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20 Best Cream For Cold Sores (2022 Updated)

Cream for cold sores is a topical ointment that is used to treat the symptoms of cold sores. The cream typically contains a combination of ingredients such as lidocaine, which numbs the pain, and acyclovir, which helps to speed up the healing process.

Cold sores are caused by the herpes simplex virus and can be extremely painful. The cream can help to soothe the pain and help the cold sore to heal more quickly.

20 Best Cream For Cold Sores

Product Image Product Name Features Price

Releev Cold Sore Symptom Treatment, 1 Day – 6 ml

  • Over-the-counter cold sore cream
  • Relieves symptoms in just one day
  • Treats cold sores and fever blisters

Quantum Super Lysine And Cold Stick Lip Protector And Cold Sore Treatment – 0.18 oz stick

  • Super Lysine Plus+ Coldstick, .18 oz sticks Use everyday to protect your lips from the sun, a common cold sore trigger.
  • Contains all the same healing, relief giving and preventive nutrients as the ointment.

Abreva Cold Sore Treatment Cream, Docosanol 10% – 0.07 oz, 2 Pack

  • Pack of 2

Abreva Cold Sore/Fever Blister Treatment Cream – 0.07 oz pump

  • Only FDA Approved Medicine to Shorten Healing Time
  • You Could Knock Out Your Cold Sore in 2½ Days
  • Abreva Can Do It, When You Treat at the First Sign

Abreva Docosanol 10% Cream Cold Sore/Fever Blister Treatment Pump – 0.07oz

  • Specially developed to treat fever blisters and cold sores
  • Cream form offers convenient application
  • Its advanced formula helps reduce the healing time

Quantum Health Lip Clear Lysine Plus Cold Sore Treatment – 0.25 oz tube

  • Stops burning and itching
  • Fast pain relief
  • Cuts healing time in half

Abreva Docosanol 10% Cream Pump, Treatment for Cold Sore/Fever Blister, 0.07 Ounce

  • Healing cream for treating cold sores and fever blisters on the face or lips
  • Shortens the duration of tingling, pain, burning and itching symptoms

Abreva Abreva Cold Sore Treatment Cream Tube 2g 2.0 G

  • 2g docosanol
  • Non-prescription
  • Abreva cold sore medication 2g Canada Non-prescription docosanol GlaxoSmithKline

Burt's Bees Cold Sore Treatment, Rapid Rescue – 0.07 oz

  • Suggested Age: All Ages
  • Product Form: Liquid
  • Primary Active Ingredient: Menthol

Thursday Plantation Tea Tree Cold Sore Cream – 10g

  • Thursday Plantation Cold Sore Cream provides soothing relief of cold sores and sun blistered or chapped lips.
  • Made in Australia.

Orajel Cold Sore Symptom Treatment, Maximum Strength, MoistureLock Cream – 0.105 oz

  • Cream formulation glides smoothly on your skin for even application
  • Infused with active ingredients that offers fast relief from sores and pain

Anbesol Cold Sore Therapy, Maximum Strength – .33 oz

  • Topical Application.
  • Easy To Use.
  • Anbesol Cold Sore Therapy contains aloe, menthol and more all in a travel size tube.

Carmex Cold Sore Treatment – 0.07 oz

  • Creamy formula glides on smoothly to minimize appearance of cold sores
  • Helps promote healing of cold sores
  • Treats 7 symptoms on contact: Pain, Itch, Dryness, Cracking, Redness, Scabbing and Irritation

Quantum Lip Clear Lysine Plus Ointment, 7 Gram

  • 7 Grams Gel.
  • Cold Sore Treatment.
  • Cuts healing time in half!

Carmex Cold Sore Treatment, Multi-Symptom, 3 in 1 – 0.07 oz

  • Moisture Shield soothes and protects.
  • Dermatologist tested, Carmex Cold Sore Treatment temporarily relieves pain & itch.
  • Carmex cold sore treatment temporarily relieves pain and itching.

Campho-Phenique Cold Sore Treatment Gel, Maximum Strength, Medicated – 0.23 oz

  • Dry the cold sore without causing cracking.
  • Help prevent infections to promote healing.
  • Relieve the cold sore pain with a maximum strength pain reliever.

