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20 Best Flea And Tick Medicine For Cats (2022 Updated)

There are a variety of flea and tick medicines for cats available on the market. Some of these products are topical solutions that are applied to the cat’s skin, while others are oral medications. The type of product that you choose for your cat will depend on a number of factors, including your cat’s age, health, and lifestyle.

20 Best Flea And Tick Medicine For Cats

Product Image Product Name Features Price

CrossBlock II Flea Preventative for Cats 5-9 lbs 3-Pack

  • 5-9 lbs

TevraPet Actispot II Flea Prevention for Cats- 6 Doses

  • Large

Catego for Cats Over 1.5 lbs 3 Pack

  • Kills adult fleas, flea eggs, flea larvae, ticks and chewing lice
  • Kills fleas within 6 hours, Kills ticks through contact so they do not have to bite to die

Frontline Plus Flea, Tick & Lice Killer, for Cats – 3 doses

  • Kills all existing fleas on your pet within 18 hours
  • Each application provides a full month of protection
  • Also aids in the control of sarcoptic mange infections

Capstar Flea Tablets for Cats 2-25 lbs, 6 Count

  • Pack Of 6

Elanco Cheristin for Cats – 6 count

  • 6 Ct

Advantage II Flea Prevention for Large Cats, 1 Monthly Treatment

  • Large

Capstar Flea Oral Treatment for Cats, 2-25 lbs, 6 Tablets

  • Kills adult fleas to help prevent infestations on cats and kittens weighing between 2-25 pounds.
  • Capstar is formulated to start killing fleas within just 30 minutes to help give felines fast-acting relief.

Tevrapet FirstAct Plus Flea & Ticks Prevention, for Cats – 3 pack, 0.017 fl oz applicators

  • Kills adult fleas, flea eggs & flea larvae, ticks & chewing lice. Breaks the flea life cycle.
  • Kills ticks & chewing lice.

PetAction Plus Flea and Tick Treatment for Cats, over 1.5 lbs

  • 0.017 Fl Oz

Catego for Cats +1.5Lbs

  • FAST RELIEF: Catego kills fleas in just 6 hours compared to other brands that take 12 hours
  • LONG LASTING MEDICINE: Your cat will be rid of those unwanted guests for 30 days

Advantage II Once-A-Month Topical Large Cat Flea Treatment – 2 count

  • Fast acting, once a month topical flea prevention and treatment for cats that kills fleas within 12 hours of application

Advecta II Flea Treatment for Small Cat, 4 Monthly Treatments

  • 0.014 Fl Oz

Seresto Flea and Tick Prevention Collar for Cats, 8 Month Flea and Tick Prevention, Size: Cat, 15- Collar

  • Single Item

Vectra Green for Large Cats Over 9 Pounds USA Version EPA Registered

  • Can be used on cats as young as 8 weeks of age.
  • Fast acting. kills fleas in 6 hours. Fleas do not have to bite.
  • Quick drying and non-greasy formula. Convenient topical treatment with patented applicator.

Frontline Plus Flea and Tick Control for Cats Kittens, 6 Doses

  • Designed for use only with cats and kittens, this long-lasting treatment is made for cats eight weeks or older, weighing 1.5 pounds or more.

Sentry Advance Guard2 for Cats 5 to 9 lbs, 4 count

  • Once-a-month topical treatment for fleas on cats
  • Waterproof formula starts working through contact
  • Kills fleas, flea eggs and flea larvae

Adventure Plus for Cats 4-Pack

  • 4 Month Supply (9+ Lbs.)

