfilariae
  • Kills adult fleas

1. Nemex-2, 2 oz.

Nemex-2, 2 oz.

  • Safe, palatable and convenient
  • 4.54 mg pyrantel pamoate per ml
  • Controls large roundworms and hookworms in dogs
  • Safe for puppies

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eBay
Walmart – Walmart Pet RX
Tractor Supply Company

Product Details

Specifications

Details
Country of Origin Made in USA
Animal Type Dog
Dewormer Features Safe for Lactating Animals
Manufacturer Brand Zoetis
Packaged Height 3.25 in
Packaged Length 1.75 in
Packaged Weight 0.15 lb
Packaged Width 1.75 in
Product Form Liquid
Product Width 1.9 in
Targeted Parasites Roundworms, Hookworms

Reviews From Real Customers

Jenn D FL
Mustang Meowy
Jacqueline G.

2. Revolution Plus for Cats 5.6-11 lbs 6 Doses

Revolution Plus for Cats 5.6-11 lbs 6 Doses

  • One dose protects against 6 common parasites: Flea, Ticks, Ear Mites, Roundworms, Hookworms and Heartworms.
  • Safe for cats and kitten as young as 8 weeks of age, weighing 2.8lbs or greater.
  • Simple to apply, quick drying, small-volume, monthly topical solution.
  • No separation required after applying.

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Amazon
Walmart – Walmart Pet RX
Revival Animal Health
Allivet Pet Pharmacy

Product Details

Specifications

Details
For Use With Cats
Administration Form Topical
Breed Size Medium Breeds
Product Form Solution
Strength 30 mg Selamectin and 5 mg Sarolaner
Drug Type Parasiticide

3. Panacur C Canine Dewormer (2 Gram)

Panacur C Canine Dewormer (2 Gram)

  • 2 gram packet 40 lb 4 gram packet 50 lb 1 gram packet.
  • 4 gram packet 60 lb 2 gram packet.
  • 4 gram packet 80 lb Two 4 gram packets Over 80 lb Use combinations to obtain recommended daily dose.

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Amazon
PetCareRx
Allivet Pet Pharmacy
Chewy.com

Product Details

Specifications

Details
Dimensions 19.6 x 12.1 x 5.2 inches
Breed Size Small Breeds, Medium Breeds
Product Form Powder
Drug Type Parasiticide

Reviews From Real Customers

Sharilee3
Sylvia
dontneedanickname

4. Interceptor Plus Chewable for Dogs, Green, 8.1-25 lbs 6 Doses

Interceptor Plus Chewable for Dogs, Green, 8.1-25 lbs 6 Doses

  • Protects your dog against heartworm, roundworms, hookworms, whipworms, and tapeworms
  • Get broad-spectrum protection for peace of mind
  • Easy-to-give chewables are flavored with real chicken and taste like treats

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Allivet Pet Pharmacy
Valley Vet Supply
PetMeds
petvm.com

Product Details

Specifications

Details
For Use With Dogs
Administration Form Oral
Breed Size Extra Small Breeds, Small Breeds
Product Form Chew
Strength 5.75 mg Milbemycin Oxime and 57 mg Praziquantel
Drug Type Parasiticide

Reviews From Real Customers

Oceanna Cruise
kensch888

5. Bravecto Topical Solution for Dogs – 44-88 lbs (2 Tubes)

Bravecto Topical Solution for Dogs - 44-88 lbs (2 Tubes)

  • 112.5 mg fluralaner; 9.9-22 lbs.
  • 25 mg fluralaner; 22-44 lbs.
  • 500 mg fluralaner; 44-88 lbs.
  • 1000 mg fluralaner; 88-123 lbs.
  • 1400 mg fluralaner.