HERPATCH Cold Sore Serum 5ml

  • Herpatch Cold Sore Serum has instant effect
  • Treats every stage of the cold sore
  • The White Serum will form a patch over the wound

Galpharm Cold Sore Cream 2g

  • At tingling…
  • Or at blistering.
  • Speeds recovery.
Releev Cold Sore Symptom Treatment, 1 Day – 6 ml
  • Over-the-counter cold sore cream
  • Relieves symptoms in just one day
  • Treats cold sores and fever blisters
Quantum Super Lysine And Cold Stick Lip Protector And Cold Sore Treatment – 0.18 oz stick
  • Super Lysine Plus+ Coldstick, .18 oz sticks Use everyday to protect your lips from the sun, a common cold sore trigger.
  • Contains all the same healing, relief giving and preventive nutrients as the ointment.
Abreva Cold Sore Treatment Cream, Docosanol 10% – 0.07 oz, 2 Pack
  • Pack of 2
Abreva Cold Sore/Fever Blister Treatment Cream – 0.07 oz pump
  • Only FDA Approved Medicine to Shorten Healing Time
  • You Could Knock Out Your Cold Sore in 2½ Days
  • Abreva Can Do It, When You Treat at the First Sign
Abreva Docosanol 10% Cream Cold Sore/Fever Blister Treatment Pump – 0.07oz
  • Specially developed to treat fever blisters and cold sores
  • Cream form offers convenient application
  • Its advanced formula helps reduce the healing time
Quantum Health Lip Clear Lysine Plus Cold Sore Treatment – 0.25 oz tube
  • Stops burning and itching
  • Fast pain relief
  • Cuts healing time in half
Abreva Docosanol 10% Cream Pump, Treatment for Cold Sore/Fever Blister, 0.07 Ounce
  • Healing cream for treating cold sores and fever blisters on the face or lips
  • Shortens the duration of tingling, pain, burning and itching symptoms
Abreva Abreva Cold Sore Treatment Cream Tube 2g 2.0 G
  • 2g docosanol
  • Non-prescription
  • Abreva cold sore medication 2g Canada Non-prescription docosanol GlaxoSmithKline
Burt's Bees Cold Sore Treatment, Rapid Rescue – 0.07 oz
  • Suggested Age: All Ages
  • Product Form: Liquid
  • Primary Active Ingredient: Menthol
Thursday Plantation Tea Tree Cold Sore Cream – 10g
  • Thursday Plantation Cold Sore Cream provides soothing relief of cold sores and sun blistered or chapped lips.
  • Made in Australia.
Orajel Cold Sore Symptom Treatment, Maximum Strength, MoistureLock Cream – 0.105 oz
  • Cream formulation glides smoothly on your skin for even application
  • Infused with active ingredients that offers fast relief from sores and pain
Anbesol Cold Sore Therapy, Maximum Strength – .33 oz
  • Topical Application.
  • Easy To Use.
  • Anbesol Cold Sore Therapy contains aloe, menthol and more all in a travel size tube.
Carmex Cold Sore Treatment – 0.07 oz
  • Creamy formula glides on smoothly to minimize appearance of cold sores
  • Helps promote healing of cold sores
  • Treats 7 symptoms on contact: Pain, Itch, Dryness, Cracking, Redness, Scabbing and Irritation
Quantum Lip Clear Lysine Plus Ointment, 7 Gram
  • 7 Grams Gel.
  • Cold Sore Treatment.
  • Cuts healing time in half!
Carmex Cold Sore Treatment, Multi-Symptom, 3 in 1 – 0.07 oz
  • Moisture Shield soothes and protects.
  • Dermatologist tested, Carmex Cold Sore Treatment temporarily relieves pain & itch.
  • Carmex cold sore treatment temporarily relieves pain and itching.
Campho-Phenique Cold Sore Treatment Gel, Maximum Strength, Medicated – 0.23 oz
  • Dry the cold sore without causing cracking.
  • Help prevent infections to promote healing.
  • Relieve the cold sore pain with a maximum strength pain reliever.
HERPATCH Cold Sore Serum 5ml
  • Herpatch Cold Sore Serum has instant effect
  • Treats every stage of the cold sore
  • The White Serum will form a patch over the wound
Galpharm Cold Sore Cream 2g
  • At tingling…
  • Or at blistering.
  • Speeds recovery.

