Best Heartworm And Flea Prevention For Dogs (2026 Updated)

Heartgard Chewable Tablet for Dogs, 26-50 lbs, (Green Box), 6 Chewable Tablets (6-Months Protection); Your furry friend must have a current heartworm test result on file with your veterinarian in order to be prescribed heartworm medication.

Please visit your veterinarian to have this test performed annually to protect your four-legged friend. Heartgard Unflavored tablets for dogs is a heartworm preventative that kills heartworms. Given monthly, it comes in a chewable, unflavored tablet that is easily pilled or disguised in food.

Veterinarians recommend Tri-Heart Plus for Dogs 51-100 lbs. for prevention of heartworm disease and for control/treatment of common intestinal parasites. What is Tri-Heart Plus for Dogs 51-100 lbs? This is a highly effective branded generic preventative medication that kills immature heartworms to prevent heartworm disease.

It also works well to control/treat roundworms and hookworms. What are the benefits of Tri-Heart Plus for Dogs 26-50 lbs? Broad-spectrum medication that protects your dog against immature heartworms and adult hookworms/roundworms.

Requires oral administration only once a month. Palatable and easy to give to most dogs. Formulated for: This size of Tri-Heart Plus can be given safely to dogs over 6 weeks of age weighing 51-100 lbs.

It is also considered safe for pregnant/ breeding females when supervised by your veterinarian. How is this medication given? Tablets should be given by mouth and should be chewed or mixed with a small amount of food.

Each tablet is given every 30 days or monthly during mosquito season preferably on the same day every month. Dosing is based on body weight and this size is given to dogs weighing 51-100 lbs. Always speak to your veterinarian if you have questions about the proper use of Tri-Heart Plus.

Ivermectin will eventually kill immature heartworms and Pyrantel pamoate will eventually cause adult hookworms and roundworms to die by causing paralysis of the susceptible parasites.

Heartgard Plus is a monthly, FDA-Approved, pet medication for the prevention of heartworm disease. Heartgard Plus is 100% effective against heartworms; and it controls roundworms and hookworms. Heartgard Plus treats and controls more effectively than the next leading brand and is veterinarian recommended.

Heartgard Plus is approved for puppies as young as 6 weeks of age. Help your pet by ordering Heartgard Plus today. Key Benefits Highly effective in preventing heartworms Prevents development of adult stage heartworms Treats and controls both hookworms and roundworms Convenient, chewable form for easy administration Delicious beef flavor that most dogs will eat Indications For use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense).

How It Works Heartgard Plus prevents heartworm disease by eliminating the tissue stage of heartworm larvae for a month after infection. Treating your dog with Heartgard Plus is as easy as feeding one chewable a month.

Safe-Guard (fenbendazole) Canine Dewormer is for the treatment and control of Roundworms, Hookworms, Whipworms and Taenia Tapeworms in dogs. Safe-Guard Canine is the only over-the-counter dewormer for dogs that treats all 4 major intestinal parasites in dogs using only one drug compound, fenbendazole, minimizing your dogs chemical exposure.

The daily dose for Safe-Guard Canine is 50 mg/kg (22. 7 mg/lb) of body weight. Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism. Approximately 1% of dogs had vomiting associated with the use of this product.

Safe-Guard Canine Dewormer has no known interactions and is an ideal complement to monthly heartworm prevention products, which may not protect against all four major types of intestinal worms.

Heartworm Preventatives, Sentinel is a monthly preventative that protects your pet against heartworms, roundworms, hookworms, and whipworms. It also prevents flea eggs from hatching and developing into biting adult fleas.

Sentinel comes in an easy-to-administer chewable tablet and most dogs love the taste.

Interceptor Plus Heartworm Prevention Chewables are used to prevent heartworm disease, and for the treatment and control of adult roundworms, adult hookworms, adult whipworms, and adult tapeworms in dogs and puppies.

Interceptor Plus contains milbemycin oxime and praziquantel in a palatable chewable given once per month. Approved for dogs and puppies at least 2 lbs. and 6 weeks of age.

Sentinel Flavor Tabs are heartworm medicine for dogs and puppies. Kills fleas, roundworms, hookworms and whipworms. Contains lufenuron and milbemycin oxime.

Trifexis from Elanco is a preventative heartworm medication and flea killer. The Trifexis formula also prevents flea infestation and hookworm and roundworm infections. This monthly medication comes in a beef-flavored tablet that your dog is sure to love.