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Walmart – Walmart Pet RX
Chewy.com
Allivet Pet Pharmacy
PetMeds

Product Details

Specifications

Details
For Use With Dogs 44-88 lbs. Do not use on dogs under 4.4 lbs
Administration Form Topical
Breed Size Medium Breeds, Large Breeds
Product Form Solution
Strength 1000 mg Fluralaner
Drug Type Parasiticide

Reviews From Real Customers

Britty
DaveL

6. Revolution Plus for Cats, Green 11.1-22 lbs, 3 Doses

Revolution Plus for Cats, Green 11.1-22 lbs, 3 Doses

  • One dose protects against 6 common parasites: Flea, Ticks, Ear Mites, Roundworms, Hookworms and Heartworms.
  • Safe for cats and kitten as young as 8 weeks of age, weighing 2.8lbs or greater.
  • Simple to apply, quick drying, small-volume, monthly topical solution.
  • No separation required after applying.

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Sold By Price
Walmart – Walmart Pet RX
Allivet Pet Pharmacy
PetCareRx
VetRxDirect a Pet Pharmacy

Product Details

Specifications

Details
Primary Brand Revolution Plus

Reviews From Real Customers

KillerQueenKitti
Eliza

7. Advocate Small Dog Upto 4kg 3 Pack

Advocate Small Dog Upto 4kg 3 Pack

  • Small Advocate provides dogs up to 4kg treatment and prevention of fleas and reduces the incidence of flea allergy dermatitis.
  • Larval flea stages are killed in the surrounding of Advocate treated pets and prevents heartworm infection (Dirofilaria immitis).
  • Product Details.

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Bonanza – Banyer

Product Details

Reviews From Real Customers

Andrew W.
Nyree W.

8. Bravecto for Dogs 22-44 lbs 1 Tablet

Bravecto for Dogs 22-44 lbs 1 Tablet

  • Simple to give chewable tablet.
  • Safe in breeding, pregnant and lactating dogs.

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EntirelyPets Pharmacy
PetMeds

Product Details

Reviews From Real Customers

Ozzy

9. Revolution for Cats – 15.1-22 lbs (3 Doses)

Revolution for Cats - 15.1-22 lbs (3 Doses)

  • Heartworm preventive for cats or kittens
  • Medication also can be used to treat and control roundworms and hookworms in cats
  • Also delivers flea control and prevention

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Allivet Pet Pharmacy
PetCareRx
Chewy.com
Petco.com

Product Details

Specifications

Details
Primary Brand Revolution

Reviews From Real Customers

DWESFam
zkid
Sandi

10. Advantage Multi for Dogs 9.1-20 lbs

Advantage Multi for Dogs 9.1-20 lbs

  • Prescription topical protects your dog from heartworm disease
  • Treats circulating microfilariae
  • Kills adult fleas

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Walmart
Chewy.com
Allivet Pet Pharmacy
Valley Vet Supply

Product Details

Specifications

Details
For Use With Dogs
Administration Form Topical
Breed Size Small Breeds
Product Form Solution
Strength 100 mg Imidacloprid and 25 mg Moxidectin
Drug Type Parasiticide

Reviews From Real Customers

Mary B
Rhouston52
Coffeehound

11. Simparica Trio for Dogs 5.6-11 lbs, 6 Chewables

Simparica Trio for Dogs 5.6-11 lbs, 6 Chewables

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Allivet Pet Pharmacy
Valley Vet Supply
PetCareRx
petvm.com

Product Details

Reviews From Real Customers

DaisysMom
LexYve93
Heather B.

Conclusion

The best way to protect your dog from heartworm is to use a monthly preventative. There are many different types of preventatives available, so speak with your veterinarian to find the best option for your dog.

It is important to give the preventative to your dog every month, even if they do not go outside often or live in an area with a low risk of heartworm. This is because heartworm can still be transmitted indoors and from other animals, so it is important to be vigilant in your protection.

If you miss a dose or are late in giving the preventative, be sure to contact your veterinarian as soon as possible so they can advise you on the best course of action.

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