1. Releev Cold Sore Symptom Treatment, 1 Day – 6 ml

Releev Cold Sore Symptom Treatment, 1 Day - 6 ml

  • Over-the-counter cold sore cream
  • Relieves symptoms in just one day
  • Treats cold sores and fever blisters
  • Soothing, non-irritating formula
  • Available in a 5ml size

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Walgreens.com
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Product Details

Specifications

Details
Units in Package 1
Unit Size 6 ml
Indications Uses: Treats cold sores/fever blisters. For the pain, tingling, itching, & burning associated with cold sores. May be used as an antiseptic to help cleanse or dry cold sores & fever blisters. May be used inside the mouth on sores. .
Directions General directions: Shake well (Adults and children 12 years of age or older) apply to clean, dry, affected area 3-4 times per day by dabbing and pressing solution into the area well. Allow to dry. Best when used at first sign of outbreak. Do not use cotton applicator. Age group directions: :
Ingredients Active Ingredients: Benzalkonium Chloride (0.13 %). Purpose: Cold Sore/Fever Blister Treatment. Inactive Ingredients: Echinacea Purpurea [Viracea, Proprietary Blend of Benzalkonium Chloride and Echinacea Herb], Methyl Cellulose, Methyl Paraben, Potassium Sorbate, Propyl Paraben, Purified Water.

Reviews From Real Customers

jmfarro
Sparkel
funniebunnie

2. Quantum Super Lysine And Cold Stick Lip Protector And Cold Sore Treatment – 0.18 oz stick

Quantum Super Lysine And Cold Stick Lip Protector And Cold Sore Treatment - 0.18 oz stick

  • Super Lysine Plus+ Coldstick, .18 oz sticks Use everyday to protect your lips from the sun, a common cold sore trigger.
  • Contains all the same healing, relief giving and preventive nutrients as the ointment.
  • Convenient and Quick Cold Sore and Chapped Lip Relief with SPF-21 Sunblock Use everyday to protect your lips from the sun, a common cold sore trigger.

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Amazon.com – Seller
Walmart
Quantum Health
Organic Basic Food

Product Details

Specifications

Details
Rich Active Ingredients OCTINOXATE 7.0% ….. SUNSCREEN, OXYBENZONE (BENZOPHENONE-3) 5.0% ….. SUNSCREEN
Active Ingredients OCTINOXATE 7.0% ….. SUNSCREEN, OXYBENZONE (BENZOPHENONE-3) 5.0% ….. SUNSCREEN
Derived Nutrition Claim Salt Free
Derived Nutrition Claim Soy Free
Derived Nutrition Claim Paraben Free

Reviews From Real Customers

Mary K.

3. Abreva Cold Sore Treatment Cream, Docosanol 10% – 0.07 oz, 2 Pack

Abreva Cold Sore Treatment Cream, Docosanol 10% - 0.07 oz, 2 Pack

  • Pack of 2

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Details
Units in Package 2
Unit Size 2 g tubes
Indications Uses: Treats cold sores/fever blisters on the face or lips. Shortens healing time and duration of symptoms: tingling, pain, burning, and/or itching..
Directions Age group directions: Adults and Children 12 Years or Over: Wash hands before and after applying cream. Apply to affected area on face or lips at the first sign of cold sore/fever blister (tingle). Early treatment ensures the best results. Rub gently but completely. Use 5 times a day until healed. Children Under 12 Years: Ask a doctor.
Ingredients Active Ingredients: Docosanol (10 %). Purpose: Cold Sore/Fever Blister Treatment. Inactive Ingredients: Benzyl Alcohol, Light Mineral Oil, Propylene Glycol, Purified Water, Sucrose Distearate, Sucrose Stearate

4. Abreva Cold Sore/Fever Blister Treatment Cream – 0.07 oz pump

Abreva Cold Sore/Fever Blister Treatment Cream - 0.07 oz pump

  • Only FDA Approved Medicine to Shorten Healing Time
  • You Could Knock Out Your Cold Sore in 2½ Days
  • Abreva Can Do It, When You Treat at the First Sign
  • Portable Convenient Pump

