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20 Best Heartworm And Flea Prevention For Dogs (2022 Updated)

Heartworm and flea prevention for dogs is a medication that is given to dogs to prevent them from getting heartworms and fleas.

20 Best Heartworm And Flea Prevention For Dogs

Product Image Product Name Features Price

Heartgard Tablets 26-50 lbs, 6 Month Supply

  • 26-50 lbs

Heartgard Plus for Dogs – 26-50 lbs (1 Chew)

  • 26-50 lbs

Intervet Safe-Guard Canine Dewormer – 3 pack, 1 g packets

  • Mix with food
  • Comes in three day convenient doses
  • Safe and effective

Novartis Sentinel Flavor Tabs for Dogs, 51-100 lbs – 6 pack

  • 51-100 lbs

Interceptor Plus Chewables for Dogs 2-8 lbs, 6 Month Supply

  • 50-100 lbs

Sentinel Flavor Tabs for Dogs 51-100 lbs, 6 Month Supply

  • White

Iverhart Plus for Dogs 1-25 lbs, Blue, 6 Pack

  • 1-25 lbs

Iverhart Plus Flavored Chewables for Dogs 51-100 lbs, 6 Month Supply

  • 51-100 lbs, 6 Month

Interceptor Green, Dogs 11-25lbs / Cats 1.5-6lbs. 12 Month Supply

  • 1.5-8 lbs / 11-25 lbs

Sentinel Spectrum 2-8 lbs, 6 Month Supply

  • 2-8 lbs

Revolution for Dogs 0-5 lbs 6 Doses by Zoetis

  • Eliminates fleas treatment and prevention
  • Tick Control
  • Dog Flea Tablets

Sentinel Spectrum for Dogs – 50-100 lbs – 6 Count

  • 50-100 lbs

Revolution for Dogs, 85.1-130 lbs (3 Doses)

  • 85.1-130 lbs., 6 Month

Sentinel Spectrum 50.1-100 lbs, 6 Month Supply

  • 50.1-100 lbs

Simparica Trio 11.1-22 lbs. Dogs, 6 Month Supply

  • 11.1-22 lbs

MilbeGuard for Dogs 26-50 lbs & Cats 6.1-12 lbs – 6 Flavored Tablets

  • 1-Pack

Interceptor Brown, Dogs 2-10 lbs. 12 Month Supply

  • Interceptor is contraindicated in animals with a history of an allergic reaction to milbemycin. Keep out of reach of children.
Heartgard Tablets 26-50 lbs, 6 Month Supply
  • 26-50 lbs
Heartgard Plus for Dogs – 26-50 lbs (1 Chew)
  • 26-50 lbs
Intervet Safe-Guard Canine Dewormer – 3 pack, 1 g packets
  • Mix with food
  • Comes in three day convenient doses
  • Safe and effective
Novartis Sentinel Flavor Tabs for Dogs, 51-100 lbs – 6 pack
  • 51-100 lbs
Interceptor Plus Chewables for Dogs 2-8 lbs, 6 Month Supply
  • 50-100 lbs
Sentinel Flavor Tabs for Dogs 51-100 lbs, 6 Month Supply
  • White
Iverhart Plus for Dogs 1-25 lbs, Blue, 6 Pack
  • 1-25 lbs
Iverhart Plus Flavored Chewables for Dogs 51-100 lbs, 6 Month Supply
  • 51-100 lbs, 6 Month
Interceptor Green, Dogs 11-25lbs / Cats 1.5-6lbs. 12 Month Supply
  • 1.5-8 lbs / 11-25 lbs
Sentinel Spectrum 2-8 lbs, 6 Month Supply
  • 2-8 lbs
Revolution for Dogs 0-5 lbs 6 Doses by Zoetis
  • Eliminates fleas treatment and prevention
  • Tick Control
  • Dog Flea Tablets
Sentinel Spectrum for Dogs – 50-100 lbs – 6 Count
  • 50-100 lbs
Revolution for Dogs, 85.1-130 lbs (3 Doses)
  • 85.1-130 lbs., 6 Month
Sentinel Spectrum 50.1-100 lbs, 6 Month Supply
  • 50.1-100 lbs
Simparica Trio 11.1-22 lbs. Dogs, 6 Month Supply
  • 11.1-22 lbs
MilbeGuard for Dogs 26-50 lbs & Cats 6.1-12 lbs – 6 Flavored Tablets
  • 1-Pack
Interceptor Brown, Dogs 2-10 lbs. 12 Month Supply
  • Interceptor is contraindicated in animals with a history of an allergic reaction to milbemycin. Keep out of reach of children.