Revolt (selamectin) for Cats 5.1-15 lbs, 6 Month Supply

  • 15 lbs, 6 Month
CrossBlock II Flea Preventative for Cats 5-9 lbs 3-Pack
  • 5-9 lbs
TevraPet Actispot II Flea Prevention for Cats- 6 Doses
  • Large
Catego for Cats Over 1.5 lbs 3 Pack
  • Kills adult fleas, flea eggs, flea larvae, ticks and chewing lice
  • Kills fleas within 6 hours, Kills ticks through contact so they do not have to bite to die
Frontline Plus Flea, Tick & Lice Killer, for Cats – 3 doses
  • Kills all existing fleas on your pet within 18 hours
  • Each application provides a full month of protection
  • Also aids in the control of sarcoptic mange infections
Capstar Flea Tablets for Cats 2-25 lbs, 6 Count
  • Pack Of 6
Elanco Cheristin for Cats – 6 count
  • 6 Ct
Advantage II Flea Prevention for Large Cats, 1 Monthly Treatment
  • Large
Capstar Flea Oral Treatment for Cats, 2-25 lbs, 6 Tablets
  • Kills adult fleas to help prevent infestations on cats and kittens weighing between 2-25 pounds.
  • Capstar is formulated to start killing fleas within just 30 minutes to help give felines fast-acting relief.
Tevrapet FirstAct Plus Flea & Ticks Prevention, for Cats – 3 pack, 0.017 fl oz applicators
  • Kills adult fleas, flea eggs & flea larvae, ticks & chewing lice. Breaks the flea life cycle.
  • Kills ticks & chewing lice.
PetAction Plus Flea and Tick Treatment for Cats, over 1.5 lbs
  • 0.017 Fl Oz
Catego for Cats +1.5Lbs
  • FAST RELIEF: Catego kills fleas in just 6 hours compared to other brands that take 12 hours
  • LONG LASTING MEDICINE: Your cat will be rid of those unwanted guests for 30 days
Advantage II Once-A-Month Topical Large Cat Flea Treatment – 2 count
  • Fast acting, once a month topical flea prevention and treatment for cats that kills fleas within 12 hours of application
Advecta II Flea Treatment for Small Cat, 4 Monthly Treatments
  • 0.014 Fl Oz
Seresto Flea and Tick Prevention Collar for Cats, 8 Month Flea and Tick Prevention, Size: Cat, 15- Collar
  • Single Item
Vectra Green for Large Cats Over 9 Pounds USA Version EPA Registered
  • Can be used on cats as young as 8 weeks of age.
  • Fast acting. kills fleas in 6 hours. Fleas do not have to bite.
  • Quick drying and non-greasy formula. Convenient topical treatment with patented applicator.
Frontline Plus Flea and Tick Control for Cats Kittens, 6 Doses
  • Designed for use only with cats and kittens, this long-lasting treatment is made for cats eight weeks or older, weighing 1.5 pounds or more.
Sentry Advance Guard2 for Cats 5 to 9 lbs, 4 count
  • Once-a-month topical treatment for fleas on cats
  • Waterproof formula starts working through contact
  • Kills fleas, flea eggs and flea larvae
Adventure Plus for Cats 4-Pack
  • 4 Month Supply (9+ Lbs.)
Revolt (selamectin) for Cats 5.1-15 lbs, 6 Month Supply
  • 15 lbs, 6 Month

1. CrossBlock II Flea Preventative for Cats 5-9 lbs 3-Pack

CrossBlock II Flea Preventative for Cats 5-9 lbs 3-Pack

  • 5-9 lbs

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Product Details

Specifications

Details
Is Discontinued By Manufacturer No
Package Dimensions 5.91 x 4.37 x 0.67 inches; 0.63 Ounces
Item Package Dimensions L x W x H 5.91 x 4.37 x 0.67 inches
Target Audience Keyword House-cats, Cat
Age Range Description Kittens

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2. TevraPet Actispot II Flea Prevention for Cats- 6 Doses

TevraPet Actispot II Flea Prevention for Cats- 6 Doses

  • Large

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Specifications

Details
Package Dimensions 7.36 x 4.57 x 1.3 inches; 2.9 Ounces
Country of Origin USA
Item Package Dimensions L x W x H 7.36 x 4.57 x 1.3 inches
Target Audience Keyword Cats, House-cats
Style 9+ lbs

3. Catego for Cats Over 1.5 lbs 3 Pack

Catego for Cats Over 1.5 lbs 3 Pack

  • Kills adult fleas, flea eggs, flea larvae, ticks and chewing lice
  • Kills fleas within 6 hours, Kills ticks through contact so they do not have to bite to die
  • Easy to apply spot-on patented applicator