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Amazon
eBay – carolina_otc
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MDMaxx

Product Details

Specifications

Details
Is Discontinued By Manufacturer ‏ ‎ No
Package Dimensions ‏ ‎ 5.3 x 4.5 x 1.3 inches; 0.63 Ounces
Package Dimensions ‎5.3 x 4.5 x 1.3 inches; 0.63 Ounces
Is Discontinued By Manufacturer ‎No

5. Abreva Docosanol 10% Cream Cold Sore/Fever Blister Treatment Pump – 0.07oz

Abreva Docosanol 10% Cream Cold Sore/Fever Blister Treatment Pump - 0.07oz

  • Specially developed to treat fever blisters and cold sores
  • Cream form offers convenient application
  • Its advanced formula helps reduce the healing time

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Amazon
eBay – threebynine
Target

Product Details

Specifications

Details
Product Form Cream
Dispenser Type Pump
Recommended Age Group Adult
Weight 0.07 oz

6. Quantum Health Lip Clear Lysine Plus Cold Sore Treatment – 0.25 oz tube

Quantum Health Lip Clear Lysine Plus Cold Sore Treatment - 0.25 oz tube

  • Stops burning and itching
  • Fast pain relief
  • Cuts healing time in half
  • Soothes and moisturizes

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Target
Quantum Health

Product Details

Specifications

Details
Active Ingredients MENTHOL 0.1% ….. COLD SORE / FEVER BLISTER TREATMENT
Ingredients BEESWAX, CALENDULA OFFICINALIS EXTRACT, ECHINACEA PURPUREA EXTRACT, GUM BENZOIN TINCTURE, HONEY, HYDRASTIS CANADENSIS (GOLDENSEAL) LEAF, LYSINE, MELALEUCA ALTERNIFOLIA OIL, MELALEUCA CAJUPUTI OIL, OLEA EUROPAEA (OLIVE) FRUIT OIL, PROPOLIS EXTRACT, VITAMIN A (RETINYL PALMITATE), VITAMIN D3, VITAMIN E (TOCOPHEROL), ZINC OXIDE.
Indications TEMPORARILY RELIEVES TINGLING, ITCHING, BURNING, BLISTERING, AND PAIN ASSOCIATED WITH COLD SORES/FEVER BLISTERS.
Other Information STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.
Other Information CLOSE COVER TIGHTLY AFTER EACH USE.

Reviews From Real Customers

jess.c
Devon
Best OTC medicine ever

7. Abreva Docosanol 10% Cream Pump, Treatment for Cold Sore/Fever Blister, 0.07 Ounce

Abreva Docosanol 10% Cream Pump, Treatment for Cold Sore/Fever Blister, 0.07 Ounce

  • Healing cream for treating cold sores and fever blisters on the face or lips
  • Shortens the duration of tingling, pain, burning and itching symptoms
  • Delivers best results when treated at the first tingle
  • Penetrates deep into the skin to the source of the spreading virus
  • Contains 2 grams of cream

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Details
Dimensions 1.6x5x5.45 inches

8. Quantum SupLysine+ Cold Sore Relief Cream – 0.75 oz tube

 Quantum SupLysine+ Cold Sore Relief Cream - 0.75 oz tube

  • This ointment helps reduce inflammation and burning for a calming effect
  • Its herb nutrient-based treatment soothes your skin for a pleasant feel
  • Cream formulation glides seamlessly for a precise and easy application

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Organic Basic Food
myotcstore.com

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Specifications

Details
Container Type Tube
Product Form Cream
Petroleum-Free Yes

9. Abreva Abreva Cold Sore Treatment Cream Tube 2g 2.0 G

Abreva Abreva Cold Sore Treatment Cream Tube 2g 2.0 G

  • 2g docosanol
  • Non-prescription
  • Abreva cold sore medication 2g Canada Non-prescription docosanol GlaxoSmithKline

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Amazon
CTC Health
eCrater – dropshipper9