1. Heartgard Tablets 26-50 lbs, 6 Month Supply

Heartgard Tablets 26-50 lbs, 6 Month Supply

  • 26-50 lbs

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Product Details

Specifications

Details
For Use With Dogs – 6 weeks or older
Administration Form Oral
Breed Size Medium Breeds
Product Form Chew
Strength 136 mcg Ivermectin and 114 mg Pyrantel

2. Tri-Heart Plus Chewable Tablets for Dogs, 51-100 lbs

Tri-Heart Plus Chewable Tablets for Dogs, 51-100 lbs

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3. Heartgard Plus for Dogs – 26-50 lbs (1 Chew)

Heartgard Plus for Dogs - 26-50 lbs (1 Chew)

  • 26-50 lbs

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4. Intervet Safe-Guard Canine Dewormer – 3 pack, 1 g packets

Intervet Safe-Guard Canine Dewormer - 3 pack, 1 g packets

  • Mix with food
  • Comes in three day convenient doses
  • Safe and effective
  • Treats and controls tapeworms, roundworms, hookworms, and whipworms
  • No prescription needed

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Specifications

Details
Units in Package 3
Unit Size 1 g packets
Indications For the treatment and control of roundworms (toxocara canis, toxascaris leonina), hookworms (ancylostomia canium, uncinaria stenocephala), whipworms (trichuris vulpis), and tapeworms (taenia pisiformis).
Directions Consult your veterinarian for assistance in the diagnosis, treatment, and control of parastism. The daily dose is mg/kg (22.7 mg/lb) of body weight. Please refer to the following dosing table for help in finding the right dose for your dog. Dosing Table: 10 pounds: 1 gram, 20 pounds: 2 grams, 30 pounds: 1 gram, 40 pounds: 4 gram, 50 pounds: 1 gram plus 4 gram, 60 pound: 2 gram plus 4 grams, 80 pounds: two 4 gram, over 80 pounds: use combinations to obtain recommended daily dose. Packet size is the daily dose. the dog must be treated wit this dose 3 days in a row. You should weigh your dog to make sure you are using the right size and number of packets. If your dog’s weight is in – between the suggested dosing sizes. It is safe to use the next higher size. For example, a 15-pound dog should be treated with the 2-gram packet. Give to your dog by mixing the daily dose with a small amount of the usual food. Make sure your dog eats all of the medicated food. You may need to moisten dry dog food to aid mixing. Repeat the daily dose for three days in row. Deworming schedules may vary depending on the climate where you live and the activity of our dog. The following schedule should be used as general guidance. Newly weaned pups (6 to 8 weeks of age). should be dewormed at 6, 8, 10 and 12 weeks of Age. Treat the dam at the same time as the puppies, dogs over six months of age should be dewormed. at least twice each year. Each deworming requires 3 daily treatments. Storage: Store at controlled room temperature.
Warnings Keep this and all medications out of the reach of children. In US clinical studies 3 of 240 dogs (about 1% of the treated dogs) had vomiting associated with use of this product. When using this product: Safe-Guard Canine is safe for use in puppies 6 weeks or older and adult dogs, including pregnant bitches. Do not deworm a dog or puppy that is sick. Consult your veterinarian for diagnosis of the illness.

Reviews From Real Customers

Neemo
BZOO23

5. Novartis Sentinel Flavor Tabs for Dogs, 51-100 lbs – 6 pack

Novartis Sentinel Flavor Tabs for Dogs, 51-100 lbs - 6 pack

  • 51-100 lbs

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PetCareRx

Product Details

Specifications

Details
For Use With Dogs
Administration Form Oral
Breed Size Medium Breeds, Large Breeds
Product Form Tablet
Strength 23 mg Milbemycin Oxime and 460 mg Lufenuron

6. Interceptor Plus Chewables for Dogs 2-8 lbs, 6 Month Supply

Interceptor Plus Chewables for Dogs 2-8 lbs, 6 Month Supply

  • 50-100 lbs

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Product Details

Specifications

Details
Primary Brand Interceptor Plus
For Pet Weight Max 8 LBS
For Pet Weight Min 2 LBS