IVERHART Plus (ivermectin/pyrantel) Flavored Chewables for use in dogs to prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for a month (30 days) after infection and for the treatment and control of ascarids (Toxocara canis, Toxascaris leonina) and hookworms (Ancylostoma caninum, Uncinaria stenocephala, Ancylostoma braziliense).

See the Allivet Heartworm Comparison chart to find which heartworm prevention is best for your pet.

What are Iverhart Plus Flavored Chewables for Dogs? Iverhart Plus Chewables are a prescription heartworm preventative for dogs containing the antiparasitics Ivermectin and Pyrantel Pamoate. – Iverhart Plus Chewables also treat and control hookworms and roundworms.

– Tasty Iverhart Plus chewables for dogs prevent heartworm infection for a full month with one dose. Why do dogs use Iverhart Plus? Prescription Iverhart Plus chewables contain the highly effective active ingredients Ivermectin and Pyrantel Pamoate, which prevent heartworm infection by killing the parasite at the larval stage.

They also control and kill roundworms and hookworms. By giving your dog a chewable once a month on the same day, you’ll have peace of mind knowing that your dog is protected from dangerous heartworm and other parasites.

What else should I know about Iverhart Plus? Effectively kills heartworm, hookworm, and roundworm. – Pork liver flavor chewables dogs love. – Convenient once-a-month dosing. – Looking for Iverhart Max Soft Chews for Dogs? The American Heartworm Society and most veterinarians recommend an annual heartworm test before prescribing a heartworm preventative for your dog.

Dogs with heartworms are at risk for serious reactions if they take Ivermectin. – Iverhart Plus is sold as a prescription drug in a maximum of a 12-month supply per dog per year. – To buy the same size for more than one dog, add what you need to the cart.

You can split the amount to different dogs in checkout! Contact your local waste management about the safe disposal of Iverhart Plus. Iverhart Plus can be very toxic to fish and wildlife. What problems could my dog have with Iverhart Plus? Keep out of reach of other animals.

Overdoses can also be serious. Contact your veterinarian if you suspect an overdose. – Contact your veterinarian immediately if you see neurologic signs such as coma, weakness, clumsiness, dilated pupils, trembling, excessive drooling, or if your dog presses its head against the wall.

How do you use Iverhart Plus? Iverhart Plus chewables may be given with or without food. Follow your veterinarian’s directions. – It is best if your dog chews the Iverhart Plus before swallowing. If your dog normally swallows treats whole without chewing, you may break the chewable into pieces to feed your dog or add them to a small amount of food.

Discuss your options with your veterinarian. What is in Iverhart Plus? The active ingredients in Iverhart Plus are Ivermectin and Pyrantel Pamoate. – Ivermectin and Pyrantel Pamoate control and kill certain parasites like heartworms, hookworrms, and roundworms.

Will I get what I see in the picture? Iverhart Plus is a brand name. You will receive the exact brand that you request. Is it important for my dog to finish all of the Iverhart Plus? Dogs may use Iverhart Plus for different lengths of time.

3/18/2026 JG.

Interceptor flavor tabs are indicated for use in the prevention of heartworm disease caused by Dirofilaria Immitis, the control of adult hookworms, and the removal and control of adult roundworms and whipworm infections in dogs, puppies four weeks of age or greater and two pounds body weight or greater, as well as cats.

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Protect your dogs from heartworms, roundworms or hookworms with Triheart Plus 26-50 lb. for dogs. Triheart Plus flavored chewable tablets contain ivermectin/pyrantel. The combination of medications in Triheart Plus 26-50 lb.

for dogs has been proven to protect your dog from parasitic infestations when administered once a month.

Sentinel Spectrum is indicated for use in dogs and puppies, four weeks of age and older, and two pounds body weight or greater. SENTINEL for dogs is used for the prevention of heartworm disease and for the prevention and control of flea populations, the control of adult hookworm, and the removal and control of adult roundworm and whipworm infections.

Revolution (Selamectin) is a safe and simple monthly topical medication used to protect your dog or cat from heartworms, fleas, and ear mites. Revolution (Selamectin) is also used on dogs for the treatment or prevention of fleas, the American Dog Tick, ear mites, and canine sarcoptic mange.

When used on cats it is also used to treat or prevent fleas, ear mites, hookworms, and roundworms. Key Benefits Protects your pet from heartworms and fleas Fights both internal and surface parasitic infections Treats Sarcoptic mange in dogs Treats and controls ear mites Controls American Dog Tick infestation Treats and controls roundworms and hookworms in cats Only administered once a month Safe and easy to use Indication: Revolution is recommended for use in dogs six weeks of age or older.

Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations.

Revolution also is indicated for the treatment and control of sarcoptic mange (Sarcoptes scabiei) and for the control of tick infestations due to Dermacentor variabilis. How It Works Revolution works by penetrating the skin and entering your pet’s bloodstream.

Concentrations of selamectin, the active ingredient, in the tissue and bloodstream prevent heartworm disease. Selamectin also redistributes into the skin from the bloodstream and kills adult fleas, American dog ticks, and ear mites, and prevents flea eggs from hatching.

It is also an anthelmintic, which means it fights to expel parasitic worms. Parasites ingest the drug when they feed on the animal’s blood.

Sentinel Spectrum is indicated for use in dogs and puppies, four weeks of age and older, and two pounds body weight or greater. SENTINEL for dogs is used for the prevention of heartworm disease and for the prevention and control of flea populations, the control of adult hookworm, and the removal and control of adult roundworm and whipworm infections.

Revolution (Selamectin) is a safe and simple monthly topical medication used to protect your dog or cat from heartworms, fleas, and ear mites. Revolution (Selamectin) is also used on dogs for the treatment or prevention of fleas, the American Dog Tick, ear mites, and canine sarcoptic mange.

When used on cats it is also used to treat or prevent fleas, ear mites, hookworms, and roundworms. Key Benefits Protects your pet from heartworms and fleas Fights both internal and surface parasitic infections Treats Sarcoptic mange in dogs Treats and controls ear mites Controls American Dog Tick infestation Treats and controls roundworms and hookworms in cats Only administered once a month Safe and easy to use Indication: Revolution is recommended for use in dogs six weeks of age or older.

Revolution kills adult fleas and prevents flea eggs from hatching for one month and is indicated for the prevention and control of flea infestations (Ctenocephalides felis), prevention of heartworm disease caused by Dirofilaria immitis, and the treatment and control of ear mite (Otodectes cynotis) infestations.

Revolution also is indicated for the treatment and control of sarcoptic mange (Sarcoptes scabiei) and for the control of tick infestations due to Dermacentor variabilis. How It Works Revolution works by penetrating the skin and entering your pet’s bloodstream.

Concentrations of selamectin, the active ingredient, in the tissue and bloodstream prevent heartworm disease. Selamectin also redistributes into the skin from the bloodstream and kills adult fleas, American dog ticks, and ear mites, and prevents flea eggs from hatching.

It is also an anthelmintic, which means it fights to expel parasitic worms. Parasites ingest the drug when they feed on the animal’s blood.

Sentinel Spectrum is indicated for use in dogs and puppies, four weeks of age and older, and two pounds body weight or greater. SENTINEL for dogs is used for the prevention of heartworm disease and for the prevention and control of flea populations, the control of adult hookworm, and the removal and control of adult roundworm and whipworm infections.

Every purchase comes with 6 treatments that are specially formulated for canine companions 8 weeks of age and older, weighing between 11. 1 and 22 pounds. Simparica Trio is the first and only product that combines sarolaner, moxidectin and pyrantel in each treatment to help prevent heartworm disease, kill fleas before they can lay eggs, kill 5 types of ticks, treat and prevent flea infestations and treat and control roundworms and hookworms.

And each monthly chewable tablet has a palatable liver flavor and can be taken with or without food!.

MilbeGuard Flavored Tablets for Dogs are indicated for use in the prevention of heartworm disease caused by Dirofilaria immitis, the control of adult Ancylostoma caninum (hookworm), and the removal and control of adult Toxocara canis and Toxascaris leonina (roundworms) and Trichuris vulpis (whipworm) infections in dogs and in puppies four weeks of age or greater and two pounds body weight or greater.

MilbeGuard Flavored Tablets for Cats are indicated for use in the prevention of heartworm disease caused by Dirofilaria immitis, and the removal of adult Ancylostoma tubaeforme (hookworm) and Toxocara cati (roundworm) in cats and kittens six weeks of age or greater and 1.

5 lbs. body weight or greater.

Interceptor flavor tabs are indicated for use in the prevention of heartworm disease caused by Dirofilaria Immitis, the control of adult hookworms, and the removal and control of adult roundworms and whipworm infections in dogs, puppies four weeks of age or greater and two pounds body weight or greater, as well as cats.

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