Product Details

10. Burt’s Bees Cold Sore Treatment, Rapid Rescue – 0.07 oz

Burt's Bees Cold Sore Treatment, Rapid Rescue - 0.07 oz

  • Suggested Age: All Ages
  • Product Form: Liquid
  • Primary Active Ingredient: Menthol
  • Package Quantity: 1
  • Net weight: .07 Ounces

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Burt’s Bees

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Details
Units in Package 1
Unit Size 0.07 oz

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Lexie
martha.d
Madelynn

11. Thursday Plantation Tea Tree Cold Sore Cream – 10g

Thursday Plantation Tea Tree Cold Sore Cream - 10g

  • Thursday Plantation Cold Sore Cream provides soothing relief of cold sores and sun blistered or chapped lips.
  • Made in Australia.
  • Contains 100% pure Australia Tea Tree Oil.
  • Free from polysorbates, mineral oils, propylene glycol, SLS, synthetic fragrances, synthetic colours, synthetic preservatives and synthetic parabens.
  • Product not tested on animals.

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Phragos Health and Beauty

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Details
Handling Time Ships within 1 to 3 business days

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Liz NZ
Jess100095
LJxo18

12. Orajel Cold Sore Symptom Treatment, Maximum Strength, MoistureLock Cream – 0.105 oz

Orajel Cold Sore Symptom Treatment, Maximum Strength, MoistureLock Cream - 0.105 oz

  • Cream formulation glides smoothly on your skin for even application
  • Infused with active ingredients that offers fast relief from sores and pain
  • Its advanced formula helps keep your skin moisturized

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Details
Container Type Tube
Weight 0.105 oz
Product Form Cream

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Tinaalbs
Nelly
Courtney Elizabeth

13. Abreva Cold Sore/Fever Blister Treatment.07-Ounce Tube

Abreva Cold Sore/Fever Blister Treatment.07-Ounce Tube

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iBeautyCity.com

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Product Dimensions 2.75 x 0.5 x 5.95 inches

14. Anbesol Cold Sore Therapy, Maximum Strength – .33 oz

Anbesol Cold Sore Therapy, Maximum Strength - .33 oz

  • Topical Application.
  • Easy To Use.
  • Anbesol Cold Sore Therapy contains aloe, menthol and more all in a travel size tube.

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Amazon
Rite Aid

Product Details

Specifications

Details
Units in Package 1
Unit Size .33 oz
Indications Temporarily relieves pain associated with fever blisters and cold sores, relieves dryness and softens fever blisters and cold sores.
Directions To open tube, cut tip of tube on score mark with scissors. Adults and Children 2 Years of Age and Older: Apply to the affected area not more than 3 to 4 times daily. Children Under 12 Years of Age: Adult supervision should be given in the use of this product. Children Under 2 Years of Age: Consult a doctor. Store at 20-25 degrees C (68-77 degrees F).
Ingredients Active Ingredients: Allantoin (1%), Benzocaine (20%), Camphor (3%), White Petrolatum (64.9%). Inactive Ingredients: Aloe Extract, Benzyl Alcohol, Butylparaben, Glyceryl Stearate, Isocetyl Stearate, Menthol, Methylparaben, Propylparaben, Sodium Lauryl Sulfate, Vitamin E, White Wax.

Reviews From Real Customers

jessica.l
john.jorda
perce8673

15. Carmex Cold Sore Treatment – 0.07 oz

Carmex Cold Sore Treatment - 0.07 oz

  • Creamy formula glides on smoothly to minimize appearance of cold sores
  • Helps promote healing of cold sores
  • Treats 7 symptoms on contact: Pain, Itch, Dryness, Cracking, Redness, Scabbing and Irritation
  • Recommended for adults and children 2 years of age and older

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DrugSuppyStore.com

Product Details

Specifications

Details
Units in Package 1
Unit Size 0.07 oz

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KT Gold
Nick Bozarth
zahara.m

16. Quantum Lip Clear Lysine Plus Ointment, 7 Gram

Quantum Lip Clear Lysine Plus Ointment, 7 Gram

  • 7 Grams Gel.
  • Cold Sore Treatment.
  • Cuts healing time in half!