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Product Details

Specifications

Details
Assembled Product Weight 0.10 lbs
Animal Type Cat
Assembled Product Dimensions (L x W x H) 1.00 x 5.50 x 5.00 Inches

4. Frontline Plus Flea, Tick & Lice Killer, for Cats – 3 doses

Frontline Plus Flea, Tick & Lice Killer, for Cats - 3 doses

  • Kills all existing fleas on your pet within 18 hours
  • Each application provides a full month of protection
  • Also aids in the control of sarcoptic mange infections
  • Great for pets that swim since it’s waterproof

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Product Details

Specifications

Details
Units in Package 3
Directions See insert for first aid and precautionary statements. It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your pet, read entire label and enclosed directions before each use. Follow all directions and precautionary statements carefully. Use on cats only. Do not use on rabbits. Do not use on other animals. To kill fleas, flea eggs & larvae, ticks, and chewing lice apply Frontline Plus for Cats as follows: To Remove Applicator: Lift and remove the plastic tab to expose foil backing; then peel away the foil. Or use scissors to open. Open applicator. Hold upright with foil side toward you and snap applicator tip. Apply Frontline Plus. Part the cat’s hair above the shoulder blades, at the base of the neck. Place the applicator tip just above the skin and squeeze. Apply entire contents of the applicator in a single spot directly onto the cat’s skin. Do not apply on top of the hair coat. Avoid contact with treated area until dry. Frontline Plus for Cats is approved for use on all cats, including breeding, pregnant, and lactating queens and kittens as young as 8 weeks. Frontline Plus remains effective even after bathing, water immersion, or exposure to sunlight. Frequency of Application: When used monthly, Frontline Plus completely breaks the flea life cycle and controls tick and chewing lice infestations. Do not reapply Frontline Plus for 30 days. Frontline Plus kills adult fleas, flea eggs, and flea larvae for up to six weeks. Frontline Plus also prevents development of all flea stages for up to six weeks. Frontline Plus can control fleas for up to six weeks, however, if there is a high risk of reinfestation or if the cat has fleas which may cause flea allergy dermatitis, a once monthly application may be needed. Frontline Plus kills ticks for at least one month. A once monthly application is recommended where tick control is needed. Frontline Plus kills all life stages of ticks (larva, nymph and adult). Frontline Plus kills ticks that may transmit Lyme disease, Rocky Mountain spotted fever, ehrlichiosis, babesiosis, anaplasmosis, haemobartonellosis and other tick-borne diseases. Frontline Plus kills chewing lice for at least one month. A once monthly application is recommended where chewing lice control is needed.
Ingredients Active Ingredients: Fipronil (9.8%), (S)-Methoprene (11.8%). Inert Ingredients: (78.4%).
Warnings Keep out of reach of children.

5. Capstar Flea Tablets for Cats 2-25 lbs, 6 Count

Capstar Flea Tablets for Cats 2-25 lbs, 6 Count

  • Pack Of 6

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6. Elanco Cheristin for Cats – 6 count

Elanco Cheristin for Cats - 6 count

  • 6 Ct

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Specifications

Details
Weight 3.2 oz

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THall

7. Advantage II Flea Prevention for Large Cats, 1 Monthly Treatment

Advantage II Flea Prevention for Large Cats, 1 Monthly Treatment

  • Large

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Specifications

Details
Imidacloprid 9.10%
Pyriproxyfen 0.46%
Other Ingredients 90.44%

8. Capstar Flea Oral Treatment for Cats, 2-25 lbs, 6 Tablets

Capstar Flea Oral Treatment for Cats, 2-25 lbs, 6 Tablets

  • Kills adult fleas to help prevent infestations on cats and kittens weighing between 2-25 pounds.
  • Capstar is formulated to start killing fleas within just 30 minutes to help give felines fast-acting relief.
  • This treatment can also help quickly treat flea infestations.
  • Capstar can be given to your cat companion as often as once a day.
  • Easy-to-give tablets are mess-free and odor-free, unlike some topical solutions.