7. Sentinel Flavor Tabs for Dogs 51-100 lbs, 6 Month Supply

Sentinel Flavor Tabs for Dogs 51-100 lbs, 6 Month Supply

  • White

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Valley Vet Supply
VetRxDirect a Pet Pharmacy
Revival Animal Health

Product Details

Specifications

Details
Weight and Color 51-100 lbs White

8. Trifexis 20.1-40 lbs for Dogs, 6 Chewable Tablets by EntirelyPets Pharmacy

Trifexis 20.1-40 lbs for Dogs, 6 Chewable Tablets by EntirelyPets Pharmacy

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Specifications

Details
For Use With Dogs
Administration Form Oral
Breed Size Small Breeds, Medium Breeds
Product Form Chewable Tablet
Strength 560 mg Spinosad and 9.3 mg Milbemycin Oxime

9. Iverhart Plus for Dogs 1-25 lbs, Blue, 6 Pack

Iverhart Plus for Dogs 1-25 lbs, Blue, 6 Pack

  • 1-25 lbs

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10. Iverhart Plus Flavored Chewables for Dogs 51-100 lbs, 6 Month Supply

Iverhart Plus Flavored Chewables for Dogs 51-100 lbs, 6 Month Supply

  • 51-100 lbs, 6 Month

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Reviews From Real Customers

WILLIAM B
Claudia

11. Interceptor Green, Dogs 11-25lbs / Cats 1.5-6lbs. 12 Month Supply

Interceptor Green, Dogs 11-25lbs / Cats 1.5-6lbs. 12 Month Supply

  • 1.5-8 lbs / 11-25 lbs

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12. Tri-Heart Plus Chewable Tablets for Dogs, 26-50 lbs

Tri-Heart Plus Chewable Tablets for Dogs, 26-50 lbs

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13. Sentinel Spectrum 2-8 lbs, 6 Month Supply

Sentinel Spectrum 2-8 lbs, 6 Month Supply

  • 2-8 lbs

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14. Revolution for Dogs 0-5 lbs 6 Doses by Zoetis

Revolution for Dogs 0-5 lbs 6 Doses by Zoetis

  • Eliminates fleas treatment and prevention
  • Tick Control
  • Dog Flea Tablets

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petvm.com

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15. Sentinel Spectrum for Dogs – 50-100 lbs – 6 Count

Sentinel Spectrum for Dogs - 50-100 lbs - 6 Count

  • 50-100 lbs

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petvm.com
Revival Animal Health
EntirelyPets Pharmacy

Product Details

Specifications

Details
For Use With Dogs
Administration Form Oral
Breed Size Medium Breeds, Large Breeds
Product Form Chew
Drug Type Parasiticide

16. Revolution for Dogs, 85.1-130 lbs (3 Doses)

Revolution for Dogs, 85.1-130 lbs (3 Doses)

  • 85.1-130 lbs., 6 Month

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17. Sentinel Spectrum 50.1-100 lbs, 6 Month Supply

Sentinel Spectrum 50.1-100 lbs, 6 Month Supply

  • 50.1-100 lbs

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18. Simparica Trio 11.1-22 lbs. Dogs, 6 Month Supply

Simparica Trio 11.1-22 lbs. Dogs, 6 Month Supply

  • 11.1-22 lbs

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Valley Vet Supply
PetCareRx
Allivet Pet Pharmacy

Product Details

Specifications

Details
For Use With Dogs
Administration Form Oral
Breed Size Small Breeds
Product Form Chewable Tablet
Drug Type Parasiticide

19. MilbeGuard for Dogs 26-50 lbs & Cats 6.1-12 lbs – 6 Flavored Tablets

MilbeGuard for Dogs 26-50 lbs & Cats 6.1-12 lbs - 6 Flavored Tablets

  • 1-Pack

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California Pet Pharmacy

Product Details

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Details
Body Weight MilbeGuard Flavored Tablets

Reviews From Real Customers

Lilli Y
Madeleine
Sharon W

20. Interceptor Brown, Dogs 2-10 lbs. 12 Month Supply

Interceptor Brown, Dogs 2-10 lbs. 12 Month Supply

  • Interceptor is contraindicated in animals with a history of an allergic reaction to milbemycin. Keep out of reach of children.
  • Possible side effects.
  • If you miss giving a dose, give it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Do not double the dose.

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Review Date 7/8/2012

Conclusion

The best way to prevent heartworm and fleas in dogs is to use a combination of monthly heartworm prevention medication and a monthly flea and tick prevention medication.

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