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Paragon Essentials

Product Details

Specifications

Details
Product Dimensions 6 x 6 x 6 inches; 0.64 Ounces
Country of Origin USA

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A Google user provided by Google
Kim Placentino
Ashley Selman

17. Carmex Cold Sore Treatment, Multi-Symptom, 3 in 1 – 0.07 oz

Carmex Cold Sore Treatment, Multi-Symptom, 3 in 1 - 0.07 oz

  • Moisture Shield soothes and protects.
  • Dermatologist tested, Carmex Cold Sore Treatment temporarily relieves pain & itch.
  • Carmex cold sore treatment temporarily relieves pain and itching.
  • Formulated with benzocaine, this cold sore treatment is an external analgesic and skin protectant.

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Bed Bath & Beyond

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Details
Units in Package 1
Unit Size 0.07 oz
Indications Uses: Uses for temporary relief of pain and itching associated with symptoms of fever blisters and cold sores; helps prevent and protect dry, chapped lips.
Directions General directions: Using clean, dry hands apply 1 to 2 small dollops of Carmex Cold Sore product to the tip of the finger and gently apply and spread evenly to the surface of the cold sore to ensure even coverage over areas of redness. Wash hands thoroughly after application. Age group directions: Adults and Children 2 Years of Age and Older: Apply to affected area (lips) not more than 3 to 4 times daily. Children 2-12 Years of Age: Should be Supervised in use of this product. Children under 2 Years of Age: Ask a doctor.
Ingredients Active Ingredients: Benzocaine (10 %), White Petrolatum (44.69 %). Purpose: External Analgesic, Skin Protectant. Inactive Ingredients: Polyethylene Glycol, Hdi/Trimethylol Hexyllactone Crosspolymer, Titanium Dioxide, Behenyl Olivate, PPG-51 SMDI Copolymer, Mica, Synthetic Wax, Calcium Silicate, Flavor, Isopropyl Titanium Triisostearate, Silica, Tin Oxide, Iron Oxides (CI 77491, CI 77492, CI 77499)

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Judith Rehling
mollie bridget.y

18. Campho-Phenique Cold Sore Treatment Gel, Maximum Strength, Medicated – 0.23 oz

Campho-Phenique Cold Sore Treatment Gel, Maximum Strength, Medicated - 0.23 oz

  • Dry the cold sore without causing cracking.
  • Help prevent infections to promote healing.
  • Relieve the cold sore pain with a maximum strength pain reliever.

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CVS Pharmacy

Product Details

Specifications

Details
Units in Package 1
Unit Size 0.23 oz
Indications Uses: For temporary relief of pain and itching associated with cold sores and fever blisters. First aid to help prevent infection.
Directions Age group directions: Adults and Children 2 Years of Age and Over: Clean the affected area. Apply a small amount of this product to the cold sore or fever blister 1 to 3 times daily. Do not bandage. Children Under 2 Years of Age: Ask a doctor.
Ingredients Active Ingredients: Camphorated Phenol (Camphor 10.8% and Phenol 4.7%). Purpose: Pain Reliever/Antiseptic. Inactive Ingredients: Colloidal Silicon Dioxide, Eucalyptus Oil, Glycerin, Light Mineral Oil

Reviews From Real Customers

Anon444

19. HERPATCH Cold Sore Serum 5ml

HERPATCH Cold Sore Serum 5ml

  • Herpatch Cold Sore Serum has instant effect
  • Treats every stage of the cold sore
  • The White Serum will form a patch over the wound
  • The Physical Shield helps to make the cold sore largely
  • Protects the skin from drying out

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eCrater – blueberryland
Oneway Beauty

Product Details

Specifications

Details
Product Dimensions 0.79 x 3.35 x 5.91 inches

Reviews From Real Customers

purplejude7
9568annette
loveinklady

20. Galpharm Cold Sore Cream 2g

Galpharm Cold Sore Cream 2g

  • At tingling…
  • Or at blistering.
  • Speeds recovery.

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Pharma Oasis

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uk2015.sofi
atkinso84

Conclusion

There are many ways to treat cold sores, but cream is one of the most effective. It can speed up the healing process and help to prevent future outbreaks. There are a variety of creams available, so it is important to find one that works best for you.

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