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Product Details

Specifications

Details
Active Ingredients Nitenpyram
Animal Type Cat
Breed Size Small, Medium, Large
Effective Time Period Effective in 30 minutes
Manufacturer Brand Capstar

9. Tevrapet FirstAct Plus Flea & Ticks Prevention, for Cats – 3 pack, 0.017 fl oz applicators

Tevrapet FirstAct Plus Flea & Ticks Prevention, for Cats - 3 pack, 0.017 fl oz applicators

  • Kills adult fleas, flea eggs & flea larvae, ticks & chewing lice. Breaks the flea life cycle.
  • Kills ticks & chewing lice.
  • Kills all stages of ticks, including those that may transmit Lyme disease.
  • Continuous one month pest protection.
  • Fast acting, long lasting, easy to use.

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Specifications

Details
Units in Package 3
Unit Size 0.017 fl oz applicators
Directions Use only on cats weighing over 1.5 lbs. lbs. and over 8 weeks or older. Directions for Use: It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your cat, read the entire label and package insert before each use. Follow all directions and precautionary statement carefully use on cats only. do not use on rabbits or other animals. Restrictions: Do not use on dogs, rabbits, or other animals. Do not apply more than once every 30 days. Do not bathe or allow your cat to swim for 24 hours after application. Do not allow your cat to ingest this product. Do not use on kittens under 8 weeks of age or weighing less than 1.5 lbs. Do not apply more than one applicator per treatment for one cat regardless of the cat’s weight. In multi-cat household, do not allows cats to groom each other until product has dried. Frequency of Application: Fleas: When used monthly, Tevrapet First Act Plus for cats kills all stages of the flea life cycle and prevents reinfestation of fleas on your cat for up to six weeks after application. Although Tevrapet FirstAct Plus for cats can control fleas up to six weeks, if there is a high risk of re-infestation of fleas on your cat, or if the cat has fleas which may cause flea allergy dermatitis, apply Tevrapet FirstAct Plus Cats once every 30 days. Chewing Lice: Tevrapet First Act for cats kills chewing lice for at least 30 days. For best control of chewing lice, apply once every 30 days. Do not reapply Tevrapet FirstAcit Plus for cats for 30 days. Storage and Disposal: Do not contaminate water, food, or feed by storage or disposal. Storage: Store in a cool, dry place. Protect from freezing. Pesticide Disposal and Container Handling: Nonrefillable container. If empty: Place in trash or offer for recycling if available.
Warnings Caution: See label insert for first aid, precautionary statements and complete directions for use. Keep out of reach of children. Side Effects: Monitor your cat after application. Side effects, although very rare, may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Although uncommon, gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects occur, consult your veterinarian or call 1-800-775-9416.

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Sadie
1 Cowhorse

10. PetAction Plus Flea and Tick Treatment for Cats, over 1.5 lbs

PetAction Plus Flea and Tick Treatment for Cats, over 1.5 lbs

  • 0.017 Fl Oz

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Product Details

Specifications

Details
Units in Package 3
Unit Size 0.017 fl oz tubes
Directions Directions for Use: It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your cat read entire label and directions before each use. Follow all directions and precautionary statements carefully. Use on cats only. Restrictions: Do not apply to cats under 8 weeks of age and weighing less than 1.5 lbs. Do not exceed listed dosage amount for cats. Do not allow your cat to ingest this product. Do not use on rabbits, dogs, puppies or other animals. Do not reapply PetAction Plus for cats for 30 days. Do not double-dose or apply more than one applicator tube per treatment for one cat regardless of the cat’s weight. Do not allow cats to groom each other until product has dried. To kill fleas, all stages of ticks (brown dog ticks, American dog ticks, lone star ticks, and deer ticks [which may carry Lyme disease]) and chewing lice, apply to cats and kittens 8 weeks or older weighing 1.5 lbs or more as follows: 1. Remove one applicator tube from the package and hold in an upright position pointed away from your face. 2. Pull off cap. Turn the cap around and place on top. 3. Simply press cap down to break the seal of the tube. Remove cap carefully. 4. Position the tip of the tube on the cat’s back between the shoulder blades. Use the tip of the tube to part the cat’s hair so that the product will be applied at skin level. Squeeze applicator, applying entire contents in a single spot on the cat’s skin. Separate treated cat from other pets for 24 hours after treatment has been applied. You may bathe your cat 48 hours after application. 5. Repeat every month. Frequency of Application: When used monthly, PetAction Plus for Cats completely breaks the flea life cycle and controls tick and chewing lice infestations. Research demonstrates that PetAction Plus for Cats kills adult fleas, flea eggs, and flea larvae for up to six weeks. PetAction Plus for Cats also prevents development of all flea stages for up to six weeks. Although PetAction Plus for Cats can control fleas for up to six weeks, if there is a high risk of reinfestation or if the cat has fleas which may cause flea allergy dermatitis, a once monthly application may be needed. PetAction Plus for Cats kills ticks for at least one month. A once monthly application is recommended where tick control is needed. PetAction Plus for Cats kills chewing lice for 30 days. Do not reapply product for 30 days. PetAction Plus for Cats remains effective even after bathing, swimming, water immersion, or exposure to sunlight. Avoid contact with treated are until dry. Do not reapply PetAction Plus for cats for 30 days. Storage and Disposal: Do not contaminate water, food, or feed by storage or disposal. Do not use or store neat heat or open flame. Pesticide Storage: Keep this product in its tightly closed original container, when not in use. Store in a cool, dry (preferably locked) area that is inaccessible to children and animals. Pesticide Disposal: Wastes resulting from the use of this product may be disposed of on site or at an approved waste disposal facility. Container Handling: Non-refillable container. Do not reuse or refill this container. If Empty: Offer for recycling, if available or place in trash. If Partly Filled: Call your local solid waste agency for disposal instructions. Never place unused product down any indoor or outdoor drain. Side Effects: Monitor your cat after application. Side effects may include signs of skin irritation such as redness, scratching, or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects occur, consult your veterinarian or call 1-855-844-4375.
Ingredients Active Ingredients: Fipronil (9.80%), (S)-Methoprene (11.80%). Other Ingredients: (78.40%).
Warnings Keep out of reach of children. Caution: See back panel for first aid and additional precautionary statements. Precautionary Statements: Hazards to humans. Caution. Harmful if swallowed. Causes eye irritation. Avoid contact with skin, eyes or clothing. Wash hands thoroughly with soap and water after handling and before eating, drinking, chewing gum, using tobacco or using the toilet. Hazards to domestic animals. For external use only. Do not use on kittens under 8 weeks of age or weighing less than 1.5 lbs. Sensitivities may occur after using any pesticide product for cats. If signs of sensitivity occur, bathe your cat with mild soap and rinse with large amounts of water. If signs continue, consult a veterinarian immediately. Cats may experience some temporary irritation at the site of product application. Consult a veterinarian before using this product on medicated, debilitated or aged cats. Call 1-855-844-4375 for 24-hour assistance. Physical or Chemical Hazards: Combustible: Do not use or store neat heat or open flame. First Aid – If Swallowed: Call a poison control center or doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything by mouth to an unconscious person. If in Eyes: Hold eye open and rinse slowly and gently with water for 15-20 minutes. Remove contact lenses, if present, after the first 5 minutes, then continue rinsing eye. Call a poison control center or doctor for treatment advice. If on Skin or Clothing: Take off contaminated clothing. Rinse skin immediately with plenty of water for 15-20 minutes. Call a poison control center or doctor for treatment advice. Hot Line Number: have the product container or label with you when calling a poison control center or doctor, or going for treatment. For additional information on this product including health concerns, medical emergencies or pesticide incidents, you may call 1-855-844-4375, twenty-four (24) hours per day, seven (7) days per week.

11. Catego for Cats +1.5Lbs

Catego for Cats +1.5Lbs

  • FAST RELIEF: Catego kills fleas in just 6 hours compared to other brands that take 12 hours
  • LONG LASTING MEDICINE: Your cat will be rid of those unwanted guests for 30 days
  • ACTIVE INGREDIENTS: Catego has a unique combination of three proven active ingredients; Dinotefuran, Fipronil, and Pyriproxyfen

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Specifications

Details
Product Form Solution

12. Advantage II Once-A-Month Topical Large Cat Flea Treatment – 2 count

Advantage II Once-A-Month Topical Large Cat Flea Treatment - 2 count

  • Fast acting, once a month topical flea prevention and treatment for cats that kills fleas within 12 hours of application
  • For use only on cats 8 weeks and older and weighing over 9 pounds
  • Controls existing flea infestations on your cat and prevents further infestations – fleas do not have to bite your cat to die
  • Fragrance-free and waterproof topical flea solution that’s convenient and easy to apply
  • Kills all flea life stages

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13. Advecta II Flea Treatment for Small Cat, 4 Monthly Treatments

Advecta II Flea Treatment for Small Cat, 4 Monthly Treatments

  • 0.014 Fl Oz

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Specifications

Details
Manufacturer Part Number 818145015212
Product Name Flea/Tick Control Drop
Product Type Flea/Tick Control Drop
Animal Type Cat
Minimum Pet Weight 5 lb

14. Seresto Flea and Tick Prevention Collar for Cats, 8 Month Flea and Tick Prevention, Size: Cat, 15- Collar

Seresto Flea and Tick Prevention Collar for Cats, 8 Month Flea and Tick Prevention, Size: Cat, 15- Collar

  • Single Item

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Specifications

Details
Product Type Flea and Tick Collar
Product Form Solid
Animal Type Cat
Odorless Yes
Organic No

15. Vectra Green for Large Cats Over 9 Pounds USA Version EPA Registered

Vectra Green for Large Cats Over 9 Pounds USA Version EPA Registered

  • Can be used on cats as young as 8 weeks of age.
  • Fast acting. kills fleas in 6 hours. Fleas do not have to bite.
  • Quick drying and non-greasy formula. Convenient topical treatment with patented applicator.
  • Kills fleas that may cause flea allergy dermatitis(FAD), anemiacause, may transmit disease, including bartonellosis, tapeworm and tularemia.
  • Each monthly dose controls development of all flea stages; Prevents, controls and stops flea infestation and prevents re-infestation.

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16. CapAction Oral Flea Treatment for Cats Under 25lbs.

CapAction Oral Flea Treatment for Cats Under 25lbs.

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Revival Animal Health

Product Details

Specifications

Details
Assembled Product Weight 0.05 lb
Animal Type Cat
Assembled Product Dimensions (L x W x H) 0.57 x 4.57 x 2.75 Inches

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Mkat

17. Frontline Plus Flea and Tick Control for Cats Kittens, 6 Doses

Frontline Plus Flea and Tick Control for Cats Kittens, 6 Doses

  • Designed for use only with cats and kittens, this long-lasting treatment is made for cats eight weeks or older, weighing 1.5 pounds or more.
  • Made with two active ingredients, fipronil and (S)-methoprene, this treatment stops infestations and prevents new ones.
  • One dose of FRONTLINE Plus lasts 30 days.
  • Flea, flea egg, lice, and tick control for cats and kittens.

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Specifications

Details
Animal Cat
Ingredient Fipronil, (S)-Methoprene, Pyriproxyfen
Country Of Origin USA
Pest Type FleasTicksLice

18. Sentry Advance Guard2 for Cats 5 to 9 lbs, 4 count

Sentry Advance Guard2 for Cats 5 to 9 lbs, 4 count

  • Once-a-month topical treatment for fleas on cats
  • Waterproof formula starts working through contact
  • Kills fleas, flea eggs and flea larvae

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Specifications

Details
Directions Follow all package directions for application.
Assembled Product Weight 0.1 lbs
Animal Type Cat
Assembled Product Dimensions (L x W x H) 6.00 x 5.50 x 1.50 Inches

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19. Adventure Plus for Cats 4-Pack

Adventure Plus for Cats 4-Pack

  • 4 Month Supply (9+ Lbs.)

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DuraPro Health
VIC Pharmacy

Product Details

Specifications

Details
Age range description All Life Stages
Is Discontinued By Manufacturer No
Product Dimensions 1.34 x 4.28 x 4.7 inches; 0.06 Ounces

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20. Revolt (selamectin) for Cats 5.1-15 lbs, 6 Month Supply

Revolt (selamectin) for Cats 5.1-15 lbs, 6 Month Supply

  • 15 lbs, 6 Month

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Conclusion

The conclusion of flea and tick medicine for cats is that it is an effective way to protect your cat from these pests.

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